Both Microtubules and Actin Filaments Are Required for Efficient Postendocytotic Traffic of the Polymeric Immunoglobulin Receptor in Polarized Madin-Darby Canine Kidney Cells

Effects of cytochalasin and phalloidin on actin.

1987 • 1,989 citations

On the Crawling of Animal Cells

1993 • 1,020 citations

Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro.

1989 • 588 citations

Action of cytochalasin D on cytoskeletal networks.

1982 • 581 citations

Organization, Chemistry, and Assembly of the Cytoskeletal Apparatus of the Intestinal Brush Border

1985 • 525 citations

The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles.

1991 • 471 citations

Actin microfilaments play a critical role in endocytosis at the apical but not the basolateral surface of polarized epithelial cells.

1993 • 438 citations

Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes.

1994 • 384 citations

Unconventional Myosins

1995 • 362 citations

Pancreatic Beta-Cell Web: Its Possible Role in Insulin Secretion

1972 • 360 citations

Intracellular receptor sorting during endocytosis: Comparative immunoelectron microscopy of multiple receptors in rat liver

1984 • 359 citations

Intestinal absorptive cell tight junctions are linked to cytoskeleton

1987 • 343 citations

Correlation between effects of 24 different cytochalasins on cellular structures and cellular events and those on actin in vitro

1982 • 316 citations

Interactions between actin filaments and between actin filaments and membranes in quick-frozen and deeply etched hair cells of the chick ear.

1982 • 310 citations

Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells

1990 • 299 citations

An autonomous signal for basolateral sorting in the cytoplasmic domain of the polymeric immunoglobulin receptor

1991 • 298 citations

Organization of actin, myosin, and intermediate filaments in the brush border of intestinal epithelial cells.

1982 • 260 citations

Organization of the actin filament cytoskeleton in the intestinal brush border: a quantitative and qualitative immunoelectron microscope study.

1988 • 246 citations

Role of microtubules in polarized delivery of apical membrane proteins to the brush border of the intestinal epithelium.

1989 • 240 citations

Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells

1994 • 232 citations

Microtubules, membrane traffic, and cell organization

1990 • 229 citations

Microtubular organization and its involvement in the biogenetic pathways of plasma membrane proteins in Caco-2 intestinal epithelial cells.

1991 • 229 citations

Suppression of a myosin defect by a kinesin-related gene

1992 • 210 citations

Microtubule-acting drugs lead to the nonpolarized delivery of the influenza hemagglutinin to the cell surface of polarized Madin-Darby canine kidney cells.

1987 • 210 citations

Molecular motors are differentially distributed on Golgi membranes from polarized epithelial cells.

1994 • 208 citations

Protein trafficking and polarity in kidney epithelium: from cell biology to physiology

1996 • 196 citations

Golgi-derived vesicles from developing epithelial cells bind actin filaments and possess myosin-I as a cytoplasmically oriented peripheral membrane protein.

1993 • 192 citations

Actin filaments facilitate two steps of endocytosis

1996 • 187 citations

Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric G protein sensitive passage through the apical endosome

1994 • 186 citations

Involvement of microtubule motors in basolateral and apical transport in kidney cells

1994 • 183 citations

Effect of nocodazole on vesicular traffic to the apical and basolateral surfaces of polarized MDCK cells.

1990 • 167 citations

Differential microtubule requirements for transcytosis in MDCK cells.

1990 • 159 citations

Organization and function of the cytoskeleton in polarized epithelial cells: a component of the protein sorting machinery

1994 • 156 citations

Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis.

1990 • 145 citations

Regulation of protein traffic in polarized epithelial cells.

1995 • 138 citations

Inhibition of apical but not basolateral endocytosis of ricin and folate in Caco-2 cells by cytochalasin D

1994 • 130 citations

Kinesin-II, a membrane traffic motor in axons, axonemes, and spindles.

1996 • 127 citations

Postendocytotic sorting of the ligand for the polymeric immunoglobulin receptor in Madin-Darby canine kidney cells.

1989 • 116 citations

Wortmannin, an Inhibitor of Phosphoinositide 3-Kinase, Inhibits Transcytosis in Polarized Epithelial Cells

1995 • 112 citations

Microtubule perturbation retards both the direct and the indirect apical pathway but does not affect sorting of plasma membrane proteins in intestinal epithelial cells (Caco-2).

1990 • 108 citations

Membrane-cytoskeleton dynamics in rat parietal cells: mobilization of actin and spectrin upon stimulation of gastric acid secretion.

1989 • 100 citations

ATP and cytosol requirements for transferrin recycling in intact and disrupted MDCK cells.

1990 • 90 citations

Chapter 13 Expression and Analysis of the Polymeric Immunoglobulin Receptor in Madin—Darby Canine Kidney Cells Using Retroviral Vectors

1989 • 80 citations

Reconstitution of transcytosis in SLO-permeabilized MDCK cells: existence of an NSF-dependent fusion mechanism with the apical surface of MDCK cells.

1996 • 80 citations

Binding of exocytic vesicles from MDCK cells to microtubules in vitro

1990 • 72 citations

Antidiuretic hormone and exocytosis: lessons from neurosecretion

1994 • 72 citations

Cytochalasin D does not produce net depolymerization of actin filaments in HEp-2 cells

1980 • 68 citations

Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis.

1996 • 63 citations

Transcytosis of the polymeric immunoglobulin receptor is regulated in multiple intracellular compartments.

1994 • 63 citations

What are the basic functions of microfilaments? Insights from studies in budding yeast.

1994 • 59 citations

Membrane motility mediated by unconventional myosin

1994 • 52 citations

Apical and basolateral coated pits of MDCK cells differ in their rates of maturation into coated vesicles, but not in the ability to distinguish between mutant hemagglutinin proteins with different internalization signals.

1995 • 43 citations

The effect of vasopressin on the cytoskeleton of the epithelial cell

1993 • 39 citations

Distribution of microtubules within the intestinal terminal web as revealed by quick-freezing and cryosubstitution.

1986 • 35 citations

Zinc alters actin filaments in Madin-Darby canine kidney cells

1992 • 17 citations

Do unconventional myosins exert functions in dynamics of membrane compartments?

1992 • 16 citations