MRI techniques to monitor MS evolution

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis

2001 • 6,888 citations

Axonal Transection in the Lesions of Multiple Sclerosis

1998 • 4,007 citations

Estimation of metabolite concentrations from localized in vivo proton NMR spectra

1993 • 3,535 citations

Modeling tracer kinetics in dynamic Gd‐DTPA MR imaging

1997 • 1,460 citations

Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions

2001 • 1,377 citations

Cortical lesions in multiple sclerosis

1999 • 767 citations

Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS

1999 • 728 citations

Axonal loss in multiple sclerosis lesions: Magnetic resonance imaging insights into substrates of disability

1999 • 713 citations

Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis

1998 • 652 citations

Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies

1991 • 625 citations

Spinal cord atrophy and disability in multiple sclerosis

1996 • 618 citations

Diffusion tensor magnetic resonance imaging in multiple sclerosis

2001 • 543 citations

Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesions

1994 • 534 citations

Inflammatory central nervous system demyelination: Correlation of magnetic resonance imaging findings with lesion pathology

1997 • 517 citations

Evidence of Axonal Damage in the Early Stages of Multiple Sclerosis and Its Relevance to Disability

2001 • 507 citations

Axonal damage correlates with disability in patients with relapsing- remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy study

1998 • 499 citations

Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis

1999 • 490 citations

Imaging axonal damage of normal-appearing white matter in multiple sclerosis

1998 • 483 citations

Progressive cerebral atrophy in multiple sclerosis A serial MRI study

1996 • 482 citations

Loss of connectivity in Alzheimer's disease: an evaluation of white matter tract integrity with colour coded MR diffusion tensor imaging

2000 • 470 citations

Accumulation of hypointense lesions ("black holes") on T ₁ spin-echo MRI correlates with disease progression in multiple sclerosis

1996 • 451 citations

Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis

2000 • 404 citations

Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis

1993 • 378 citations

Correlation of magnetization transfer ration with clinical disability in multiple sclerosis

1994 • 335 citations

Evidence for adaptive functional changes in the cerebral cortex with axonal injury from multiple sclerosis

2000 • 313 citations

Magnetisation transfer ratio and mean diffusivity of normal appearing white and grey matter from patients with multiple sclerosis

2001 • 289 citations

Patterns of disease activity in multiple sclerosis: clinical and magnetic resonance imaging study.

1990 • 285 citations

The motor cortex shows adaptive functional changes to brain injury from multiple sclerosis

2000 • 269 citations

Relation between MR abnormalities and patterns of cognitive impairment in multiple sclerosis

1998 • 268 citations

Patterns of lesion development in multiple sclerosis: longitudinal observations with T1-weighted spin-echo and magnetization transfer MR.

1998 • 266 citations

Mean diffusivity and fractional anisotropy histograms of patients with multiple sclerosis.

2001 • 238 citations

Quantitative volumetric magnetization transfer analysis in multiple sclerosis: Estimation of macroscopic and microscopic disease burden

1996 • 236 citations

Comparison of MS clinical phenotypes using conventional and magnetization transfer MRI

1999 • 234 citations

Adaptive functional changes in the cerebral cortex of patients with nondisabling multiple sclerosis correlate with the extent of brain structural damage

2002 • 222 citations

Biochemical alterations in multiple sclerosis lesions and normal‐appearing white matter detected by in vivo ³¹P and ¹H spectroscopic imaging

1994 • 219 citations

A longitudinal MRI study of histopathologically defined hypointense multiple sclerosis lesions

2001 • 215 citations

Magnetization transfer and multicomponent T2 relaxation measurements with histopathologic correlation in an experimental model of MS

2000 • 208 citations

In vivo macrophage activity imaging in the central nervous system detected by magnetic resonance

1999 • 208 citations

A serial study of new MS lesions and the white matter from which they arise

1998 • 201 citations

Use of proton magnetic resonance spectroscopy for monitoring disease progression in multiple sclerosis

1994 • 197 citations

Changes in the normal appearing brain tissue and cognitive impairment in multiple sclerosis

2000 • 195 citations

Total brain N -acetylaspartate

2000 • 188 citations

Pathologic damage in MS assessed by diffusion-weighted and magnetization transfer MRI

2000 • 185 citations

A magnetization transfer histogram study of normal-appearing brain tissue in MS

2000 • 180 citations

Diffusion-weighted MR imaging of the hippocampus and temporal white matter in Alzheimer's disease

1998 • 180 citations

Quantification of tissue damage in AD using diffusion tensor and magnetization transfer MRI

2001 • 178 citations

Correlation of volumetric magnetization transfer imaging with clinical data in MS

1998 • 170 citations

Assessment of lesion pathology in multiple sclerosis using quantitative MRI morphometry and magnetic resonance spectroscopy

1996 • 170 citations

Guidelines for using quantitative measures of brain magnetic resonance imaging abnormalities in monitoring the treatment of multiple sclerosis

1998 • 166 citations

Lysolecithin-induced demyelination in primates: preliminary in vivo study with MR and magnetization transfer.

