Relative roles of decay‐accelerating factor, membrane cofactor protein, and CD59 in the protection of human endothelial cells against complement‐mediated lysis

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A Laboratory manual

1989 • 6,833 citations

TECHNOLOGICAL EXAMINATION OF LOW‐FIRED TERRACOTTA STATUES FROM AYIA IRINI, KEA

1982 • 1,253 citations

CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.

1989 • 640 citations

Isolation of a human erythrocyte membrane glycoprotein with decay-accelerating activity for C3 convertases of the complement system.

1982 • 603 citations

Affected erythrocytes of patients with paroxysmal nocturnal hemoglobinuria are deficient in the complement regulatory protein, decay accelerating factor.

1983 • 438 citations

Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria.

1989 • 407 citations

Inherited Complete Deficiency of 20-Kilodalton Homologous Restriction Factor (CD59) as a Cause of Paroxysmal Nocturnal Hemoglobinuria

1990 • 360 citations

Cloning of decay-accelerating factor suggests novel use of splicing to generate two proteins

1987 • 359 citations

Release of decay-accelerating factor (DAF) from the cell membrane by phosphatidylinositol-specific phospholipase C (PIPLC). Selective modification of a complement regulatory protein.

1986 • 358 citations

Isolation from Human Erythrocytes of a New Membrane Protein Which Inhibits the Formation of Complement Transmembrane Channels1

1988 • 266 citations

Cloning and characterization of cDNAs encoding the complete sequence of decay-accelerating factor of human complement.

1987 • 256 citations

Homologous species restriction in lysis of human erythrocytes: a membrane-derived protein with C8-binding capacity functions as an inhibitor.

1986 • 241 citations

Isolation of a human erythrocyte membrane protein capable of inhibiting expression of homologous complement transmembrane channels.

1986 • 240 citations

Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins.

1988 • 215 citations

Preparation of F(ab′)2 fragments from mouse IgG of various subclasses

1983 • 208 citations

A novel membrane glycoprotein capable of inhibiting membrane attack by homologous complement

1989 • 203 citations

Deficiency of the homologous restriction factor in paroxysmal nocturnal hemoglobinuria.

1987 • 167 citations

Relationship between the membrane inhibitor of reactive lysis and the erythrocyte phenotypes of paroxysmal nocturnal hemoglobinuria.

1989 • 153 citations

Identification of human erythrocyte blood group antigens on decay- accelerating factor (DAF) and an erythrocyte phenotype negative for daf

1988 • 146 citations

Structural basis for variations in the sensitivity of human decay accelerating factor to phosphatidylinositol-specific phospholipase C cleavage.

1990 • 144 citations

Decay-accelerating factor is present on cultured human umbilical vein endothelial cells.

1986 • 129 citations

Phospholipid-anchored and transmembrane versions of either decay-accelerating factor or membrane cofactor protein show equal efficiency in protection from complement-mediated cell damage.

1991 • 127 citations

Membrane cofactor protein of complement is present on human fibroblast, epithelial, and endothelial cells.

1989 • 126 citations

Complement-mediated tumor cell damage induced by antibodies against membrane cofactor protein (MCP, CD46).

1990 • 105 citations

Tissue distribution of HRF20, a novel factor preventing the membrane attack of homologous complement, and its predominant expression on endothelial cells in vivo.

1990 • 101 citations

Biosynthesis and glycosylation of the human complement regulatory protein decay-accelerating factor.

1986 • 87 citations

Biosynthesis of complement factor H by human umbilical vein endothelial cells. Regulation by T cell growth factor and IFN-gamma.

1989 • 77 citations

A 19-kDa human erythrocyte molecule H19 is involved in rosettes, present on nucleated cells, and required for T cell activation. Comparison of the roles of H19 and LFA-3 molecules in T cell activation.

1989 • 77 citations

A polymorphism of the complement regulatory protein MCP (membrane cofactor protein or gp45-70).

1987 • 74 citations

Regulatory control of the terminal complement proteins at the surface of human endothelial cells: neutralization of a C5b-9 inhibitor by antibody to CD59

1990 • 72 citations

Isolation and characterization of a membrane-attack-complex-inhibiting protein present in human serum and other biological fluids

1990 • 65 citations

CD59 expressed by human endothelial cells functions as a protective molecule against complement‐mediated lysis

1992 • 58 citations

Characterization of three monoclonal antibodies to membrane co-factor protein (MCP) of the complement system and quantification of MCP by radioassay

1991 • 58 citations

The CD59 antigen is a structural homologue of murine Ly‐6 antigens but lacks interferon inducibility

1990 • 54 citations

Expression of HRF20, a regulatory molecule of complement activation, on peripheral blood mononuclear cells.

1990 • 42 citations

Protection of human amniotic epithelial cells (HAEC) from complement-mediated lysis: expression on the cells of three complement inhibitory membrane proteins.

1990 • 23 citations