High viral loads of human papillomavirus predict risk of invasive cervical carcinoma

NATURAL HISTORY OF CERVICOVAGINAL PAPILLOMAVIRUS INFECTION IN YOUNG WOMEN

1998 • 1,885 citations

A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.

1984 • 1,308 citations

Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm

1991 • 585 citations

Persistence and load of high‐risk HPV are predictors for development of high‐grade cervical lesions: A longitudinal French cohort study

2003 • 416 citations

Integrated Human Papillomavirus Type 16 Is Frequently Found in Cervical Cancer Precursors as Demonstrated by a Novel Quantitative Real-Time PCR Technique

2002 • 389 citations

Viral load of human papilloma virus 16 as a determinant for development of cervical carcinoma in situ: a nested case-control study

2000 • 371 citations

Human Papillomavirus Infection and Time to Progression and Regression of Cervical Intraepithelial Neoplasia

2003 • 331 citations

Distribution of 37 mucosotropic HPV types in women with cytologically normal cervical smears: The age-related patterns for high-risk and low-risk types

2000 • 276 citations

Effects of Age and Human Papilloma Viral Load on Colposcopy Triage: Data From the Randomized Atypical Squamous Cells of Undetermined Significance/Low-Grade Squamous Intraepithelial Lesion Triage Study (ALTS)

2002 • 271 citations

Human papillomavirus 16 load in normal and abnormal cervical scrapes: An indicator of CIN II/III and viral clearance

2002 • 262 citations

Viral load of human papillomavirus and risk of CIN3 or cervical cancer

2002 • 260 citations

Physical state and expression of HPV DNA in benign and dysplastic cervical tissue: different levels of viral integration are correlated with lesion grade

2004 • 196 citations

The link between integration and expression of human papillomavirus type 16 genomes and cellular changes in the evolution of cervical intraepithelial neoplastic lesions.

1997 • 145 citations

A prospective study showing long-term infection with human papillomavirus 16 before the development of cervical carcinoma in situ.

2000 • 136 citations

A comparison between real-time polymerase chain reaction and hybrid capture 2 for human papillomavirus DNA quantitation.

2003 • 134 citations

HPV16 and HPV18 in genital tumors: Significantly different levels of viral integration and correlation to tumor invasiveness

2002 • 133 citations

Real-Time PCR-Based System for Simultaneous Quantification of Human Papillomavirus Types Associated with High Risk of Cervical Cancer

2003 • 128 citations

Type‐specific associations of human papillomavirus load with risk of developing cervical carcinoma in situ

2004 • 121 citations

Determinants of human papillomavirus load among women with histological cervical intraepithelial neoplasia 3: dominant impact of surrounding low-grade lesions.

2003 • 119 citations

Viral load of high‐risk human papillomavirus in cervical squamous intraepithelial lesions

2002 • 111 citations

Analysis of HPV16, 18, 31, and 35 DNA in pre-invasive and invasive lesions of the uterine cervix.

1997 • 110 citations

Detection and Quantitation of Human Papillomavirus by Using the Fluorescent 5′ Exonuclease Assay

1999 • 84 citations