Hydroxyl radicals mediate injury to endothelium-dependent relaxation in diabetic rat

Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor

1986 • 1,211 citations

Direct measurement of free radical generation following reperfusion of ischemic myocardium.

1987 • 1,185 citations

Eicosonoid metabolism and beta-adrenergic mechanisms in coronary arterial smooth muscle: potential compartmentation of cAMP

1986 • 795 citations

Identification of free radicals in myocardial ischemia/reperfusion by spin trapping with nitrone DMPO

1987 • 357 citations

Attenuation of endothelium-dependent relaxation in aorta from diabetic rats

1986 • 350 citations

Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury.

1983 • 338 citations

Prevention of granulocyte-mediated oxidant lung injury in rats by a hydroxyl radical scavenger, dimethylthiourea.

1984 • 322 citations

Impairment of endothelium‐dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin‐induced diabetic rats

1989 • 294 citations

Pulmonary endothelial cell killing by human neutrophils. Possible involvement of hydroxyl radical.

1985 • 262 citations

Impairment of endothelium‐dependent relaxation in aortae from spontaneously diabetic rats

1988 • 255 citations

Contraction of diabetic rabbit aorta caused by endothelium-derived PGH2-TxA2

1989 • 245 citations

Myocardial ischemia and reperfusion: direct evidence for free radical generation by electron spin resonance spectroscopy.

1988 • 200 citations

Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta

1988 • 193 citations

The dopamine autoreceptor agonist B-HT 920 stimulates denervated postsynaptic brain dopamine receptors in rodent and primate models of Parkinson's disease: a novel approach to treatment

1986 • 183 citations

Increased Superoxide Production by Mononuclear Cells of Patients With Hypertriglyceridemia and Diabetes

1988 • 166 citations

Endothelium-Dependent Relaxation in Aorta of BB Rat

1987 • 151 citations

Source of iron in neutrophil-mediated killing of endothelial cells.

1987 • 134 citations

Evidence of Polymorphonuclear Neutrophils (PMN) Activation in Patients With Insulin-Dependent Diabetes Mellitus

1987 • 131 citations

A Contrasting effect of the diabetic state upon the contractile responses of aortic preparations from the rat and rabbit

1987 • 115 citations

Influence of the endothelium on contractile responses of arteries from diabetic rats

1988 • 106 citations

Xanthine oxidase-induced injury to endothelium: role of intracellular iron and hydroxyl radical

1989 • 91 citations

Modulation of vascular tonus by the endothelium in experimental diabetes

1987 • 88 citations

Superoxide anion selectively attenuates catecholamine-induced contractile tension in isolated rabbit aorta

1985 • 54 citations

N,N'-dimethylthiourea dioxide formation from N,N'-dimethylthiourea reflects hydrogen peroxide concentrations in simple biological systems.

1988 • 50 citations

Changes in Vascular Reactivity in Experimental Diabetic Rats: Comparison with Hypothyroid Rats

1988 • 40 citations

Selective Impairment of Endothelium-Dependent Relaxation by Oxygen-Derived Free Radicals: Distinction between Receptor versus Nonreceptor Mediators

1989 • 26 citations

Cardiovascular significance of endotheliumderived vasoactive factors

1991 • 20 citations