pH in human tumour xenografts: effect of intravenous administration of glucose

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

1989 • 3,308 citations

Acid pH in tumors and its potential for therapeutic exploitation.

1989 • 1,633 citations

Sequence and Structure of a Human Glucose Transporter

1985 • 1,557 citations

The relevance of tumour pH to the treatment of malignant disease

1984 • 886 citations

Elevated Levels of Glucose Transport and Transporter Messenger RNA Are Induced by ras or src Oncogenes

1987 • 789 citations

Enzymology of Cancer Cells

1977 • 641 citations

Are cancer cells acidic?

1991 • 576 citations

Over-expression of facilitative glucose transporter genes in human cancer

1990 • 468 citations

Enzymology of Cancer Cells

1977 • 420 citations

p H-Sensitive Liposomes: Possible Clinical Implications

1980 • 410 citations

Facilitative glucose transporters: an expanding family

1990 • 316 citations

Transformation of Rat Fibroblasts by FSV Rapidly Increases Glucose Transporter Gene Transcription

1987 • 286 citations

The glycolysis and respiration of tumors

1961 • 285 citations

Blood flow, metabolism, cellular microenvironment, and growth rate of human tumor xenografts.

1989 • 266 citations

über den Stoffwechsel der Carcinomzelle

1925 • 239 citations

The Utilization of Carbohydrates by Human Cell Cultures

1958 • 206 citations

Blood flow, oxygen consumption, and tissue oxygenation of human breast cancer xenografts in nude rats.

1987 • 183 citations

pH STUDIES IN HUMAN MALIGNANT TUMOURS

1966 • 157 citations

Glucose metabolism in drug-sensitive and drug-resistant human breast cancer cells monitored by magnetic resonance spectroscopy.

1988 • 128 citations

Tumor-selective modification of cellular microenvironment in vivo: effect of glucose infusion on the pH in normal and malignant rat tissues.

1982 • 120 citations

SV40 large tumor antigen can regulate some cellular transcripts in a positive fashion

1982 • 102 citations

Invited review: Response of tumours to hyperglycaemia: characterization, significance and role in hyperthermia

1988 • 67 citations

pH distributions in transplanted neural tumors and normal tissues of BDIX rats as measured with pH microelectrodes.

1982 • 66 citations

Modification of human tumor pH by elevation of blood glucose

1987 • 63 citations

Investigations on the pH of Malignant Tumours in Mice and Humans after the Administration of Glucose

1953 • 62 citations

Hydrogen ion-mediated enhancement of cytotoxicity of bis-chloroethylating drugs in rat mammary carcinoma cells in vitro.

1989 • 54 citations

The effect of glucose pretreatment on the carcinostatic and toxic activities of some alkylating agents

1964 • 44 citations

31P nuclear magnetic resonance study of a human colon adenocarcinoma cultured cell line.

1986 • 43 citations

Proton-mediated liberation of aldophosphamide from a nontoxic prodrug: a strategy for tumor-selective activation of cytocidal drugs.

1989 • 42 citations

The final common pathway of cancer.

1990 • 41 citations

The Vasculature of Xenotransplanted Human Melanomas and Sarcomas on Nude Mice

1989 • 40 citations

pH in human tumor xenografts and transplanted rat tumors: effect of insulin, inorganic phosphate, and m-iodobenzylguanidine.

1992 • 35 citations

Comparison between tumor pH and cell sensitivity to heat in RIF-1 tumors.

1989 • 34 citations

Acute changes of systemic parameters in tumour-bearing rats, and of tumour glucose, lactate, and ATP levels upon local hyperthermia and/or hyperglycaemia

1991 • 33 citations

The Vasculature of Xenotransplanted Human Melanomas and Sarcomas on Nude Mice

1989 • 30 citations

Monoclonal antibody L6-daunomycin conjugates constructed to release free drug at the lower pH of tumor tissue

1991 • 29 citations

Modulation of murine radiation-induced fibrosarcoma-1 tumor metabolism and blood flow in situ via glucose and mannitol administration monitored by 31P and 2H nuclear magnetic resonance spectroscopy.

1991 • 23 citations

Effect of intraperitoneal versus intravenous glucose administration on laser Doppler flow in murine FSaII tumors and normal skin.

1989 • 17 citations

Induction of transient hyperglycaemia in cancer patients

1990 • 13 citations

[Glucose and K+ balance during high-dosage intravenous glucose infusion].

1977 • 9 citations

Fruktose und Sorbit als energieliefernde Substrate für die parenterale Ernährung

1987 • 6 citations

Effect of glucose-mediated pH reduction and cyclophosphamide on oxygenation of transplanted rat tumors

1993 • 6 citations

Über manipulierte Übersäuerung autochthoner Tumoren

1978 • 4 citations

[Fructose and sorbitol as energy-supplying substrates for parenteral nutrition].

1987 • 3 citations