Pravastatin effectively lowers LDL cholesterol in familial combined hyperlipidemia without changing LDL subclass pattern.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

Quantitative Determination of Serum Triglycerides by the Use of Enzymes

1973 • 3,206 citations

Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol.

1982 • 2,206 citations

Low-Density Lipoprotein Subclass Patterns and Risk of Myocardial Infarction

1988 • 1,722 citations

Hyperlipidemia in Coronary Heart Disease II. GENETIC ANALYSIS OF LIPID LEVELS IN 176 FAMILIES AND DELINEATION OF A NEW INHERITED DISORDER, COMBINED HYPERLIPIDEMIA

1973 • 1,457 citations

Determination of Lecithin: Cholesterol Acyltransfer in Human Blood Plasma

1971 • 559 citations

[24] Nondenaturing polyacrylamide gradient gel electrophoresis

1986 • 520 citations

Myopathy and Rhabdomyolysis Associated With Lovastatin-Gemfibrozil Combination Therapy

1990 • 422 citations

Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia

1983 • 305 citations

Familial Combined Hyperlipidemia Workshop

1989 • 215 citations

Lovastatin therapy reduces low density lipoprotein apoB levels in subjects with combined hyperlipidemia by reducing the production of apoB-containing lipoproteins: implications for the pathophysiology of apoB production.

1990 • 210 citations

Familial combined hyperlipidaemia linked to the apolipoprotein AI–CIII–AIV gene cluster on chromosome 11q23q–q24

1991 • 188 citations

Pravastatin and gemfibrozil alone and in combination for the treatment of hypercholesterolemia

1993 • 166 citations

Role of triglycerides in coronary artery disease: Lessons from the prospective cardiovascular Münster study

1992 • 155 citations

Combination Drug Therapy for Familial Combined Hyperlipidemia

1988 • 127 citations

Pravastatin therapy in primary moderate hypercholesterolaemia: changes in metabolism of apolipoprotein B‐containing lipoproteins

1990 • 118 citations

Pravastatin

1991 • 117 citations

Mechanisms of HDL reduction after probucol. Changes in HDL subfractions and increased reverse cholesteryl ester transfer.

1989 • 113 citations

Reverse cholesterol transport: Physiology and pharmacology

1991 • 112 citations

Low density lipoprotein metabolism in familial combined hyperlipidemia. Mechanism of the multiple lipoprotein phenotypic expression.

1984 • 100 citations

Effects of lovastatin therapy on very-low-density lipoprotein triglyceride metabolism in subjects with combined hyperlipidemia: Evidence for reduced assembly and secretion of triglyceride-rich lipoproteins

1992 • 91 citations

A multicenter comparison of the effects of simvastatin and fenofibrate therapy in severe primary hypercholesterolemia, with particular emphasis on lipoproteins defined by their apolipoprotein composition

1992 • 78 citations

Tissue selectivity of hydroxymethylglutaryl coenzyme a (HMG CoA) reductase inhibitors

1993 • 73 citations

Bimodality of plasma apolipoprotein B levels in familial combined hyperlipidemia

1992 • 70 citations

Simvastatin improves chylomicron remnant removal in familial combined hyperlipidemia without changing chylomicron conversion

1993 • 69 citations

Familial combined hyperlipidaemia: Use of stable isotopes to demonstrate overproduction of very low‐density lipoprotein apolipoprotein B by the liver

1990 • 69 citations

Ciprofibrate therapy normalises the atherogenic low-density lipoprotein subspecies profile in combined hyperlipidemia

1993 • 58 citations

Effect of pravastatin, an HMG CoA reductase inhibitor, and cholestyramine, a bile acid sequestrant, on lipoprotein particles defined by their apolipoprotein composition

1990 • 55 citations

Apolipoprotein AIMilano. Partial lecithin: Cholesterol acyltransferase deficiency due to low levels of a functional enzyme

1990 • 43 citations

Effects of storage on the distribution of high density lipoprotein subfractions in human sera

1985 • 39 citations

Comparison of lovastatin and probucol in treatment of familial and non-familial hypercholesterolemia: different effects on lipoprotein profiles

1988 • 33 citations

Effect of simvastatin on the apparent size of LDL particles in patients with type IIB hyperlipoproteinemia

1991 • 27 citations

Low density lipoprotein metabolism in familial combined hyperlipidemia and familial hypercholesterolemia: Kinetic analysis using an integrated model

1986 • 26 citations

Isoelectric focusing of apolipoproteins in immobilized pH gradients: Improved determination of apolipoprotein Ephenotypes

1988 • 24 citations

Characterization of plasma lipids and lipoproteins in cholesteryl ester storage disease

1985 • 20 citations

Apolipoprotein A-II modulates HDL remodeling in plasma

1992 • 20 citations

Significant increase of high-density lipoprotein2-cholesterol under prolonged simvastatin treatment

1991 • 20 citations