The effects of inhibitors of sarcoplasmic reticulum function on the systolic Ca2+ transient in rat ventricular myocytes.

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum

1983 • 1,884 citations

Activation of Calcium Entry by the Tumor Promoter Thapsigargin in Parotid Acinar Cells

1989 • 887 citations

Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum.

1986 • 710 citations

Ryanodine modifies conductance and gating behavior of single Ca2+ release channel

1987 • 548 citations

Rapid calcium release from cardiac sarcoplasmic reticulum vesicles is dependent on Ca2+ and is modulated by Mg2+, adenine nucleotide, and calmodulin.

1987 • 489 citations

The Stimulation of Calcium Transport in Cardiac Sarcoplasmic Reticulum by Adenosine 3′:5′-Monophosphate-dependent Protein Kinase

1974 • 398 citations

Single cardiac sarcoplasmic reticulum Ca2+-release channel: activation by caffeine

1989 • 288 citations

Mechanisms of caffeine activation of single calcium‐release channels of sheep cardiac sarcoplasmic reticulum.

1990 • 279 citations

Measurement of mitochondrial free Ca2+ concentration in living single rat cardiac myocytes

1991 • 277 citations

Influence of Caffeine and other Methylxanthines on Mechanical Properties of Isolated Mammalian Heart Muscle: EVIDENCE FOR A DUAL MECHANISM OF ACTION

1972 • 262 citations

Calcium transients in mammalian ventricular muscle

1980 • 236 citations

Ca2+ binding effects on protein conformation and protein interactions of canine cardiac calsequestrin.

1988 • 218 citations

Regulation of Steady State Filling in Sarcoplasmic Reticulum

1989 • 202 citations

The effects of metabolic inhibition on intracellular calcium and pH in isolated rat ventricular cells.

1989 • 195 citations

Relaxation of rabbit ventricular muscle by Na-Ca exchange and sarcoplasmic reticulum calcium pump. Ryanodine and voltage sensitivity.

1989 • 179 citations

Drug action of thapsigargin on the Ca2+ pump protein of sarcoplasmic reticulum.

1991 • 162 citations

The role of [Ca2+]i and [Ca2+] sensitization in the caffeine contracture of rat myocytes: measurement of [Ca2+]i and [caffeine]i.

1990 • 157 citations

Sodium‐calcium exchange in guinea‐pig cardiac cells: exchange current and changes in intracellular Ca2+.

1989 • 155 citations

A mechanism for the effects of caffeine on Ca2+ release during diastole and systole in isolated rat ventricular myocytes.

1990 • 110 citations

Ryanodine releases calcium from sarcoplasmic reticulum in calcium‐tolerant rat cardiac myocytes.

1987 • 104 citations

Total and free myoplasmic calcium during a contraction cycle: x‐ray microanalysis in guinea‐pig ventricular myocytes.

1991 • 94 citations

Excitation-contraction coupling in cardiac Purkinje fibers. Effects of caffeine on the intracellular [Ca2+] transient, membrane currents, and contraction.

1984 • 93 citations

Sarcoplasmic reticulum interacts with the Ca(2+) indicator precursor fura-2-AM

1986 • 83 citations

Effects of rapid application of caffeine on intracellular calcium concentration in ferret papillary muscles.

1988 • 59 citations

Effects of ryanodine on intracellular Ca2+ transients in mammalian cardiac muscle.

1985 • 50 citations

Changes of intracellular [Ca2+] during refilling of sarcoplasmic reticulum in rat ventricular and vascular smooth muscle.

1993 • 38 citations

The Contribution of Na‐Ca Exchange to Relaxation in Mammalian Cardiac Muscle^a

1991 • 28 citations