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Selective alteration of DNA fragmentation and caspase activity in the spinal cord of aged rats and effect of dietary restriction

Data up to Jan 2025

Published2003
Citations13
References27

Total Citations Per Year

Abstract

References (27)

Biochemical Pathways of Caspase Activation During Apoptosis

1999 • 2,567 citations

Life and Death of Neurons in the Aging Brain

1997 • 1,323 citations

Gene-expression profile of the ageing brain in mice

2000 • 1,057 citations

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

2000 • 700 citations

A potential role for apoptosis in neurodegeneration and Alzheimer's disease

1995 • 382 citations

Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms

2003 • 290 citations

Activated caspase-3 expression in Alzheimer’s and aged control brain: correlation with Alzheimer pathology

2001 • 252 citations

Aging-associated Changes in Human Brain

1997 • 218 citations

Tissue transglutaminase: a possible role in neurodegenerative diseases

2000 • 170 citations

Caspases, Apoptosis, and Alzheimer Disease: Causation, Correlation, and Confusion

2001 • 169 citations

Molecular mechanisms of brain aging and neurodegenerative disorders: lessons from dietary restriction

2001 • 155 citations

Recent developments in the pathology of Parkinson’s disease

2002 • 155 citations

Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging.

1997 • 149 citations

Age-related changes in the protein expression of subunits of the NMDA receptor

2002 • 116 citations

The age‐related increase in IL‐1 type I receptor in rat hippocampus is coupled with an increase in caspase‐3 activation

2002 • 108 citations

Caspases on the brain

2002 • 106 citations

Qualitative and quantitative estimates of apoptosis from birth to senescence in the rat brain

2001 • 94 citations

Blockade of the NMDA receptor increases developmental apoptotic elimination of granule neurons and activates caspases in the rat cerebellum

2000 • 92 citations

Problems of cell death in neurodegeneration and Alzheimer's Disease

2001 • 91 citations

GABAergic Deafferentation Hypothesis of Brain Aging and Alzheimer’s Disease Revisited

1998 • 87 citations

Target-Derived Trophic Effect on Skeletal Muscle Innervation in Senescent Mice

2003 • 69 citations

Neurochemical changes in the aging human brain: implications for behavioral impairment and neurodegenerative disease.

1998 • 50 citations

N-methyl-d-aspartate receptor and L-type voltage-gated Ca2+ channel antagonists suppress the release of cytochrome c and the expression of procaspase-3 in rat hippocampus after global brain ischemia

2002 • 40 citations

Decline in motor functions in aging is related to the loss of NMDA receptors

2001 • 36 citations

Topography of neurochemical alterations in the CNS of aged rats

2001 • 15 citations

Increase of the ornithine decarboxylase/polyamine system and transglutaminase upregulation in the spinal cord of aged rats

2001 • 12 citations

Neuronal DNA damage correlates with overexpression of interleukin-1β converting enzyme in APPV717F mice

2001 • 12 citations

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Selective alteration of DNA fragmentation and caspase activity in the spinal cord of aged… (2003) – Brain Research | Metascience Observatory Explorer