The Dose-Response Relationship of Tranexamic Acid

Applied logistic regression

1990 • 37,000 citations

If nothing goes wrong, is everything all right? Interpreting zero numerators

1983 • 1,101 citations

EFFECT OF APROTININ ON NEED FOR BLOOD TRANSFUSION AFTER REPEAT OPEN-HEART SURGERY

1987 • 696 citations

Reduction in blood loss and blood use after cardiopulmonary bypass with high dose aprotinin (Trasylol)

1989 • 544 citations

Treatment with Desmopressin Acetate to Reduce Blood Loss after Cardiac Surgery

1986 • 517 citations

Clinical Application of Inhibitors of Fibrinolysis

1985 • 460 citations

Aprotinin protects platelets against the initial effect of cardiopulmonary bypass

1990 • 380 citations

Coronary artery surgery in women compared with men: Analyses of risks and long-term results

1983 • 362 citations

Fibrin and Fibrinogen-Related Antigens in Patients with Stable and Unstable Coronary Artery Disease

1987 • 268 citations

Prophylactic tranexamic acid decreases bleeding after cardiac operations

1990 • 258 citations

Effects of high-dose aprotinin on blood loss, platelet function, fibrinolysis, complement, and renal function after cardiopulmonary bypass

1991 • 251 citations

Influence of High-dose Aprotinin Treatment on Blood Loss and Coagulation Patterns in Patients Undergoing Myocardial Revascularization

1990 • 236 citations

Hemostasis Defects Associated with Cardiac Surgery, Prosthetic Devices, and Other Extracorporeal Circuits

1985 • 221 citations

Hemostatic effects of tranexamic acid and desmopressin during cardiac surgery.

1991 • 184 citations

A Trial of Desmopressin (1-Desamino-8-D-Arginine Vasopressin) to Reduce Blood Loss in Uncomplicated Cardiac Surgery

1989 • 177 citations

The hemostatic mechanism after open-heart surgery. I. Studies on plasma coagulation factors and fibrinolysis in 512 patients after extracorporeal circulation.

1975 • 165 citations

Enhanced fibrinolytic activity during cardiopulmonary bypass in open-heart surgery in man is caused by extrinsic (tissue-type) plasminogen activator

1984 • 156 citations

Prophylactic Treatment of Postperfusion Bleeding Using EACA

1989 • 155 citations

The role of epsilon-aminocaproic acid in reducing bleeding after cardiac operation: A double-blind randomized study

1988 • 152 citations

Effect of tranexamic acid on platelet ADP during extracorporeal circulation

1991 • 150 citations

Predictors of excessive blood use after coronary artery bypass grafting

1989 • 114 citations

High-Dose Aprotinin: Hemostatic Effects in Open Heart Operations

1989 • 89 citations

Platelet protection by low-dose aprotinin in cardiopulmonary bypass: Electron microscopic study

1993 • 85 citations

Variability of the Activated Coagulation Time

1988 • 75 citations

Heparin rebound. Studies in patients and volunteers.

1974 • 69 citations

Plasminogen interactions with platelets in plasma

1988 • 68 citations

Does desmopressin acetate prophylaxis reduce blood loss after valvular heart operations? A randomized, double-blind study.

1992 • 50 citations

Low-dose aprotinin in internal mammary artery bypass operations contributes to important blood saving

1992 • 49 citations

NATURAL PROTEINASE INHIBITORS IN EXTRACORPOREAL CIRCULATION

1968 • 45 citations

Thrombosis-related markes in unstable angina pectoris

1991 • 38 citations

Low dose Aprotinin as blood saver in open heart surgery

1991 • 24 citations

LOW DOSE APROTININ OR TRANEXANIC ACID TREATMENT IN CARDIAC SURGERY

1991 • 10 citations

Antifibrinolytic Drugs: Chemistry, Pharmacology, and Clinical Usage

1985 • 9 citations

APROTININ TREATMENT IN CARDIAC SURGERY

1992 • 7 citations

BLOOD SAVING EFFECTS AFTER CARDIAC SURGERY

1992 • 4 citations

APROTININ INHIBITS COAGULATION DURING CARDIOPULMONARY BYPASS IN MAN

1992 • 4 citations

APROTININ DECREASES PERIOPERATIVE BLEEDING AND BLOOD PRODUCT REQUIREMENT DURING THORACIC AORTIC SURGERY PERFORMED WITH EXTRACORPOREAL CIRCULATION

1992 • 4 citations

IS THERE A DIFFERENCE BETWEEN FULL DOSE AND HALF DOSE APROTININ IN CHEST TUBE DRAINAGE FOLLOWING CARDIAC SURGERY?

1992 • 3 citations

PREVENTION OF POST-BYPASS BLEEDING WITH CYKLOKAPRON AND AMICAR

1991 • 3 citations

PREVENTION OF EXCESSIVE BLEEDING INDUCED BY FIBRINOLYSIS AFTER CARDIOPULMONARY BYPASS WITH TRANEXAMIC ACID

1992 • 3 citations

THE EFFECT OF PERIOPERATIVE ADMINISTRATION OF APROTININ IN PRIMARY CARDIAC VALVE REPLACEMENT PATIENTS

1992 • 2 citations