Radiotherapy and chemotherapy in combined clinical trials: Problems and promise

COMBINED 5-FLUOROURACIL AND SUPERVOLTAGE RADIATION THERAPY OF LOCALLY UNRESECTABLE GASTROINTESTINAL CANCER

1969 • 739 citations

The treatment of Wilms' tumor. Results of the national Wilms' tumor study

1976 • 462 citations

Potentiation of X-Ray Effects by Actinomycin D

1959 • 370 citations

Radiation and High-Dose Metronidazole in Supratentorial Glioblastomas

1976 • 309 citations

Bleomycin, an Antitumor Antibiotic

1972 • 293 citations

Quantification of combined radiation therapy and chemotherapy effects on critical normal tissues

1976 • 253 citations

The role of combined chemotherapy in the treatment of rhabdomyosarcoma in children

1974 • 235 citations

Disease-free survival in children with Ewing's sarcoma treated with radiation therapy and adjuvant four-drug sequential chemotherapy

1974 • 232 citations

Methotrexate: clinical pharmacology, current status and therapeutic guidelines

1977 • 203 citations

Preoperative versus postoperative radiotherapy, single versus multiple courses of actinomycin d, in the treatment of Wilms' tumor. Preliminary results of a controlled clinical trial conducted by the international society of paediatric oncology (S.I.O.P.)

1976 • 197 citations

Favorable response of metastatic osteogenic sarcoma to pulse high-dose methotrexate with citrovorum rescue and radiation therapy

1973 • 187 citations

[Hodgkin's disease].

1973 • 177 citations

TEACHING HOSPITAL FOR SOUTHERN RHODESIA

1964 • 171 citations

The cardiotoxicity of adriamycin and daunomycin in children

1976 • 168 citations

Adriamycin and Enhanced Radiation Reaction in Normal Esophagus and Skin

1976 • 168 citations

Enhanced pulmonary toxicity with bleomycin and radiotherapy in oat cell lung cancer

1976 • 164 citations

Brief Communication: Therapy of Advanced Colorectal Cancer With a Combination of 5-Flourouracil, Methyl-l,3-cis(2-chlorethyl)-1-nitrosourea, and Vincristine2

1975 • 163 citations

Adriamycin Activating a Recall Phenomenon After Radiation Therapy

1974 • 163 citations

LEVAMISOLE IN ADVANCED HUMAN BREAST CANCER

1976 • 162 citations

Large-dose bleomycin therapy and pulmonary toxicity. A possible role of prior radiotherapy.

1976 • 154 citations

THE FAMILY DOCTOR IN THE CONTEXT OF BRITAIN'S SOCIAL SERVICE.

1965 • 142 citations

Large-Dose Bleomycin Therapy and Pulmonary Toxicity

1976 • 123 citations

Lung cancer: Clinical trial of radiotherapy alone vs. Radiotherapy plus cyclophosphamide

1972 • 123 citations

The management of stages I, II, and III Hodgkin's disease with combined radiotherapy and chemotherapy

1975 • 117 citations

Combined modality therapy for intracranial tumors

1975 • 112 citations

Combined modality therapy for intracranial tumors

1975 • 107 citations

SMALL-CELL CARCINOMA OF THE LUNG: ATTEMPT TO REMEDY CAUSES OF PAST THERAPEUTIC FAILURE

1976 • 106 citations

COMPARISON OF TREATMENT POLICIES IN INOPERABLE BRONCHIAL CARCINOMA

1971 • 104 citations

Localized ewing's sarcoma—treatment and results

1974 • 102 citations

Acute and late effects on normal tissues following combined chemo- and radiotherapy for childhood rhabdomyosarcoma and Ewing's sarcoma

1976 • 99 citations

Combination therapy of urogenital embryonal rhabdomyosarcoma in children

1973 • 86 citations

Hydroxyurea and Radiotherapy in Head and Neck Cancer

1971 • 86 citations

Combination chemotherapy and radiation therapy in the treatment of metastatic osteogenic sarcoma

1975 • 76 citations

Combined therapy in advanced head and neck cancer: a randomized study.

1972 • 72 citations

HYDROXYUREA: A RADIOSENSITIZER IN THE TREATMENT OF NEOPLASMS OF THE HEAD AND NECK

1969 • 65 citations

Whole-Lung Irradiation for Metastatic Tumor

1969 • 65 citations

CHILDHOOD RHABDOMYOSARCOMA

1975 • 64 citations

Fatal Pulmonary Reaction From Low Doses of Bleomycin

1976 • 64 citations

Hydroxyurea and radiation therapy in advanced cervical cancer

1974 • 62 citations

Studies on the folic acid vitamins. VII. The effects of large doses of amethopterin in patients with cancer.

