Hypothalamic obesity caused by cranial insult in children: Altered glucose and insulin dynamics and reversal by a somatostatin agonist

Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis.

1979 • 1,145 citations

Octreotide

1996 • 956 citations

Obesity

1997 • 575 citations

Health, United States, 1995

1996 • 403 citations

Acute Hyperinsulinemia and Its Reversal by Vagotomy after Lesions of the Ventromedial Hypothalamus in Anesthetized Rats*

1979 • 266 citations

Hyperphagia, Rage, and Dementia Accompanying a Ventromedial Hypothalamic Neoplasm

1969 • 241 citations

MANIFESTATIONS OF HYPOTHALAMIC OBESITY IN MAN: A COMPREHENSIVE INVESTIGATION OF EIGHT PATIENTS AND A EEVIEW OF THE LITERATURE

1975 • 229 citations

The Effects of Subdiaphragmatic Vagotomy in Rats With Ventromedial Hypothalamic Obesity

1977 • 187 citations

High incidence of obesity in young adults after treatment of acute lymphoblastic leukemia in childhood

1995 • 184 citations

Somatostatin inhibits insulin secretion by a G-protein-mediated decrease in Ca2+ entry through voltage-dependent Ca2+ channels in the beta cell.

1991 • 137 citations

Somatostatin decreases food intake of rats and baboons.

1981 • 123 citations

Beneficial Effect of Diazoxide in Obese Hyperinsulinemic Adults1

1998 • 107 citations

Sibutramine: A Novel New Agent for Obesity Treatment

1995 • 106 citations

Neural pathways involved in the hypothalamic integration of autonomic responses

1981 • 102 citations

Children with Craniopharyngioma

1988 • 99 citations

FAT CELLS

1996 • 90 citations

An hypothesis on the aetiology of obesity: dysfunction of the central nervous system as a primary cause

1985 • 89 citations

Increases in Plasma Insulin Levels in Response to Electrical Stimulation of the Dorsal Motor Nucleus of the Vagus Nerve*

1983 • 89 citations

Long-term follow-up of children with craniopharyngioma

1984 • 86 citations

Peripherally administered somatostatin reduces feeding by a vagal mediated mechanism

1982 • 78 citations

Craniopharyngioma: Endocrine Sequelae of Treatment

1994 • 78 citations

Age-adjusted Analysis of Insulin Responses During Normal and Abnormal Glucose Tolerance Tests in Children and Adolescents

1975 • 74 citations

Involvement of the Cholinergic System in Insulin and Glucagon Oversecretion of Genetic Preobesity*

1985 • 64 citations

Effect of Vagotomy on Serum Insulin in Rats with Paraventricular or Ventromedial Hypothalamic Lesions*

1986 • 58 citations

Beneficial Effect of Diazoxide in Obese Hyperinsulinemic Adults

1998 • 51 citations

Syndromes of hypothalamic obesity in man.

1984 • 50 citations

Evaluation of growth hormone release in children using arginine and l-dopa in combination

1975 • 47 citations

Octreotide: A long-acting inhibitor of endogenous hormone secretion for human metabolic investigations

1994 • 46 citations

Clinical Studies with Dexfenfluramine: From Past to Future

1995 • 43 citations

Transcription factor abnormalities as a cause of beta cell dysfunction in diabetes: a hypothesis

1997 • 38 citations

Somatostatin and the concept of peptide receptor scintigraphy in oncology.

1994 • 34 citations

Age-adjusted analysis of insulin responses during normal and abnormal glucose tolerance tests in children and adolescents

1975 • 30 citations

Characterization of somatostatin binding sites in isolated rat adipocytes

1988 • 26 citations

Insulin Normalization as an Approach to the Pharmacological Treatment of Obesity

1995 • 26 citations

Long-term octreotide treatment reduced hyperinsulinemia, excess body weight and skin lesions in severe obesity with acanthosis nigricans

1996 • 25 citations

Inhibition of Growth Hormone-Stimulated Lipolysis by Somatostatin, Insulin, and Insulin-like Growth Factors (Somatomedins) in Vitro

1988 • 22 citations

Effects of acromegaly treatment and growth hormone on adipose tissue lipoprotein lipase.

1995 • 22 citations

Dose-Dependent Effect of Octreotide on Insulin Secretion after OGTT in Obesity

1997 • 21 citations

Effects of the somatostatin analog, octreotide, on glucose metabolism and insulin sensitivity in insulin-dependent diabetes mellitus

1996 • 21 citations

Weight Relative to Height Before and During Growth Hormone Therapy in Prepubertal Children

1998 • 12 citations

Localization of sequences for the basal and insulin-like growth factor-I inducible activity of the fatty acid synthase promoter in 3T3-L1 fibroblasts

1994 • 11 citations

Effects of acromegaly treatment and growth hormone on adipose tissue lipoprotein lipase

1995 • 9 citations

Deleted Work

1955 • 0 citations