1995 • 158 citations

Short-term brain volume change in relapsing-remitting multiple sclerosis: Effect of glatiramer acetate and implications

2001 • 156 citations

Diffusion imaging of the spinal cord in vivo: Estimation of the principal diffusivities and application to multiple sclerosis

2000 • 147 citations

Magnetization transfer imaging to monitor the evolution of MS

2000 • 146 citations

Dyke Award paper. MR of wallerian degeneration in the feline visual system: characterization by magnetization transfer rate with histopathologic correlation.

1994 • 140 citations

Comparison of ultrasmall particles of iron oxide (USPIO)-enhanced T2-weighted, conventional T2-weighted, and gadolinium-enhanced T1-weighted MR images in rats with experimental autoimmune encephalomyelitis.

1999 • 140 citations

Linomide in relapsing and secondary progressive MS

2000 • 135 citations

A conventional and magnetization transfer MRI study of the cervical cord in patients with MS

2000 • 134 citations

A longitudinal study of T1 hypointense lesions in relapsing MS

2000 • 134 citations

Hypointense Lesions on T1-Weighted Spin-Echo Magnetic Resonance Imaging

2001 • 133 citations

Magnetization Transfer Ratio Histogram Analysis of Gray Matter in Relapsing-remitting Multiple Sclerosis

2001 • 131 citations

Whole brain volume changes in patients with progressive MS treated with cladribine

2000 • 123 citations

Whole-brain diffusion MR histograms differ between MS subtypes

2000 • 120 citations

A multicenter measurement of magnetization transfer ratio in normal white matter

1999 • 112 citations

Early structural changes in acute MS lesions assessed by serial magnetization transfer studies

1998 • 108 citations

Demyelinating plaques in relapsing-remitting and secondary-progressive multiple sclerosis: assessment with diffusion MR imaging.

2000 • 105 citations

Long-term changes of magnetization transfer-derived measures from patients with relapsing-remitting and secondary progressive multiple sclerosis.

1999 • 102 citations

MR proton spectroscopy in multiple sclerosis.

1992 • 101 citations

Correlates of MS disability assessed in vivo using aggregates of MR quantities

2001 • 92 citations

Magnetization Transfer Imaging of Diffuse Axonal Injury Following Experimental Brain Injury in the Pig: Characterization by Magnetization Transfer Ratio with Histopathologic Correlation

1996 • 90 citations

Diffusion‐weighted imaging of the human optic nerve: A New approach to evaluate optic neuritis in multiple sclerosis

1997 • 88 citations

Insulin Secretion and Acetylcholinesterase Activity in Monosodium <i>L</i>-Glutamate-Induced Obese Mice

2000 • 85 citations

Relative contributions of brain and cervical cord pathology to multiple sclerosis disability: a study with magnetisation transfer ratio histogram analysis

2000 • 83 citations

Magnetization transfer ratios in multiple sclerosis lesions enhancing after different doses of gadolinium

1998 • 78 citations

Evaluation of multiple sclerosis by ¹H spectroscopic imaging at 4.1 T

1996 • 77 citations

Correlations between clinical and MRI involvement in multiple sclerosis: assessment using T1, T2 and MT histograms

1999 • 71 citations

Magnetic resonance imaging, magnetisation transfer imaging, and diffusion weighted imaging correlates of optic nerve, brain, and cervical cord damage in Leber's hereditary optic neuropathy

2001 • 70 citations

Characteristics of chronic MS lesions in the cerebrum, brainstem, spinal cord, and optic nerve on T1‐‐‐weighted MRI

1998 • 69 citations

Magnetization-transfer histogram analysis of the cervical cord in patients with multiple sclerosis.

1999 • 54 citations

Placebo-controlled clinical trials in multiple sclerosis: ethical considerations. National Multiple Sclerosis Society (USA) Task Force on Placebo-Controlled Clinical Trials in MS.

2001 • 52 citations

Magnetization transfer ratios of multiple sclerosis lesions with variable durations of enhancement

1998 • 51 citations

Linking structural, metabolic and functional changes in multiple sclerosis

2001 • 51 citations

Placebo‐controlled clinical trials in multiple sclerosis: Ethical considerations

2001 • 39 citations

Reproducibility of magnetization transfer ratio histogram-derived measures of the brain in healthy volunteers.

2000 • 33 citations

Multiple sclerosis: a white matter disease with associated gray matter damage

2001 • 31 citations

Multiple sclerosis: more than inflammation and demyelination

2001 • 31 citations

Access www.neurology.org now for full-text articles

2000 • 31 citations

A Novel Nonsense Mutation of the KAL Gene in Two Brothers withKallmann Syndrome

2000 • 28 citations

Exacerbation of postural tremor with emergence of parkinsonism after treatment with neuroleptic drugs.

1995 • 16 citations

Transcriptional activation of the non-muscle, full-length dystrophin isoforms in Duchenne muscular dystrophy skeletal muscle

2001 • 11 citations

Axonal Injury and Disability in Multiple Sclerosis: Magnetic Resonance Spectroscopy as a Measure of Dynamic Pathological Change in White Matter

2001 • 10 citations

Calendar

1999 • 7 citations

Optimization and Standardization of Magnetic Resonance Spectroscopy Techniques for Multicenter Longitudinal Multiple Sclerosis Studies

2001 • 1 citations