Cutaneous Chemical Carcinogenesis: Past, Present, And Future
Data up to Jan 2025
Total Citations Per Year
Abstract
References (87)
Arene Oxides: A New Aspect of Drug Metabolism
1974 • 1,043 citations
Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids).
1976 • 993 citations
The Function and Mechanism of Promoters of Carcinogenesis
1973 • 759 citations
Evidence for the Binding of Polynuclear Aromatic Hydrocarbons to the Nucleic Acids of Mouse Skin : Relation between Carcinogenic Power of Hydrocarbons and their Binding to Deoxyribonucleic Acid
1964 • 687 citations
Some Biological Aspects of Skin Carcinogenesis*
2015 • 640 citations
Polyamines in Normal and Neoplastic Growth
1976 • 545 citations
A New, Quantitative, Approach to the Study of the Stages of Chemical Carcinogenesis in the Mouse's Skin
1947 • 532 citations
Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents.
1975 • 504 citations
Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro
1974 • 437 citations
Carcinogenesis by Ultraviolet Light
1960 • 297 citations
106. The isolation of a cancer-producing hydrocarbon from coal tar. Parts I, II, and III
1933 • 297 citations
THE INITIATING AND PROMOTING ELEMENTS IN TUMOR PRODUCTION
1944 • 251 citations
Repair Replication, Unscheduled DNA Synthesis, and the Repair of Mammalian DNA
1969 • 242 citations
Inhibition of the carcinogenic action of benzo(a)pyrene by flavones.
1970 • 210 citations
Ultrastructural, histological, and biochemical alterations produced by 12-O-tetradecanoyl-phorbol-13-acetate on mouse epidermis and their relevance to skin tumor promotion.
1973 • 196 citations
The Persistence of Latent Tumour Cells Induced in the Mouse's Skin by a Single Application of 9:10-Dimethyl-1:2-Benzanthracene
1949 • 193 citations
The production of cancer by pure hydrocarbons. V
1940 • 191 citations
Studies on the mechanism of skin tumor promotion.
1970 • 187 citations
High-pressure liquid chromatographic analysis of benzo(alpha)pyrene metabolism and covalent binding and the mechanism of action of 7,8-benzoflavone and 1,2-epoxy-3,3,3-trichloropropane.
1974 • 175 citations
METABOLIC REGULATORY CIRCUITS AND CARCINOGENESIS.
1963 • 172 citations
Studies on the formation of protein-bound derivatives of 3,4-benzpyrene in the epidermal fraction of mouse skin.
1951 • 165 citations
Carcinogenesis as a biological problem
1976 • 163 citations
Effects of phorbol and four diesters of phorbol on the incorporation of tritiated precursors into DNA, RNA, and protein in mouse epidermis.
1971 • 159 citations
Medical Radiation Biology.
1973 • 156 citations
Tumor-promoting activity of phorbol and four diesters of phorbol in mouse skin.
1971 • 155 citations
Microsomal hydroxylases: induction and role in polycyclic hydrocarbon carcinogenesis and toxicity.
1972 • 119 citations
Binding of tritium-labeled polycyclic hydrocarbons to DNA of mouse skin.
1967 • 118 citations
The effect of aging and interval between primary and secondary treatment in two-stage carcinogenesis on mouse skin.
1975 • 116 citations
The stimulation of phospholipid metabolism in mouse skin following phorbol ester treatment
1972 • 113 citations
Aryl Hydrocarbon Hydroxylase and Polycyclic Hydrocarbon Tumorigenesis: Effect of the Enzyme Inhibitor 7,8-Benzoflavone on Tumorigenesis and Macromolecule Binding
1972 • 110 citations
Studies on the formation of hydrocarbon-deoxyribonucleoside products by the binding of derivatives of 7-methylbenz(a)anthracene to DNA in aqueous solution and in mouse embryo cells in culture.
1973 • 109 citations
Quantitative aspects of the reaction of some carcinogens with nucleic acids and the possible significance of such reactions in the process of carcinogenesis.
