Phleomycin resistance as a dominant selectable marker in CHO cells

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

A complementation analysis of the restriction and modification of DNA in Escherichia coli

1969 • 3,866 citations

DNA cloning : a practical approach

1985 • 2,302 citations

Isolation of High‐Molecular‐Weight DNA from Mammalian Cells

1973 • 1,723 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

A new dominant hybrid selective marker for higher eukaryotic cells

1981 • 662 citations

Biochemistry and genetics of cellulose degradation.

1988 • 383 citations

The Prokaryotic Transposable Element Tn5

1983 • 244 citations

Tissue-specific expression is conferred by a sequence from the 5′ end of the rat albumin gene.

1984 • 202 citations

Completion of the nucleotide sequence of the central region of Tn5confirms the presence of three resistance genes

1985 • 199 citations

Dimethyl sulfoxide enhances polyethylene glycol-mediated somatic cell fusion

1976 • 199 citations

Expression in mammalian cells of a gene fromStreptomyces albonigerconferring puromycin resistance

1986 • 183 citations

Transformation of mouse fibroblasts to methotrexate resistance by a recombinant plasmid expressing a prokaryotic dihydrofolate reductase.

1981 • 164 citations

Transformation of mammalian cells with an amplifiable dominant-acting gene.

1980 • 158 citations

High-frequency transfection of CHO cells using polybrene

1986 • 154 citations

Lack of metabolism as the biochemical basis of bleomycin-induced pulmonary toxicity.

1983 • 133 citations

Factors governing the expression of a bacterial gene in mammalian cells.

1981 • 126 citations

Nonreciprocal exchanges of information between DNA duplexes coinjected into mammalian cell nuclei.

1985 • 120 citations

Specificity of deoxyribonucleic acid cleavage by bleomycin, phleomycin, and tallysomycin

1982 • 118 citations

The cloning and reintroduction into animal cells of a functional CAD gene, a dominant amplifiable genetic marker

1981 • 104 citations

LEU2 directed expression of ?-galactosidase activity and phleomycin resistance in Yarrowia lipolytica

1987 • 91 citations

Bleomycin resistance: a new dominant selectable marker for plant cell transformation

1986 • 91 citations

Construction of a fusion gene that confers resistance against hygromycin B to mammalian cells in culture

1985 • 86 citations

Phleomycin resistance encoded by the ble gene from transposon Tn 5 as a dominant selectable marker in Saccharomyces cerevisiae

1987 • 82 citations

Expression of prokaryotic genes for hygromycin B and G418 resistance as dominant-selection markers in mouse L cells

1984 • 77 citations

Plasmid-determined bleomycin resistance in Staphylococcus aureus

1987 • 71 citations

Structure and action of bleomycin.

1976 • 65 citations

Long-term multiplication of the Chinese hamster ovary (CHO) cell line in a serum-free medium

1985 • 43 citations

Selection and preliminary characterization of cycloleucine-resistant CHO cells affected in methionine metabolism

1978 • 16 citations

Site specificity of bleomycin cleavage in purified and intracellular simian virus 40 DNA

1987 • 15 citations