Morphine-6-glucoronide: A potent stimulator of locomotor activity in mice

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

1988 • 913 citations

Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.

1989 • 373 citations

Morphine-6-glucuronide, a potent mu agonist

1987 • 365 citations

Morphine-3-glucuronide - a potent antagonist of morphine analgesia

1990 • 341 citations

Antinociceptive and ventilatory effects of the morphine metabolites: morphine-6-glucuronide and morphine-3-glucuronide

1991 • 178 citations

Further evidence that morphine-6 beta-glucuronide is a more potent opioid agonist than morphine.

1992 • 153 citations

Morphine derivatives with diminished opiate receptor potency show enhanced central excitatory activity

1979 • 149 citations

Biochemical basis for analgesic activity of morphine-6-glucuronide—I

1973 • 135 citations

Oral morphine in cancer patients: in vivo kinetics and in vitro hepatic glucuronidation.

1985 • 131 citations

Species difference of site-selective glucuronidation of morphine.

1991 • 128 citations

Morphine 6‐glucuronide: a metabolite of morphine with greater emetic potency than morphine in the ferret

1992 • 66 citations

Opioid δ agonists and endogenous enkephalins induce different emotional reactivity than μ agonists after injection in the rat ventral tegmental area

1991 • 62 citations

Plasma Concentrations and Renal Clearance of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Cancer Patients Receiving Morphine

1993 • 50 citations

Morphine-6-glucuronide contributes to rewarding effects of opiates

1991 • 35 citations

Different biotransformation of morphine in isolated liver cells from guinea pig and rat

1993 • 31 citations

Morphine‐6‐Glucuronide: Receptor Binding Profile in Bovine Caudate Nucleus

1991 • 22 citations

Low-Level Hyperbaric Antagonism of Ethanol-Induced Locomotor Depression in C57BL/6J Mice: Dose Response

1993 • 16 citations