Calicheamicin-conjugated humanized anti-CD33 monoclonal antibody (gemtuzumab zogamicin, CMA-676) shows cytocidal effect on CD33-positive leukemia cell lines, but is inactive on P-glycoprotein-expressing sublines

Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients

1997 • 1,431 citations

Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies

1985 • 927 citations

Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes.

1987 • 923 citations

P-glycoprotein and multidrug resistance

1996 • 549 citations

Calichemicins, a novel family of antitumor antibiotics. 2. Chemistry and structure of calichemicin .gamma.1I

1987 • 516 citations

Selective Ablation of Acute Myeloid Leukemia Using Antibody-Targeted Chemotherapy: A Phase I Study of an Anti-CD33 Calicheamicin Immunoconjugate

1999 • 458 citations

Selective Ablation of Acute Myeloid Leukemia Using Antibody-Targeted Chemotherapy: A Phase I Study of an Anti-CD33 Calicheamicin Immunoconjugate

1999 • 415 citations

Calichemicins, a novel family of antitumor antibiotics. 1. Chemistry and partial structure of calichemicin .gamma.1I

1987 • 381 citations

Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules

1995 • 303 citations

Modified histogram subtraction technique for analysis of flow cytometry data

1988 • 251 citations

Calicheamicin γ ₁ ^I and DNA: Molecular Recognition Process Responsible for Site-Specificity

1989 • 236 citations

Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones.

1986 • 231 citations

Treatment With a New Synthetic Retinoid, Am80, of Acute Promyelocytic Leukemia Relapsed From Complete Remission Induced by All-trans Retinoic Acid

1997 • 191 citations

Role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia.

1996 • 135 citations

Dose-escalation trial of M195 labeled with iodine 131 for cytoreduction and marrow ablation in relapsed or refractory myeloid leukemias.

1993 • 129 citations

Immunotoxins against cancer

1994 • 123 citations

Specific abstraction of the 5'S- and 4'-deoxyribosyl hydrogen atoms from DNA by calicheamicin .gamma.1I

1992 • 108 citations

Radiolabeled anti-CD33 monoclonal antibody M195 for myeloid leukemias.

1995 • 94 citations

The prognostic significance of the expression and function of multidrug resistance transporter proteins in acute myeloid leukemia: studies of the Southwest Oncology Group Leukemia Research Program.

1997 • 85 citations

Monoclonal antibody-based therapies for hematologic malignancies.

1998 • 82 citations

P-glycoprotein in Adult Hematologic Malignancies

1995 • 67 citations

Anti-MY9-blocked-ricin: an immunotoxin for selective targeting of acute myeloid leukemia cells

1991 • 59 citations

Quantitative analysis of exocytosis directly visualized in living chromaffin cells

1991 • 58 citations

Isolation of small, primitive human hematopoietic stem cells: distribution of cell surface cytokine receptors and growth in SCID-Hu mice

1995 • 57 citations

FDP D-dimer induces the secretion of interleukin-1, urokinase-type plasminogen activator, and plasminogen activator inhibitor-2 in a human promonocytic leukemia cell line

1991 • 57 citations

Calicheamicin θ: A Rationally Designed Molecule with Extremely Potent and Selective DNA Cleaving Properties and Apoptosis Inducing Activity

1994 • 55 citations

Antibody-Directed Enzyme Prodrug Therapy

1994 • 54 citations

Optimal immunocytochemical and flow cytometric detection of P-gp, MRP and LRP in childhood acute lymphoblastic leukemia

1997 • 45 citations

Humanized M195 monoclonal antibody conjugated to recombinant gelonin: an anti-CD33 immunotoxin with antileukemic activity.

1998 • 43 citations

Comparison of cyclosporin A and SDZ PSC833 as multidrug-resistance modulators in a daunorubicin-resistant Ehrlich ascites tumor

1992 • 42 citations

Approaches to improved antibody- and peptide-mediated targeting for imaging and therapy of cancer

1994 • 26 citations

Relationship between multidrug resistant gene expression and multidrug resistant-reversing effect of MS-209 in various tumor cells

1995 • 23 citations

Modulation of nicotinamide adenine dinucleotide and poly(adenosine diphosphoribose) metabolism by calicheamicin γ1 in human HL-60 cells

1990 • 22 citations

Improved flow‐cytometric detection of low P‐glycoprotein expression in leukaemic blasts by histogram subtraction analysis

1994 • 21 citations

New Flow Cytometric Method for Detection of Minimally Expressed Multidrug Resistance P‐Glycoprotein on Normal and Acute Leukemia Cells Using Biotinylated MRK16 and Streptavidin‐RED670 Conjugate

1995 • 20 citations

Antibody-directed enzyme prodrug therapy (Adept)

1994 • 17 citations

Expression of multidrug resistance P‐glycoprotein in myeloid progenitor cells of different phenotype: comparison between normal bone marrow cells and leukaemia cells

1996 • 17 citations

Randomized study of indivicualized induction therapy with or without etoposide in adult acute myeloid leukemia (except for M3)(JALSG-AML92 study)and analysis of prognostic factors

1997 • 7 citations

Deleted Work

1955 • 0 citations