Interrelations between substrate cycles and de novo synthesis of pyrimidine deoxyribonucleoside triphosphates in 3T6 cells.

Reduction of Ribonucleotides

1979 • 1,170 citations

Hydroxyurea: Inhibitory Effect on DNA Metabolism

1964 • 425 citations

Inhibition of ribonucleoside diphosphate reductase by hydroxyurea.

1968 • 423 citations

Enzymatic Synthesis of Deoxyribonucleotides

1963 • 314 citations

Biochemistry of Diseases of Immunodevelopment

1981 • 242 citations

Deoxythymidine Kinase of Escherichia coli

1964 • 234 citations

A method for the determination of dATP and dTTP in picomole amounts

1970 • 206 citations

Studies on the uptake of nucleic acid precursors into cells in tissue culture

1968 • 146 citations

Genetic effects of deoxyribonucleotide pool imbalances

1982 • 144 citations

An Enzymatic Method for the Determination of dCTP and dGTP in Picomole Amounts

1970 • 140 citations

Deoxycytidine Kinase

1970 • 133 citations

On the Nature of a Sparing Effect by Thymidine on the Utilization of Deoxycytidine^*

1962 • 126 citations

Evidence for a substrate cycle between AMP and adenosine in isolated hepatocytes.

1983 • 125 citations

Evidence for a Complex Regulating the in Vivo Activities of Early Enzymes Induced by Bacteriophage T4

1974 • 113 citations

Regulation of Ribonucleotide Reductase

1981 • 105 citations

The genetic consequences of nucleotide precursor pool imbalance in mammalian cells

1984 • 94 citations

Regulation of thymidylate synthetase in mouse leukemia cells (L1210).

1980 • 94 citations

Human deoxyuridine triphosphate nucleotidohydrolase. Purification and characterization of the deoxyuridine triphosphate nucleotidohydrolase from acute lymphocytic leukemia.

1979 • 86 citations

Substrate cycles: their role in improving sensitivity in metabolic control

1984 • 86 citations

Dynamics of pyrimidine deoxynucleoside triphosphate pools in relationship to DNA synthesis in 3T6 mouse fibroblasts.

1983 • 76 citations

Effects of inhibition of protein synthesis on DNA replication in cultured mammalian cells

1977 • 76 citations

Meso-α,β-diphenylsuccinate and Hydroxyurea as Inhibitors of Deoxycytidylate Synthesis in Extracts of Ehrlich Ascites and L Cells

1966 • 72 citations

Relations between synthesis of deoxyribonucleotides and DNA replication in 3T6 fibroblasts.

1985 • 71 citations

Evidence for the involvement of substrate cycles in the regulation of deoxyribonucleoside triphosphate pools in 3T6 cells.

1985 • 67 citations

Effects of arabinosyl-cytosine on thymidine triphosphate pools and polyoma DNA replication

1979 • 35 citations

Human placental deoxyadenosine and deoxyguanosine phosphorylating activity.

1983 • 26 citations

Genetic studies on the role of the nucleoside transport function in nucleoside efflux, the inosine cycle, and purine biosynthesis.

1983 • 25 citations

Azidocytidine is a specific inhibitor of deoxyribonucleotide synthesis in 3T6 cells.

1985 • 19 citations

Deoxyribonucleotide Phosphatase from Rat Liver and Cultured Mouse Fibroblasts

1971 • 16 citations

Genetic Studies on the Role of the Nucleoside Transport Function in Nucleoside Efflux, the Inosine Cycle, and Purine Biosynthesis

1983 • 6 citations