Activity correlations in the phorbol ester series

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

Metabolism of [14C]arachidonic acid by human platelets

1976 • 453 citations

Cocarcinogenic principles from the seed oil of Croton tiglium and from other Euphorbiaceae.

1968 • 376 citations

Phorbol ester and diacylglycerol induce protein phosphorylation at tyrosine

1983 • 214 citations

Phorbol myristate acetate: a mitogen selective for a T-lymphocyte subpopulation.

1977 • 188 citations

Methods in Cancer Research

1956 • 163 citations

Phorbolesters — the Irritants and Cocarcinogens of Croton Tiglium L.

1974 • 138 citations

Structure-activity relationships in diterpene esters irritant and cocarcinogenic to mouse skin

1978 • 137 citations

Induction of expression and phosphorylation of the human interleukin 2 receptor by a phorbol diester.

1984 • 116 citations

THE TUMOR-PROMOTER PHORBOL ESTER (12-0-TETRADECANOYL-PHORBOL-13-ACETATE), A POTENT AGGREGATING AGENT FOR BLOOD PLATELETS

1974 • 113 citations

New toxic, irritant and cocarcinogenic diterpene esters from Euphorbiaceae and from Thymelaeaceae

1977 • 94 citations

Pro-Inflammatory, Tumour-Promoting and Anti-Tumour Diterpenes of the Plant Families Euphorbiaceae and Thymelaeaceae

1983 • 93 citations

The tigliane, daphnane and ingenane diterpenes, their chemistry, distribution and biological activities. A review.

1978 • 93 citations

Naturally Occurring Phorbol Esters

2018 • 86 citations

Stimulation of prostaglandin production in bone by phorbol diesters and melittin

1978 • 82 citations

The correlation of promotion of tumour growth and of induction of hyperplasia in epidermal two-stage carcinogenesis

1968 • 72 citations

Structure-activity Relations of Polyfunctional Diterpenes of the Daphnane Type. I. Revised Structure For Resiniferatoxin and Structure-activity Relations of Resini-feronol and Some of its Esters

1982 • 71 citations

ZUM WIRKUNGSMECHANISMUS COCARCINOGENER PFLANZENINHALTSSTOFFE

1972 • 65 citations

A BIOLOGICAL SCREEN OF SELECTED SPECIES OF THE GENUSEUPHORBIAFOR SKIN IRRITANT EFFECTS

1975 • 65 citations

An assay procedure for the comparative irritancy testing of esters in the tigliane and daphnane series

1979 • 60 citations

�ber die Wirkstoffe des Croton�ls

1966 • 51 citations

Degradation of different molecular species of phosphatidylinositol in thrombin-stimulated human platelets.

1983 • 51 citations

Multiple effects of dexamethasone on protein synthesis and hyperplasia caused by a tumor promoter.

1973 • 49 citations

�ber die Wirkstoffe des Croton�ls

1965 • 48 citations

Ultrastructural features on the platelet response to phorbol myristate acetate.

1974 • 43 citations

Pretreatment with croton oil, DNA synthesis. And carcinogenesis by carcinogen followed by croton oil

1967 • 43 citations

Investigations into the skin-irritant properties of resiniferonol ortho esters

1979 • 41 citations

X‐ray Structure Analysis of Neophorbol

1967 • 41 citations

Skin irritant effects of esters of phorbol and related polyols

1980 • 35 citations

Acrylamide gel electrophoresis studies of the incorporation of cytidine- 3 H into mouse skin RNA at early times after treatment with phorbol esters.

1972 • 32 citations

Cytochemical electron microscopic studies of the action of phorbol myristate acetate on platelets.

1974 • 27 citations

Quantitative correlation between in vitro and in vivo activities of phorbol esters.

1979 • 26 citations

New Phorbol and Deoxyphorbol Esters: Isolation and Relative Potencies in Inducing Platelet Aggregation and Erythema of Skin

1983 • 24 citations

Studies on the mechanism of action of 12-deoxyphorbolphenylacetate, a potent platelet aggregating tigliane ester

1981 • 22 citations

The irritant toxins of Blue Euphorbia (Euphorbia coerulescens Haw.)

1978 • 17 citations

Structure activity relationships of 12-deoxyphorbol esters on human platelets

1980 • 17 citations

[On the active substances in croton oil. 6. Inflammation tests on the mouse ear].

1966 • 16 citations

Tumor-promoting and nonpromoting proinflammatory esters act as human lymphocyte mitogens with different sensitivities to inhibition by cyclosporin A.

1983 • 11 citations

Activation of Protein Kinase C By Tumour-Promoting and Non-Promoting Phorbol Esters

1985 • 10 citations

Inhibition of Erythema Induced by Pro-inflammatory Esters of 12-Deoxyphorbol

1981 • 10 citations

Stimulation of prostaglandin production, deacylation of lipids and morphological changes by tumor-promoting phorbol-12,13-diesters and adriamycin in MDCK cells: Effect of cycloheximide, indomethacin and hydrocortisone on these stimulations

1978 • 10 citations

Vascular changes in rabbit skin induced by proinflammatory phorbol and 12-deoxyphorbol esters

1981 • 9 citations

Structural correlations of phorbol-ester-induced stimulation of PGE2 production by human rheumatoid synovial cells

1985 • 8 citations

The effect of daphnane esters on platelet aggregation and erythema of the mouse ear

1980 • 6 citations

Release of an Aggregating Substance by Human Platelets in Response to Phorbol-Ester Stimulation

1982 • 1 citations