Role of ATP7B in biliary copper excretion in a human hepatoma cell line and normal rat hepatocytes

ACIDIFICATION OF THE ENDOCYTIC AND EXOCYTIC PATHWAYS

1986 • 1,977 citations

The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene

1993 • 1,905 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

The Liver: Biology and Pathobiology.

1983 • 1,628 citations

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.

1986 • 1,588 citations

The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

1993 • 1,345 citations

Copper biochemistry and molecular biology

1996 • 1,171 citations

PROGRESSIVE LENTICULAR DEGENERATION: A FAMILIAL NERVOUS DISEASE ASSOCIATED WITH CIRRHOSIS OF THE LIVER

1912 • 1,117 citations

The mannose 6-phosphate receptor and the biogenesis of lysosomes

1988 • 846 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

1992 • 741 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

Immunocytochemical localization of galactosyltransferase in HeLa cells: codistribution with thiamine pyrophosphatase in trans-Golgi cisternae.

1982 • 617 citations

Mapping, cloning and genetic characterization of the region containing the Wilson disease gene

1993 • 489 citations

Identification of two lysosomal membrane glycoproteins.

1985 • 475 citations

Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substances.

1981 • 424 citations

TIP47: A Cargo Selection Device for Mannose 6-Phosphate Receptor Trafficking

1998 • 386 citations

Recycling of Golgi-resident Glycosyltransferases through the ER Reveals a Novel Pathway and Provides an Explanation for Nocodazole-induced Golgi Scattering

1998 • 326 citations

Biochemical Characterization of the Wilson Disease Protein and Functional Expression in the Yeast Saccharomyces cerevisiae

1997 • 324 citations

Cellular Copper Transport

1995 • 281 citations

Retrograde Transport of Golgi-localized Proteins to the ER

1998 • 228 citations

Functional expression of the Wilson disease protein reveals mislocalization and impaired copper-dependent trafficking of the common H1069Q mutation

1998 • 225 citations

Restoration of Holoceruloplasmin Synthesis in LEC Rat after Infusion of Recombinant Adenovirus Bearing WND cDNA

1998 • 167 citations

Localization of the Wilson’s disease protein product to mitochondria

1998 • 130 citations

Copper and Zinc

2013 • 129 citations

Lysosomal Defect of Hepatic Copper Excretion in Wilson's Disease (Hepatolenticular Degeneration)

1973 • 123 citations

Wilson's disease: Current status

1992 • 119 citations

Biliary copper excretion by hepatocyte lysosomes in the rat. Major excretory pathway in experimental copper overload.

1989 • 114 citations

Redistribution of mannose-6-phosphate receptors induced by tunicamycin and chloroquine.

1984 • 114 citations

Two forms of Wilson disease protein produced by alternative splicing are localized in distinct cellular compartments

1997 • 100 citations

Phosphorylation of the cation-independent mannose 6-phosphate receptor is closely associated with its exit from the trans-Golgi network.

1993 • 85 citations

Biliary excretion of copper in LEC rat after introduction of copper transporting P‐type ATPase, ATP7B

1999 • 83 citations

Regulation and translocation of ATP-dependent apical membrane proteins in rat liver

1997 • 81 citations

Intracellular distribution of the Wilson's disease gene product (atpase7b) afterin vitro andin vivo exogenous expression in hepatocytes from the LEC rat, an animal model of Wilson's disease

1998 • 71 citations

Predictive testing for Wilson's disease using tightly linked and flanking DNA markers

1991 • 50 citations

Biliary Copper Excretion in Acutely and Chronically Copper-loaded Rats

1993 • 48 citations

A protein-specific monoclonal antibody to rat liver beta 1-->4 galactosyltransferase and its application to immunohistochemistry.

1994 • 39 citations

Bafilomycin A1, a specific inhibitor of vacuolar-type H+-ATPases, inhibits the receptor-mediated endocytosis of asialoglycoproteins in isolated rat hepatocytes

1996 • 33 citations

Purification and Characterization of an 85 kDa Sialoglycoprotein in Liver Lysosomal Membranes1

1992 • 31 citations

Role of cytoskeleton and acidification of endocytic compartment in asialoglycoprotein metabolism in isolated rat hepatocyte couplets

1995 • 17 citations

Two forms of Wilson disease protein produced by alternative splicing are localized in distinct cellular compartments

1998 • 13 citations