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Relative conformational rigidity in oxytocin and (1-penicillamine)-oxytocin: a proposal for the relationship of conformational flexibility to peptide hormone agonism and antagonism.

Data up to Jan 2025

Published1977
Citations89
References27

Total Citations Per Year

Abstract

References (27)

Temperature dependence of amide proton chemical shifts: The secondary structures of gramicidin S and valinomycin

1969 • 299 citations

Binding of flexible ligands to macromolecules

1975 • 199 citations

Conformation flexibility of the neurohypophyseal hormones oxytocin and lysine-vasopressin. Carbon-13 spin-lattice relaxation study of backbone and side chains

1974 • 77 citations

Conformation of histamine derivatives. 3. Relation between conformation and pharmacological activity

1973 • 68 citations

300-MHz Nuclear Magnetic Resonance Study of Oxytocin in Aqueous Solution: Conformational Implications

1973 • 66 citations

Deuteron magnetic resonance studies on the microdynamical behavior of partially deuterated oxytocin with neurophysin

1973 • 65 citations

An Approach to Conformational Analysis of Peptides and Proteins in Solution Based on a Combination of Nuclear Magnetic Resonance Spectroscopy and Conformational Energy Calculations

1970 • 64 citations

Stimulus-response coupling in neurohypophysial peptide target cells

1975 • 61 citations

Recent advances in renal physiology

1973 • 58 citations

Proposed conformations of oxytocin and selected analogs in dimethyl sulfoxide as deduced from proton magnetic resonance studies

1973 • 53 citations

Conformational Studies of Oxytocin, Lysine Vasopressin, Arginine Vasopressin, and Arginine Vasotocin by Carbon-13 Nuclear Magnetic Resonance Spectroscopy

1973 • 46 citations

Synthesis of specifically deuterated S-benzylcysteines and of oxytocin and related diastereomers deuterated in the half-cystine positions

1976 • 45 citations

Conformational Energy Studies of Oxytocin and Its Cyclic Moiety

1972 • 40 citations

Conformational Studies of Oxytocin and Lysine Vasopressin in Aqueous Solution using High Resolution NMR Spectroscopy

1971 • 40 citations

[1-.beta.-Mercapto-.beta.,.beta.-pentamethylenepropionic acid]oxytocin, a potent inhibitor of oxytocin

1975 • 38 citations

Proton nuclear magnetic resonance double resonance study of oxytocin in aqueous solution

1976 • 37 citations

Model-building of neurohypophyseal hormones

1973 • 33 citations

Conformation of gonadotropin releasing hormone

1976 • 29 citations

Conformational characteristics in solution of the cyclic hexapeptide Gly-Gly-D-Ala-D-Ala-Gly-Gly

1972 • 29 citations

Synthesis of three oxytocin analogs related to [1-deaminopenicillamine]oxytocin prossessing antioxytocic activity

1972 • 25 citations

Conformational heterogeneity in linear peptides in solution: A carbon‐13 NMR study of [Pro3, Pro5] ‐angiotensin‐II

1976 • 16 citations

Conformational flexibility in physiologically active amines

1975 • 14 citations

Synthesis of [1-deamino,4-L-leucine]-oxytocin and [1-deamino,4-L-isoleucine]-oxytocin and some of their pharmacological properties

1970 • 13 citations

On the molecular mechanism of oxytocin action

1970 • 9 citations

Studies on the molecular association of oxytocin and related compounds in dimethyl sulfoxide

1976 • 9 citations

Effects of magnesium ion and oxytocin inhibitors on the uterotonic activity of oxytocin and prostaglandins E2 and F2ALPHA.

1974 • 8 citations

[1-.beta.-Mercapto-.beta.,.beta.-diethylpropionic acid, 4-leucine]-8-lysine-vasopressin and [1-.beta.-mercapto-.beta.,.beta.-diethylpropionic acid, 4-leucine]oxytocin, compounds possessing antihormonal properties

1974 • 5 citations

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Relative conformational rigidity in oxytocin and (1-penicillamine)-oxytocin: a proposal… (1977) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer