Dynamic instability of chromosomes and genomes

The Clonal Evolution of Tumor Cell Populations

1976 • 6,310 citations

The Genetics and Biology of Drosophila

1978 • 3,910 citations

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

1988 • 2,281 citations

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

1985 • 1,930 citations

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

1990 • 829 citations

A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite.

1989 • 659 citations

Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes

1990 • 614 citations

STRUCTURE AND FUNCTION OF TELOMERES

1989 • 604 citations

Localization of cytoplasmic dynein to mitotic spindles and kinetochores

1990 • 508 citations

Cytoplasmic dynein is localized to kinetochores during mitosis

1990 • 486 citations

The Formation, Structure, and Composition of the Mammalian Kinetochore and Kinetochore Fiber

1982 • 428 citations

Sites of microtubule assembly and disassembly in the mitotic spindle

1986 • 410 citations

CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase.

1991 • 384 citations

Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy

1990 • 340 citations

A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere

1991 • 313 citations

The centromere-kinetochore complex: a repeat subunit model.

1991 • 283 citations

Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis.

1989 • 251 citations

Addition of telomere-associated HeT DNA sequences “heals” broken chromosome ends in Drosophila

1990 • 245 citations

Microtubule depolymerization promotes particle and chromosome movement in vitro.

1991 • 215 citations

The motor for poleward chromosome movement in anaphase is in or near the kinetochore.

1989 • 202 citations

Two different microtubule-based motor activities with opposite polarities in kinetochores

1991 • 202 citations

Lamins A and C bind and assemble at the surface of mitotic chromosomes.

1990 • 198 citations

Normal diploid human and rodent cells lack a detectable frequency of gene amplification.

1990 • 179 citations

THE STRUCTURE AND FUNCTION OF YEAST CENTROMERES

1985 • 164 citations

A structural basis for variegating position effects

1984 • 160 citations

Microtubule dynamics and chromosome motion visualized in living anaphase cells.

1988 • 147 citations

Injection of anticentromere antibodies in interphase disrupts events required for chromosome movement at mitosis.

1990 • 147 citations

Telomere telomere recombination provides an express pathway for telomere acquisition

1990 • 146 citations

Microinjected centromere [corrected] kinetochore antibodies interfere with chromosome movement in meiotic and mitotic mouse oocytes [published erratum appears in J Cell Biol 1990 Dec;111(6 Pt 1):following 2800]

1990 • 109 citations

Identification of DNA regions required for mitotic and meiotic functions within the centromere of Schizosaccharomyces pombe chromosome I.

1991 • 76 citations

Nucleosome depletion alters the chromatin structure of Saccharomyces cerevisiae centromeres.

1990 • 66 citations

Heterochromatin: junk or collectors item?

1990 • 66 citations

Nonrandom Distribution of Long Mono- and Dinucleotide Repeats in Drosophila Chromosomes: Correlations with Dosage Compensation, Heterochromatin, and Recombination

1989 • 66 citations

Nonrandom distribution of long mono- and dinucleotide repeats in Drosophila chromosomes: correlations with dosage compensation, heterochromatin, and recombination.

1989 • 51 citations