Molecular basis of proton block of L-type Ca2+ channels.

Ionic channels of excitable membranes

1985 • 7,199 citations

Ionic Blockage of Sodium Channels in Nerve

1973 • 1,590 citations

Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

1989 • 922 citations

Calcium channel characteristics conferred on the sodium channel by single mutations

1992 • 776 citations

Physiology of the heart

1977 • 769 citations

Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels

1993 • 614 citations

Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1986 • 534 citations

Modulation of pH by neuronal activity

1992 • 533 citations

CALCIUM CHANNELS: Mechanisms of Selectivity, Permeation, and Block

1987 • 528 citations

Distinctive biophysical and pharmacological properties of class A (BI) calcium channel α1 subunits

1993 • 431 citations

Control of Proton Sensitivity of the NMDA Receptor by RNA Splicing and Polyamines

1995 • 395 citations

Molecular Tuning of Ion Binding to Calcium Signaling Proteins

1994 • 370 citations

Calcium channel beta subunit heterogeneity: functional expression of cloned cDNA from heart, aorta and brain.

1992 • 339 citations

Ca2+ channel selectivity at a single locus for high-affinity Ca2+ interactions

1995 • 277 citations

Pharmacological properties and H+ sensitivity of excitatory amino acid receptor channels in rat cerebellar granule neurones.

1991 • 221 citations

Identification of an external divalent cation-binding site in the pore of a cGMP-activated channel

1993 • 220 citations

Direct measurement of proton transfer rates to a group controlling the dihydropyridine-sensitive Ca2+ channel

1987 • 201 citations

Molecular localization of ion selectivity sites within the pore of a human L-type cardiac calcium channel

1993 • 173 citations

Two Identical Noninteracting Sites in an Ion Channel Revealed by Proton Transfer

1994 • 160 citations

Structural determinants of ion selectivity in brain calcium channel

1993 • 147 citations

Acidosis-related brain damage.

1993 • 143 citations

Identification and molecular localization of a pH-sensing domain for the inward rectifier potassium channel HIR

1995 • 127 citations

Calcium channel current of vascular smooth muscle cells: extracellular protons modulate gating and single channel conductance.

1994 • 111 citations

Depth Asymmetries of the Pore-Lining Segments of the Na+ Channel Revealed by Cysteine Mutagenesis

1996 • 107 citations

Interactions of protons with single open L-type calcium channels. Location of protonation site and dependence of proton-induced current fluctuations on concentration and species of permeant ion.

1989 • 106 citations

Hydrogen ion modulation of Ca channel current in cardiac ventricular cells. Evidence for multiple mechanisms.

1988 • 98 citations

Characterization of the high‐affinity Ca2+ binding sites in the L‐type Ca2+ channel pore in rat phaeochromocytoma cells.

1993 • 94 citations

Interactions of protons with single open L-type calcium channels. pH dependence of proton-induced current fluctuations with Cs+, K+, and Na+ as permeant ions.

1989 • 92 citations

Conformational changes associated with ion permeation in L-type calcium channels

1988 • 81 citations

Glutamate substitution in repeat IV alters divalent and monovalent cation permeation in the heart Ca2+ channel

1995 • 74 citations

Ion Permeation through Calcium Channels

1991 • 64 citations

The influence of pH on glutamate- and depolarization-induced increases of intracellular calcium concentration in cortical neurons in primary culture

1994 • 55 citations

Effects of external protons on single cardiac sodium channels from guinea pig ventricular myocytes.

1991 • 52 citations

Proton block of rat brain sodium channels. Evidence for two proton binding sites and multiple occupancy.

1993 • 41 citations

Evidence for existence of two acid groups controlling the conductance of sodium channel

1981 • 21 citations