Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Psychopharmacology: The third generation of progress

1988 • 3,403 citations

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1982 • 2,148 citations

The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain.

1980 • 1,099 citations

Neural and developmental actions of lithium: A unifying hypothesis

1989 • 1,005 citations

Lithium inhibits adrenergic and cholinergic increases in GTP binding in rat cortex

1988 • 474 citations

Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes

1991 • 468 citations

Inositol lipids in cell signalling.

1989 • 212 citations

Effects of Systemically Administered Lithium on Phosphoinositide Metabolism in Rat Brain, Kidney, and Testis

1985 • 186 citations

Lithium-induced teratogenesis in frog embryos prevented by a polyphosphoinositide cycle intermediate or a diacylglycerol analog

1989 • 185 citations

The purification and properties of myo-inositol monophosphatase from bovine brain

1988 • 174 citations

A review of the biochemical and neuropharmacological actions of lithium

1987 • 171 citations

Inositol polyphosphates and neuronal calcium homeostasis

1988 • 133 citations

Independent phosphatidylinositol synthesis in pituitary plasma membrane and endoplasmic reticulum

1987 • 132 citations

Multiple pathways of inositol polyphosphate metabolism in angiotensin-stimulated adrenal glomerulosa cells.

1988 • 122 citations

Lithium-induced reduction in intracellular inositol supply in cholinergically stimulated parotid gland

1986 • 121 citations

Potentiation by lithium of CMP-phosphatidate formation in carbachol-stimulated rat cerebral-cortical slices and its reversal by myo-inositol

1989 • 115 citations

Differences in the metabolism of inositol and phosphoinositides by cultured cells of neuronal and glial origin

1989 • 110 citations

Subacute and Chronic In Vivo Lithium Treatment Inhibits Agonist‐ and Sodium Fluoride‐Stimulated Inositol Phosphate Production in Rat Cortex

1989 • 109 citations

Acute and chronic lithium treatments influence agonist and depolarization-stimulated inositol phospholipid hydrolysis in rat cerebral cortex.

1987 • 108 citations

Cloning and expression of bovine brain inositol monophosphatase.

1990 • 107 citations

CDP-diglyceride:inositol transferase from rat liver. Purification and properties.

1977 • 98 citations

Reduced inositol polyphosphate accumulation and inositol supply induced by lithium in stimulated cerebral cortex slices

1990 • 97 citations

In vivo measurement of lithium in humans by nuclear magnetic resonance spectroscopy

1988 • 86 citations

Lithium Blocks a Phosphoinositide-Mediated Cholinergic Response in Hippocampal Slices

1988 • 81 citations

Lithium and inositol lipid-linked signalling mechanisms

1987 • 80 citations

Lithium Reduqes the Accumulation or Inositol Polyphosphate Second Messengers Following Cholinergic Stimulation of Cerebral Cortex Slices

1989 • 75 citations

Lithium Selectively Inhibits Muscarinic Receptor‐Stimulated Inositol Tetrakisphosphate Accumulation in Mouse Cerebral Cortex Slices

1988 • 73 citations

Autoradiographic Imaging of Phosphoinositide Turnover in the Brain

1990 • 71 citations

Studies on the metabolic role of myo-inositol. Distribution of radioactive myo-inositol in the male rat

1976 • 66 citations

Chronically Administered Lithium Alters Neither myo‐Inositol Monophosphatase Activity nor Phosphoinositide Levels in Rat Brain

1989 • 55 citations

Lithium and the cell : pharmacology and biochemistry

1991 • 50 citations

Desensitization of muscarinic stimulated hippocampal cell firing is related to phosphoinositide hydrolysis and inhibited by lithium.

1990 • 45 citations

Purification and properties of inositol-1,4-bisphosphatase from bovine brain

1988 • 44 citations

Formation of inositol phosphate isomers in GH3 pituitary tumour cells stimulated with thyrotropin-releasing hormone. Acute effects of lithium ions

1987 • 42 citations

Purification of Phosphatidylinositol Synthetase from Rat Brain by CDP‐Diacylglycerol Affinity Chromatography and Properties of the Purified Enzyme

1985 • 41 citations

The effects of acute and chronic lithium treatment on pilocarpine‐stimulated phosphoinositide hydrolysis in mouse brain in vivo

1990 • 41 citations

Effects of lithium on angiotensin‐stimulated phosphatidylinositol turnover and aldosterone production in adrenal glomerulosa cells: a possible causal relationship

1984 • 40 citations

Interactions between lithium, inositol and mono-oleoylglycerol in the regulation of insulin secretion from isolated perifused rat islets

1989 • 40 citations

Inositol accumulation by brain slices in vitro

1976 • 35 citations

Design and synthesis of 6α-substituted 2β,4α-dihydroxy-1β-phosphoryloxycyclohexanes, potent inhibitors of inositol monophosphatase

1991 • 31 citations

Evidence that Phosphoinositide Metabolism in Rat Cerebral Cortex Stimulated by Pilocarpine, Physostigmine, and Pargyline In Vivo Is Not Changed by Chronic Lithium Treatment

1990 • 20 citations

[3H]-myo-inositol uptake in rat cortical slices

1988 • 14 citations

Influence of lithium on the positive inotropic effect of phenylephrine and isoprenaline in guinea-pig heart

1988 • 11 citations

Coupling of Li+ distribution to the plasma membrane potential of rat cortical synaptosomes.

1986 • 9 citations