1962 • 62 citations

EVALUATION OF THERAPEUTIC RESULTS IN EWING’S SARCOMA

1975 • 61 citations

NEPHRITIS IN TWO CHILDREN AFTER IRRADIATION AND CHEMOTHERAPY FOR NEPHROBLASTOMA

1974 • 57 citations

SEQUENTIAL CHEMOTHERAPY AND RADIATION THERAPY OF BUCCAL MUCOSA CARCINOMA IN SOUTH INDIA

1968 • 57 citations

Fatal pulmonary reaction from low doses of bleomycin. An idiosyncratic tissue response

1976 • 56 citations

The management of abdominal neuroblastoma

1975 • 49 citations

Intra-arterial methotrexate chemotherapy and telecobalt therapy in cancer of the oral cavity and oropharynx

1974 • 47 citations

IRRADIATION OF THE LIVER IN CHILDREN: ACUTE EFFECTS ENHANCED BY CONCOMITANT CHEMOTHERAPEUTIC ADMINISTRATION?

1971 • 47 citations

Radiotherapy plus 5-Fu compared to radiotherapy alone for inoperable and unresectable bronchogenic carcinoma

1972 • 46 citations

Combined therapy in advanced head and neck cancer: hydroxyurea and radiotherapy.

1975 • 45 citations

Urinary-bladder toxicity following pelvic irradiation and simultaneous cyclophosphamide therapy

1976 • 45 citations

Cyclophosphamide treatment of patients with localized and regional neuroblastoma. A randomized study

1976 • 42 citations

Sequential Chemotherapy and Radiotherapy

1966 • 41 citations

Treatment of ovarian cancer with thiotepa.

1968 • 40 citations

The rationale for curative radiotherapy for ovarian carcinoma

1975 • 40 citations

A Clinical Study of Chemical Radiosensitization1

2015 • 40 citations

Split-course irradiation compared to split-course irradiation plus hydroxyurea in inoperable bronchogenic carcinoma—a randomized study of 53 patients

1974 • 38 citations

A clinical pharmacologic study of chemotherapy and x-ray therapy in lung cancer

1967 • 33 citations

Combination chemotherapy with CCNU, vincristine and methotrexate in primary and metastatic brain tumors

1975 • 32 citations

Recall Injury from Adriamycin

1975 • 31 citations

Comparative trial of chemotherapy and radiotherapy in patients with non-resectable cancer of the lung

1963 • 29 citations

COMBINATION THERAPY WITH DRUGS AND RADIATION

1973 • 25 citations

Recent Trials in the Treatment of Maxillary Sinus Carcinoma, With Special Reference to the Chemical Potentiation of Radiation Therapy

1971 • 25 citations

Carcinogenesis by Cancer Chemotherapeutic Agents: Second Malignancies Complicating Hodgkin’s Disease in Remission

1974 • 24 citations

A randomized study of irradiation and vinblastine in lung cancer

1970 • 23 citations

Cyclophosphamide (NSC-26271) as adjuvant to radiotherapy in the treatment of unresectable bronchogenic carcinoma.

1973 • 23 citations

A Randomized Study Comparing Irradiation Alone to Irradiation Plus Procarbazine in Inoperable Bronchogenic Carcinoma

1973 • 22 citations

Advanced ovarian cancer: therapy with radiation and cyclophosphamide in a random series.

1972 • 20 citations

IONIZING RADIATION AND VINCRISTINE: POSSIBLE NEUROTOXIC SYNERGISM.

1970 • 19 citations

Use of Methotrexate and Radiation Therapy for Advanced Cancer of the Head and Neck

2015 • 16 citations

Daunomycin, Adriamycin, and Recall Effect

1976 • 16 citations

Résultats d'un essai thérapeutique clinique sur une association radiothérapie et chimiothérapie dans les cancers broncho-pulmonaires

1968 • 15 citations

"SUPPRESSIVE" CHEMOTHERAPY IN BRONCHOGENIC CARCINOMA: A RANDOMIZED PROSPECTIVE CLINICAL TRIAL.

1965 • 14 citations

Clinical Studies of 5-Fluorouracil as Adjuvant to Radiotherapy1

2015 • 13 citations

The management of Wilms' tumor: A comparison of two regimens

1974 • 13 citations

Increased clinically symptomatic pulmonary radiation reactions with adjuvant chemotherapy.

1974 • 13 citations

Treatment of Metastatic Wilms's Tumor

1974 • 12 citations

Preliminary report on the treatment of nonresectable cancer of the lung.

1974 • 10 citations

Coordinated treatment of childhood rhabdomyosarcoma.

1975 • 9 citations

COMBINED CHEMOTHERAPY AND RADIOTHERAPY IN CARCINOMA OF THE LUNG

1965 • 8 citations

Results of the Gynecologic Oncology Group trials on ovarian cancer: preliminary report.

1975 • 7 citations

Wilm's tumour

1974 • 6 citations

[Radiotherapy of the inoperable bronchial carcinoma in combination with endoxan therapy].

1972 • 5 citations

Chemotherapy in bronchogenic carcinoma.

1977 • 4 citations

Comparative evaluation of combined radiation-chlorambucil treatment of ovarian carcinomatosis

1975 • 4 citations

Integrated therapy for Ewing's sarcoma.

1975 • 3 citations

Results of the Gynecologic Oncology Group trials on ovarian cancer: preliminary report.

1975 • 2 citations

Methotrexate in the treatment of tumours of the oto-rhino-laryngeal region.

1970 • 2 citations