Modulation of transcription of rRNA genes by rapamycin

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

1991 • 1,937 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics.

1987 • 1,216 citations

FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro.

1987 • 1,209 citations

Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization.

1975 • 908 citations

Cyclosporin A, FK-506, and Rapamycin: Pharmacologic Probes of Lymphocyte Signal Transduction

1992 • 675 citations

Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin.

1990 • 613 citations

Inhibition of the immune response by rapamycin, a new antifungal antibiotic

1977 • 444 citations

Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: One in the presence and one in the absence of CsA

1991 • 399 citations

Activity of rapamycin (AY-22,989) against transplanted tumors.

1984 • 337 citations

TRANSCRIPTION OF CLONED EUKARYOTIC RIBOSOMAL RNA GENES

1986 • 333 citations

Immunosuppressants implicate protein phosphatase regulation of K+ channels in guard cells.

1993 • 250 citations

Cyclosporin A inhibits an initial step in folding of transferrin within the endoplasmic reticulum

1991 • 168 citations

Rapamycin (AY-22,989), a new antifungal antibiotic. III. In vitro and in vivo evaluation.

1978 • 159 citations

Eukaryotic Nuclear RNA Polymerases

1976 • 134 citations

Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription.

1991 • 123 citations

Control points in eucaryotic ribosome biogenesis

1991 • 87 citations

FK-506 and cyclosporin A : immunosuppressive mechanism of action and beyond

1992 • 81 citations

Hormonal regulation of transcription of rDNA. Purification and characterization of the hormone-regulated transcription factor IC.

1990 • 63 citations

Pharmacology of cyclosporine (sandimmune). I. Introduction.

1990 • 62 citations

Glucocorticoid inhibition of initiation of transcription of the DNA encoding rRNA (rDNA) in lymphosarcoma P1798 cells.

1984 • 59 citations

Hormonal regulation of transcription of rDNA. Formation of initiated complexes by RNA polymerase I in vitro.

1990 • 39 citations

Cyclosporin A inhibits rDNA transcription in lymphosarcoma P1798 cells.

1987 • 37 citations

Hormonal regulation of transcription of rDNA. The role of TFIC in formation of initiation complexes.

1990 • 36 citations

Structure and organization of mouse U3B RNA functional genes.

1988 • 34 citations

Cyclosporin A: new insights for cell biologists and biochemists.

1990 • 26 citations

Properties of a cell-culture line derived from lymphosarcoma p1798

1980 • 25 citations

Demethoxyrapamycin (AY-24,668),a new antifungal antibiotic.

1983 • 21 citations

Copurification of RNA polymerase I and the glucocorticoid-regulated transcription factor IC

1992 • 11 citations