Gelsolin Activates DNase Iin Vitroand in Cystic Fibrosis Sputum

Atomic structure of the actin: DNase I complex

1990 • 1,897 citations

Atomic model of the actin filament

1990 • 1,657 citations

Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death).

1993 • 554 citations

Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells.

1993 • 341 citations

A Preliminary Study of Aerosolized Recombinant Human Deoxyribonuclease I in the Treatment of Cystic Fibrosis

1992 • 203 citations

Actin-gelsolin interactions. Evidence for two actin-binding sites.

1984 • 156 citations

Deoxyribonuclease I in mammalian tissues. Specificity of inhibition by actin.

1981 • 150 citations

Probing actin polymerization by intermolecular cross-linking.

1988 • 118 citations

Interaction of plasma gelsolin with G-actin and F-actin in the presence and absence of calcium ions.

1985 • 105 citations

Comparative two-dimensional gel analysis and microsequencing identifies gelsolin as one of the most prominent downregulated markers of transformed human fibroblast and epithelial cells.

1990 • 99 citations

Mbh 1: a novel gelsolin/severin-related protein which binds actin in vitro and exhibits nuclear localization in vivo.

1991 • 87 citations

Two of the three actin‐binding domains of gelsolin bind to the same subdomain of actin Implications for capping and severing mechanisms

1991 • 73 citations

The actin monomers in the ternary gelsolin: 2 actin complex are in an antiparallel orientation

1993 • 72 citations

12 Deoxyribonuclease I

1971 • 51 citations

A 90 000-dalton actin-binding protein from platelets comparison with villin and plasma brevin

1982 • 46 citations

Rate constants and equilibrium constants for binding of actin to the 1:1 gelsolin‐actin complex

1991 • 28 citations

Effects of serum vitamin‐D‐binding protein on actin in the presence of plasma gelsolin

1986 • 19 citations