Relative conformational rigidity in oxytocin and (1-penicillamine)-oxytocin: a proposal for the relationship of conformational flexibility to peptide hormone agonism and antagonism.
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References (27)
Temperature dependence of amide proton chemical shifts: The secondary structures of gramicidin S and valinomycin
1969 • 299 citations
Binding of flexible ligands to macromolecules
1975 • 199 citations
Conformation flexibility of the neurohypophyseal hormones oxytocin and lysine-vasopressin. Carbon-13 spin-lattice relaxation study of backbone and side chains
1974 • 77 citations
Conformation of histamine derivatives. 3. Relation between conformation and pharmacological activity
1973 • 68 citations
300-MHz Nuclear Magnetic Resonance Study of Oxytocin in Aqueous Solution: Conformational Implications
1973 • 66 citations
Deuteron magnetic resonance studies on the microdynamical behavior of partially deuterated oxytocin with neurophysin
1973 • 65 citations
An Approach to Conformational Analysis of Peptides and Proteins in Solution Based on a Combination of Nuclear Magnetic Resonance Spectroscopy and Conformational Energy Calculations
1970 • 64 citations
Stimulus-response coupling in neurohypophysial peptide target cells
1975 • 61 citations
Recent advances in renal physiology
1973 • 58 citations
Proposed conformations of oxytocin and selected analogs in dimethyl sulfoxide as deduced from proton magnetic resonance studies
1973 • 53 citations
Conformational Studies of Oxytocin, Lysine Vasopressin, Arginine Vasopressin, and Arginine Vasotocin by Carbon-13 Nuclear Magnetic Resonance Spectroscopy
1973 • 46 citations
Synthesis of specifically deuterated S-benzylcysteines and of oxytocin and related diastereomers deuterated in the half-cystine positions
1976 • 45 citations
Conformational Energy Studies of Oxytocin and Its Cyclic Moiety
1972 • 40 citations
Conformational Studies of Oxytocin and Lysine Vasopressin in Aqueous Solution using High Resolution NMR Spectroscopy
1971 • 40 citations
[1-.beta.-Mercapto-.beta.,.beta.-pentamethylenepropionic acid]oxytocin, a potent inhibitor of oxytocin
1975 • 38 citations
Proton nuclear magnetic resonance double resonance study of oxytocin in aqueous solution
1976 • 37 citations
Model-building of neurohypophyseal hormones
1973 • 33 citations
Conformation of gonadotropin releasing hormone
1976 • 29 citations
Conformational characteristics in solution of the cyclic hexapeptide Gly-Gly-D-Ala-D-Ala-Gly-Gly
1972 • 29 citations
Synthesis of three oxytocin analogs related to [1-deaminopenicillamine]oxytocin prossessing antioxytocic activity
1972 • 25 citations
Conformational heterogeneity in linear peptides in solution: A carbon‐13 NMR study of [Pro3, Pro5] ‐angiotensin‐II
1976 • 16 citations
Conformational flexibility in physiologically active amines
1975 • 14 citations
Synthesis of [1-deamino,4-L-leucine]-oxytocin and [1-deamino,4-L-isoleucine]-oxytocin and some of their pharmacological properties
1970 • 13 citations
On the molecular mechanism of oxytocin action
1970 • 9 citations
Studies on the molecular association of oxytocin and related compounds in dimethyl sulfoxide
1976 • 9 citations
Effects of magnesium ion and oxytocin inhibitors on the uterotonic activity of oxytocin and prostaglandins E2 and F2ALPHA.
1974 • 8 citations
[1-.beta.-Mercapto-.beta.,.beta.-diethylpropionic acid, 4-leucine]-8-lysine-vasopressin and [1-.beta.-mercapto-.beta.,.beta.-diethylpropionic acid, 4-leucine]oxytocin, compounds possessing antihormonal properties
1974 • 5 citations