The Rapid Effects of 1,25-Dihydroxyvitamin D3 Require the Vitamin D Receptor and Influence 24-Hydroxylase Activity

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

2000 • 1,411 citations

The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed

1998 • 1,391 citations

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

1995 • 906 citations

Evolution of the nuclear receptor gene superfamily.

1992 • 662 citations

Progesterone Receptor Contains a Proline-Rich Motif that Directly Interacts with SH3 Domains and Activates c-Src Family Tyrosine Kinases

2001 • 582 citations

Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion

1997 • 388 citations

The Vitamin D Receptor and the Syndrome of Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets*

1999 • 363 citations

Activation of MAPK Cascades by G-protein-coupled Receptors: The Case of Gonadotropin-releasing Hormone Receptor

2000 • 343 citations

Deletion of Deoxyribonucleic Acid Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D

2002 • 277 citations

Calcium Transport in Perfused Duodena from Normal Chicks: Enhancement within Fourteen Minutes of Exposure to 1,25-Dihydroxyvitamin D₃*

1984 • 262 citations

Effects of vitamin D3 metabolites on cytosolic free calcium in confluent mouse osteoblasts.

1987 • 246 citations

Vitamin D3 Metabolites Modulate Dihydropyridine-sensitive Calcium Currents in Clonal Rat Osteosarcoma Cells

1989 • 241 citations

Identification of a Membrane Receptor for 1,25-Dihydroxyvitamin D3 Which Mediates Rapid Activation of Protein Kinase C

1998 • 218 citations

Phospholipase C β and Membrane Action of Calcitriol and Estradiol

1997 • 177 citations

Retinoid X Receptor Dominates the Nuclear Import and Export of the Unliganded Vitamin D Receptor

2002 • 149 citations

Isolation and expression of human 1,25-dihydroxyvitamin D3 24-hydroxylase cDNA.

1993 • 144 citations

A Functional Cell Surface Type Receptor Is Required for the Early Action of 1,25-Dihydroxyvitamin D3 on the Phosphoinositide Metabolism in Rat Enterocytes

1989 • 134 citations

Stimulation of Phosphorylation of Mitogen-Activated Protein Kinase by 1α,25-Dihydroxyvitamin D3 in Promyelocytic NB4 Leukemia Cells: A Structure-Function Study*

1998 • 126 citations

Receptors for 1α,25(OH)2D3: Past, Present, and Future

1998 • 123 citations

Transcriptional Synergism between Vitamin D-responsive Elements in the Rat 25-Hydroxyvitamin D3 24-Hydroxylase (CYP24) Promoter

1996 • 122 citations

Subcellular Distribution of Normal and Mutant Vitamin D Receptors in Living Cells

1997 • 118 citations

Vitamin D target proteins: Function and regulation

2003 • 115 citations

Update on biological actions of 1α,25(OH)2-vitamin D3 (rapid effects) and 24R,25(OH)2-vitamin D3

2002 • 113 citations

Protein Kinase C and Mitogen-activated Protein Kinase Are Required for 1,25-Dihydroxyvitamin D3-stimulated Egr Induction

1995 • 104 citations

Role of MAP Kinases in the 1,25-Dihydroxyvitamin D3-induced Transactivation of the Rat Cytochrome P450C24 (CYP24) Promoter

2002 • 103 citations

Tissue resistance to 1,25‐dihydroxyvitamin D without a mutation of the vitamin D receptor gene

1993 • 102 citations

Activation of Raf—Mitogen–Activated Protein Kinase Signaling Pathway by 1,25-Dihydroxyvitamin D3 in Normal Human Keratinocytes

1996 • 95 citations

Rapid Effects of 1,25-Dihydroxyvitamin D₃and Extracellular Ca²⁺on Phospholipid Metabolism in Dispersed Porcine Parathyroid Cells

1990 • 92 citations

Annexin II is the membrane receptor that mediates the rapid actions of 1?,25-dihydroxyvitamin D3

2000 • 90 citations

Structural characterization of the gene encoding rat 25-hydroxyvitamin D3 24-hydroxylase

1993 • 86 citations

Calreticulin inhibits vitamin D₃signal transduction

1995 • 72 citations

Ca2+-channel agonist bay K8644 mimics 1,25(OH)2-vitamin D3 rapid enhancement of Ca2+ transport in chick perfused duodenum

1990 • 70 citations

Two mutations causing vitamin D resistant rickets: modelling on the basis of steroid hormone receptor DNA‐binding domain crystal structures

1994 • 70 citations

Membrane Receptors for Vitamin D Steroid Hormones: Potential NewDrug Targets

2003 • 70 citations

Association of 1 alpha,25-dihydroxyvitamin D3-occupied vitamin D receptors with cellular membrane acceptance sites.

1996 • 64 citations

Rapid 1,25(OH)2-vitamin D3 stimulation of calcium uptake by rat intestinal cells involves a dihydropyridine-sensitive cAMP-dependent pathway

1994 • 61 citations

Molybdate increases intracellular 3‘,5‘-guanosine cyclic monophosphate and stabilizes vitamin D receptor association with tubulin-containing filaments.

1992 • 55 citations

Regulation of messenger ribonucleic acid expression of 1 alpha,25-dihydroxyvitamin D3-24-hydroxylase in rat osteoblasts.

1994 • 53 citations

G?q/11 and G?? proteins and membrane signaling of calcitriol and estradiol

1999 • 53 citations

The 25(OH)D3/1α,25(OH)2D3-24R-hydroxylase: a catabolic or biosynthetic enzyme?

2001 • 51 citations

Tryptophan Missense Mutation in the Ligand‐Binding Domain of the Vitamin D Receptor Causes Severe Resistance to 1,25‐Dihydroxyvitamin D

2002 • 46 citations

1a,25-(OH)2D3 Regulates 25-Hydroxyvitamin D3 24R-Hydroxylase Activity in Growth Zone Costochondral Growth Plate Chondrocytes via Protein Kinase C

2001 • 29 citations

Rapid Actions of 1 -25-Dihydroxyvitamin D3 Physiologic Role

1994 • 19 citations

Influence of the in Vivo Calcium Status on Cellular Calcium Homeostasis and the Level of the Calcium-Binding Protein Calreticulin in Rat Hepatocytes*

2000 • 13 citations