.alpha.-Spirocyclopentyl- and .alpha.-spirocyclopropyl-.gamma.-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant .alpha.,.alpha.-disubstituted .gamma.-butyrolactones

Palladium-catalyzed carbonylation of enol triflates. A novel method for one-carbon homologation of ketones to α,β-unsaturated carboxylic acid derivatives

1985 • 180 citations

Stereochemistry of the Formation and Decomposition of 1-Pyrazolines

1962 • 116 citations

Barbiturate recognition site on the GABA/benzodiazepine receptor complex is distinct from the picrotoxinin/TBPS recognition site

1984 • 80 citations

A new simple conversion of α,β-unsaturated carbonyl compounds into their corresponding cyclopropyl ketones and esters

1975 • 73 citations

‘Inverse agonists’, cooperativity and drug action at benzodiazepine receptors

1986 • 52 citations

Anticonvulsant properties of alpha, gamma, and alpha, gamma-substituted gamma-butyrolactones.

1982 • 32 citations

Binding interactions of convulsant and anticonvulsant gamma-butyrolactones and gamma-thiobutyrolactones with the picrotoxin receptor.

1990 • 28 citations

Alpha-Substituted γ-Butyrolactones: New Class of Anticonvulsant Drugs

1982 • 24 citations

Comparison of epileptogenic properties of unsubstituted and beta-alkyl-substituted gamma-butyrolactones.

1982 • 21 citations

Alkyl-substituted γ-butyrolactones act at a distinct site allosterically linked to the TBPS/picrotoxinin site on the GABAA receptor complex

1993 • 21 citations

A new spiro-annelation procedure: intramolecular decarboxylative alkylation of β-keto-esters

1981 • 19 citations

Stereochemical studies in substituted cyclopentanecarboxylates

1969 • 7 citations

Effects of anticonvulsant and convulsant gamma-butyrolactones and thiobutyrolactones on gaba-mediated chloride uptake

1987 • 7 citations

2,5-Dimethylcyclopentanecarboxylic Acids

1950 • 6 citations

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