Homeosis and intestinal tumours in Cdx2 mutant mice

Altering the Genome by Homologous Recombination

1989 • 2,021 citations

A Dominant Mutation That Predisposes to Multiple Intestinal Neoplasia in the Mouse

1990 • 1,550 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.

1995 • 582 citations

A molecular gradient in early Drosophila embryos and its role in specifying the body pattern

1986 • 504 citations

Expression of Cdx‐2 in the mouse embryo and placenta: Possible role in patterning of the extra‐embryonic membranes

1995 • 407 citations

Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes

1995 • 350 citations

Differential Staining of Cartilage and Bone in Fetal Mouse Skeleton by Alcian Blue and Alizarin Red S

1976 • 323 citations

[51] Gene targeting in embryonic stem cells

1993 • 320 citations

Structure of the murine homeobox gene cdx-2. Expression in embryonic and adult intestinal epithelium.

1994 • 270 citations

Cancer as a dynamic developmental disorder.

1985 • 216 citations

Homeobox gene expression in the intestinal epithelium of adult mice.

1991 • 212 citations

A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine.

1988 • 202 citations

Murine Cdx-4 bears striking similarities to the Drosophila caudal gene in its homeodomain sequence and early expression pattern

1993 • 169 citations

Homozygosity for theMinallele ofApcresults in disruption of mouse development prior to gastrulation

1995 • 159 citations

Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma.

1995 • 158 citations

Expression and methylation of imprinted genes during in vitro differentiation of mouse parthenogenetic and androgenetic embryonic stem cell lines

1994 • 145 citations

Vertebrate Hox genes and proliferation: an alternative pathway to homeosis?

1995 • 141 citations

Homoeotic transformations in man: Implications for the mechanism of embryonic development and for the organization of epithelia

1985 • 73 citations

[52] Simple screening procedure to detect gene targeting events in embryonic stem cells

1993 • 59 citations

Localization of the Genes Encoding Two Transcription Factors, LMX1 and CDX3, Regulating Insulin Gene Expression to Human Chromosomes 1 and 13

1994 • 57 citations

Mapping of Multiple Intestinal Neoplasia (Min) to Proximal Chromosome 18 of the Mouse

1993 • 53 citations

Chromosomal Localization ofCdx2,a Murine Homologue of theDrosophilaGeneCaudal,to Mouse Chromosome 5

1996 • 21 citations