Expression of beta1 integrins in glomerular tissue of Streptozotocin-induced diabetic rats.

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

Focal Adhesions: Transmembrane Junctions Between the Extracellular Matrix and the Cytoskeleton

1988 • 2,137 citations

Signal transduction from the extracellular matrix.

1993 • 1,727 citations

Autophosphorylation of the Focal Adhesion Kinase, ppl25^FAK, Directs SH2-Dependent Binding of pp60^src

1994 • 1,168 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.

1990 • 851 citations

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

1994 • 844 citations

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin.

1992 • 811 citations

Studies on the Renal Glomerular Basement Membrane

1967 • 506 citations

Signaling through focal adhesion kinase

1997 • 468 citations

Fibronectin-Stimulated Signaling from a Focal Adhesion Kinase–c-Src Complex: Involvement of the Grb2, p130^cas, and Nck Adaptor Proteins

1997 • 432 citations

Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin.

1995 • 382 citations

Focal Adhesion Kinase Overexpression Enhances Ras-dependent Integrin Signaling to ERK2/Mitogen-activated Protein Kinase through Interactions with and Activation of c-Src

1997 • 380 citations

Activation of protein kinase C precedes alpha 5 beta 1 integrin-mediated cell spreading on fibronectin.

1993 • 358 citations

Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown.

1993 • 335 citations

Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells.

1994 • 320 citations

Platelet-derived growth factor modulation of focal adhesion kinase (p125FAK) and paxillin tyrosine phosphorylation in Swiss 3T3 cells. Bell-shaped dose response and cross-talk with bombesin.

1994 • 305 citations

Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium.

1993 • 242 citations

Signal transduction by cell adhesion receptors

1995 • 239 citations

Immunohistochemical localization of extracellular matrix components in human diabetic glomerular lesions.

1991 • 196 citations

Colloidal Gold Post-Embedding Immunocytochemistry

1995 • 161 citations

Integrin-dependent signal transduction

1996 • 148 citations

Stimulation of tyrosine phosphorylation and accumulation of GTP-bound p21ras upon antibody-mediated alpha 2 beta 1 integrin activation in T-lymphoblastic cells.

1993 • 127 citations

Mechanisms of Glucose-Enhanced Extracellular Matrix Accumulation in Rat Glomerular Mesangial Cells

1994 • 127 citations

Stimulation of phosphatidylinositol 3'-kinase association with foca adhesion kinase by platelet-derived growth factor.

1994 • 126 citations

Effect of High Glucose on Type IV Collagen Production by Cultured Glomerular Epithelial, Endothelial, and Mesangial Cells

1993 • 120 citations

Integrin overexpression induced by high glucose and by human diabetes: potential pathway to cell dysfunction in diabetic microangiopathy.

1993 • 107 citations

High Glucose Concentration Causes a Decrease in Mesangium Degradation: A Factor in the Pathogenesis of Diabetic Nephropathy

1994 • 92 citations

Signal Transduction from the Extracellular Matrix. A Role for the Focal Adhesion Protein-tyrosine Kinase FAK.

1996 • 89 citations

Alterations in the expression of the a 3 b 1 integrin in certain membrane domains of the glomerular epithelial cells (podocytes) in diabetes mellitus

1997 • 85 citations

Glomerular matrix: Synthesis, turnover and role in mesangial expansion

1994 • 82 citations

Decreased Degradative Enzymes in Mesangial Cells Cultured in High Glucose Media

1995 • 74 citations

Expression of genes related to the extracellular matrix in human endothelial cells. Differential modulation by elevated glucose concentrations, phorbol esters, and cAMP

1991 • 74 citations

STZ-Induced Diabetes Results in Decreased Activity of Glomerular Cathepsin and Metalloprotease in Rats

1993 • 69 citations

Adhesion of rat glomerular epithelial cells to extracellular matrices: Role of β1 integrins

1992 • 59 citations

Renal proteinases and kidney hypertrophy in experimental diabetes

1994 • 49 citations

Stimulation of tyrosine phosphorylation of distinct proteins in response to antibody-mediated ligation and clustering of α3 and α6 integrins

1995 • 46 citations

Alteration in the distribution of type IV collagen in glomerular basal laminae in diabetic rats as revealed by immunocytochemistry and morphometrical approach

1985 • 45 citations

Influence of Acidic Residues and the Kink in the Active-site Helix on the Properties of the Disulfide Oxidoreductase DsbA

1997 • 41 citations

Stimulation of tyrosine‐ and serine‐phosphorylation of focal adhesion kinase in mouse 3T3 cells by fibronectin and fibroblast growth factor

1994 • 40 citations

Structural and Functional Changes in Diabetic Glomerulopathy

1996 • 24 citations

Glucose-Induced Alteration of Integrin Expression and Function in Cultured Human Mesangial Cells

1995 • 23 citations

Ultrastructural distribution of glomerular basement membrane components in experimental diabetes.

1990 • 18 citations