Effect of Transforming Growth Factor-β1 on the Cell Growth and Epstein–Barr Virus Reactivation in EBV-Infected Epithelial Cell Lines

TGF-β SIGNAL TRANSDUCTION

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Epstein-Barr Virus

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Direct binding of Smad3 and Smad4 to critical TGFbeta -inducible elements in the promoter of human plasminogen activator inhibitor-type 1gene

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Transforming growth factor-beta: recent progress and new challenges.

1992 • 781 citations

Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer

1998 • 562 citations

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1994 • 447 citations

Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta.

1994 • 431 citations

Physicochemical Activation of Recombinant Latent Transforming Growth Factor-beta's 1, 2, and 3

1990 • 343 citations

Demonstration That Mutation of the Type II Transforming Growth Factor β Receptor Inactivates Its Tumor Suppressor Activity in Replication Error-positive Colon Carcinoma Cells

1995 • 340 citations

Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells

1994 • 325 citations

Cell-to-Cell Contact as an Efficient Mode of Epstein-Barr Virus Infection of Diverse Human Epithelial Cells

1998 • 314 citations

Polymorphic proteins encoded within BZLF1 of defective and standard Epstein-Barr viruses disrupt latency

1987 • 245 citations

Epstein-Barr virus-associated gastric carcinoma and Epstein-Barr virus infection of the stomach.

1994 • 235 citations

Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia.

1990 • 229 citations

Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells.

1996 • 195 citations

Transcriptional analysis of Epstein-Barr virus gene expression in EBV-positive gastric carcinoma: unique viral latency in the tumour cells

1996 • 192 citations

Transforming growth factor beta 1 induces apoptotic cell death in cultured human gastric carcinoma cells.

1992 • 152 citations

Human cytomegalovirus infection induces transcription and secretion of transforming growth factor beta 1

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Establishment and characterization of human signet ring cell gastric carcinoma cell lines with amplification of the c-myc oncogene.

1991 • 141 citations

The Epstein-Barr virus (EBV) BZLF1 immediate-early gene product differentially affects latent versus productive EBV promoters

1989 • 141 citations

Elevated antibody titers to Epstein‐Barr virus prior to the diagnosis of Epstein‐Barr‐virus‐associated gastric adenocarcinoma

1995 • 122 citations

Latent membrane protein-1 induces cyclin D2 expression, pRb hyperphosphorylation, and loss of TGF-beta 1-mediated growth inhibition in EBV-positive B cells.

1995 • 113 citations

Immunoelectron microscopic localization of transforming growth factor beta 1 and latent transforming growth factor beta 1 binding protein in human gastrointestinal carcinomas: qualitative difference between cancer cells and stromal cells.

1993 • 105 citations

Epstein-Barr Virus Promotes Epithelial Cell Growth in the Absence of EBNA2 and LMP1 Expression

1999 • 74 citations

Human malignant thyroid tumors displayed reduced levels of transforming growth factor beta receptor type II messenger RNA and protein.

1997 • 72 citations

Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate.

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Endogenous TGF‐β contributes to the induction of the EBV lytic cycle in two burkitt lymphoma cell lines

1994 • 60 citations

Transforming growth factor‐β1 induces apoptosis in gastric cancer cells through a p53‐independent pathway

1996 • 58 citations

Strain Variation in Epstein-Barr Virus Immediate Early Genes

1993 • 54 citations

Nitric Oxide Down-Regulates Epstein–Barr Virus Reactivation in Epithelial Cell Lines

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Measurement of antigen-specific mouse IgE by a fluorometric reverse (IgE-capture) ELISA

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Reduced Levels of Transforming Growth Factor‐beta Type I Receptor in Human Gastric Carcinomas

1992 • 47 citations

Differential localization of transforming growth factor-β isoforms in human gastric mucosa and overexpression in gastric carcinoma

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Establishment of Epstein‐Barr Virus‐positive Human Gastric Epithelial Cell Lines

1998 • 40 citations

Productive Infection of Epstein–Barr Virus (EBV) in EBV-Genome-Positive Epithelial Cell Lines (GT38 and GT39) Derived from Gastric Tissues

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Differential effect of TPA on cell growth and Epstein-Barr virus reactivation in epithelial cell lines derived from gastric tissues and B cell line Raji.

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Tumorigenesis of Epstein–Barr Virus-Positive Epithelial Cell Lines Derived from Gastric Tissues in the SCID Mouse

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Epstein‐Barr virus induction by a serum factor: IV. Ubiquitous occurrence of the factor within vertebrates and its interaction with defined lymphoid cell lines

1982 • 10 citations