A study of the antiviral mechanism of action of 2-deoxy-d-glucose: Normally glycosylated proteins are not strictly required for herpes simplex virus attachment but increase viral penetration and infectivity

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Methods in Enzymology , Vol

1966 • 26,261 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

[105] Determination of DNA concentration with diphenylamine

1968 • 1,300 citations

Proteins Specified by Herpes Simplex Virus V. Purification and Structural Proteins of the Herpesvirion

1972 • 565 citations

Production of mammalian somatic cell hybrids by means of polyethylene glycol treatment

1975 • 549 citations

Synchronised transmembrane insertion and glycosylation of a nascent membrane protein

1977 • 529 citations

Proteins Specified by Herpes Simplex Virus XII. The Virion Polypeptides of Type 1 Strains

1974 • 503 citations

Size, Composition, and Structure of the Deoxyribonucleic Acid of Herpes Simplex Virus Subtypes 1 and 2

1971 • 380 citations

Membrane proteins specified by herpes simplex viruses. III. Role of glycoprotein VP7(B2) in virion infectivity

1979 • 364 citations

An Improved Technique for Obtaining Enhanced Infectivity with Herpes Simplex Virus Type 1 DNA

1976 • 304 citations

Membrane proteins specified by herpes simplex viruses. I. Identification of four glycoprotein precursors and their products in type 1-infected cells

1976 • 296 citations

Sulfonyl Fluorides as Inhibitors of Esterases. II. Formation and Reactions of Phenylmethanesulfonyl α-Chymotrypsin^*

1964 • 294 citations

Cell fusion induced by herpes simplex virus is promoted and suppressed by different viral glycoproteins.

1977 • 249 citations

A virion-associated glycoprotein essential for infectivity of herpes simplex virus type 1

1981 • 208 citations

Phospholipase A. I. Isolation and characterization of two enzymes from Crotalus adamanteus venom

1969 • 200 citations

Effects of 2-deoxy-d-glucose on herpes simplex virus replication

1973 • 146 citations

Inhibition of the Multiplication of Enveloped RNA-viruses by Glucosamine and 2-Deoxy-D-Glucose

1972 • 140 citations

The Course of Untreated Recurrent Genital Herpes Simplex Infection in 27 Women

1981 • 119 citations

Chapter 18 Induction of Mammalian Somatic Cell Hybridization by Polyethylene Glycol

1977 • 111 citations

Interference with glycosylation of glycoproteins. Inhibition of formation of lipid-linked oligosaccharides in vivo

1979 • 108 citations

Effect of 2-deoxy-d-glucose on the multiplication of semliki forest virus and the reversal of the block by mannose

1973 • 106 citations

Inhibitors of protein glycosylation

1980 • 104 citations

Early interaction between animal viruses and cells.

1974 • 103 citations

Penetration of Herpes Simplex Virus into Human Epidermoid Cells.

1964 • 100 citations

Inhibition of the Multiplication of Enveloped Viruses by Glucose Derivatives

1975 • 89 citations

Early Interactions of Viruses With Cellular Membranes

1979 • 89 citations

Infectious Herpesvirus DNA

1973 • 85 citations

Inhibition of Influenza Virus Multiplication with a Glucose Antimetabolite (2-deoxy-D-glucose)

1959 • 84 citations

Virus particle adsorption

1960 • 84 citations

Inhibition of Herpes Virus by Natural and Synthetic Acid Polysaccharides

1964 • 84 citations

Infectious DNA from Herpes Simplex Virus: Infectivity of Double-stranded and Single-stranded Molecules

1973 • 79 citations

Specific herpes simplex virus-induced incorporation of 5-iodo-5'-amino-2',5'-dideoxyuridine into deoxyribonucleic acid.

1976 • 74 citations

Effects of 2-deoxyglucose, glucosamine, and mannose on cell fusion and the glycoproteins of herpes simplex virus

1976 • 71 citations

Effect of 2-deoxy-D-glucose on cell fusion induced by Newcastle disease and Herpes simplex viruses

1973 • 70 citations

Interaction of Sindbis virus with liposomal model membranes

1975 • 70 citations

Successful Treatment of Human Genital Herpes Infections With 2-Deoxy-D-glucose

1979 • 69 citations

Inhibition of influenza viral glycoprotein synthesis by sugars.

1972 • 54 citations

Inhibition of Rous sarcoma virus replication by 2-deoxyglucose and tunicamycin: identification of an unglycosylated env gene product

1979 • 52 citations

Effect of Synthetic and Biological Polyanions on Herpes Simplex Virus.

1964 • 52 citations

Effect of 2‐Deoxy‐<scp>d</scp>‐glucose on the Cell‐Surface Glycoproteins of Hamster Fibroblasts

1977 • 48 citations

I. Introduction

2015 • 42 citations

A simple method for the purification of commercial neuraminidase preparations free from proteases

1973 • 39 citations

Isolation of herpes simplex virus DNA from the“Hirt supernatant”

1976 • 36 citations

Effects of cytochalasin B on herpes simplex virus type 1 replication

1976 • 35 citations

Herpes simplex virus protein synthesis in the presence of 2-deoxy-d-glucose

1976 • 32 citations

Synthesis of proteins in cells infected with herpesvirus

1972 • 28 citations

Transfection of human lymphoblastoid cells with herpes simplex viral DNA.

1979 • 20 citations

Lack of efficacy of 2-deoxy-D-glucose in the treatment of experimental herpes genitalis in guinea pigs

1982 • 19 citations

A NEW APPROACH TO VIRAL CHEMOTHERAPY

1974 • 16 citations

Membrane Glycoproteins of Enveloped Viruses

1978 • 15 citations

Herpes Simplex and Epstein-Barr Viruses in Human Cells and Tissues: A Study in Contrasts

1975 • 12 citations

Synthesis of proteins in cells infected with herpesvirus

1976 • 10 citations

The Inhibitory Effect of Compound 48/80 on the Formation of Giant Cells Induced by Herpesvirus Hominis

1971 • 10 citations

Anti-herpesvirus polychemotherapy.

1979 • 8 citations

Studies on the attachment of herpes simplex virus. Effect of trypsin treatment

1979 • 7 citations