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Population pharmacokinetics of hydroxyurea in cancer patients

Data up to Jan 2025

Published1995
Citations40
References20

Total Citations Per Year

Abstract

References (20)

Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia [see comments]

1992 • 422 citations

Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia [see comments]

1992 • 296 citations

On the practical identifiability of microbial growth models incorporating Michaelis-Menten type nonlinearities

1982 • 285 citations

Effect of hydroxyurea on ribonucleotide reductase

1968 • 196 citations

Hydroxyurea. I. Acute cell death in proliferating tissues in rats.

1967 • 160 citations

Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production

1986 • 122 citations

Practical identifiability of growth and substrate consumption models

1977 • 100 citations

Studies of hydroxyurea administered by continuous infusion. Toxicity, pharmacokinetics, and cell synchronization

1980 • 83 citations

Prolonged systemic delivery of peptide drugs by long-circulating liposomes: illustration with vasopressin in the Brattleboro rat.

1992 • 81 citations

Transcatheter arterial chemoembolization for hepatocellular carcinoma

1989 • 55 citations

The distribution, excretion and metabolism of hydroxyurea-C14.

1965 • 55 citations

Determination of hydroxyurea in mammalian tissues and blood.

1971 • 54 citations

Hydroxyurea (NSC-32065) in biologic fluids: dose-concentration relationship.

1965 • 51 citations

High-dose cyclophosphamide, thiotepa and hydroxyurea with autologous hematopoietic stem cell rescue: an effective consolidation chemotherapy regimen for early metastatic breast cancer.

1994 • 34 citations

Phase 1 study of high-dose hydroxyurea in lung cancer

1988 • 33 citations

Mathematical properties of compartment models with Michaelis-Menton type elimination

1980 • 32 citations

The enzymatic reduction of hydroxyurea to urea by mouse liver.

1970 • 25 citations

Hydroxyurea: Relationship between Toxicity and Centrally‐Induced Adrenal Activation

1990 • 19 citations

Hydroxyurea potentiation of the antineoplastic activity of cyclophosphamide and 4?-(9-acridinylamino)methanesulfon-M-anisidide (AMSA) in the brown Norway rat myelocytic leukemia model

1989 • 14 citations

Pharmacokinetics of hydroxyurea in the rat

1992 • 1 citations

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