1966 • 106 citations
In vitro Transformation of Syrian Hamster Embryo Cells by Diverse Chemical Carcinogens
1972 • 103 citations
Growth and structural properties of epithelial cell cultures established from normal rat liver and chemically induced hepatomas.
1975 • 102 citations
A New Cyclization Reaction Leading to Epoxides of Aromatic Hydrocarbons
1964 • 97 citations
Stimulated DNA synthesis in mouse epidermal cell cultures treated with 12-O-tetradecanoyl-phorbol-13-acetate.
1976 • 94 citations
Induction of cell division: Role of cell membrane sites
1972 • 90 citations
The role of aryl hydrocarbon hydroxylase in 7,12-dimethylbenz(a)anthracene skin tumorigenesis: on the mechanism of 7,8-benzoflavone inhibition of tumorigenesis.
1972 • 87 citations
The tumor-enhancing principles of Croton tiglium L.
1965 • 86 citations
A modification of the technique of “skin splitting” with trypsin
1955 • 85 citations
Dose-response studies with a pure tumor-promoting agent, phorbol myristate acetate.
1973 • 79 citations
Stimulation of the phosphorylation of mouse epidermal histones by tumor-promoting agents.
1973 • 77 citations
The Growth of Fetal Mouse Skin in Cell Culture and Transplantation to F1 Mice**From the Experimental Pathology Branch, National Cancer InstituLe, Bethesda, Maryland 20014.
1970 • 75 citations
Cell proliferation and promoting action in skin carcinogenesis.
1974 • 73 citations
The correlation of promotion of tumour growth and of induction of hyperplasia in epidermal two-stage carcinogenesis
1968 • 72 citations
Acetic Acid, a Potent Stimulator of Mouse Epidermal Macromolecular Synthesis and Hyperplasia but With Weak Tumor-Promoting Ability 2
1975 • 72 citations
Phorbol ester tumor-promoting agents and membrane stability.
1969 • 70 citations
Aryl hydrocarbon (benzo [α] pyrene) hydroxylase: Inducible in extrahepatic tissues of mouse strains not inducible in liver
1973 • 67 citations
Formation of Epidermis After Reimplantation of Pure Primary Epidermal Cell Cultures From Perinatal Mouse Skin 2
1974 • 62 citations
Growth and Differentiation of Transplanted Epithelial Cell Cultures*
1968 • 62 citations
Deoxyribonucleoside incorporation during DNA repair of carcinogen-induced damage in human diploid fibroblasts.
1973 • 58 citations
THE PART PLAYED BY INJURY AND REPAIR IN THE DEVELOPMENT OF CANCER
1927 • 54 citations
A sensitising factor in experimental blastogenesis
1944 • 53 citations
Studies on promoting action in skin carcinogenesis
1963 • 49 citations
The effect of croton oil pretreatment on skin tumor initiation in mice.
1969 • 48 citations
Induction of melanotic lesions during skin carcinogenesis in hamsters.
1956 • 47 citations
The in vivo binding of beta-propiolactone to mouse skin DNA, RNA, and protein.
1968 • 46 citations
On the persistence of tumour initiation and the acceleration of tumour progression in mouse skin tumorigenesis
1972 • 46 citations
Aryl Hydrocarbon (Benzo[A]Pyrene) Hydroxylase: A Mixed-Function Oxygenase in Mouse Skin
1975 • 43 citations
"Spontaneous" neoplastic transformation of cells in vitro: some facts and theories.
1967 • 41 citations
A study of skin carcinogenesis in the mouse with single applications of 9,10-dimethyl-1,2-benzanthracene at different dosages.
1960 • 39 citations
Zur Kenntnis mehrkerniger aromatischer Kohlenwasserstoffe und ihrer Abkömmlinge, I. Mitt.: Dibenzanthracene und ihre Chinone
1929 • 39 citations
Chemical carcinogenesis in the Syrian golden hamster:A review
1969 • 37 citations
Studies on the cellular and molecular mechanisms of hydrocarbon carcinogenesis
1970 • 36 citations
Natural Synchrony Of Newborn Mouse Epidermal Cells In Vitro
1976 • 35 citations
Enhancement of skin tumorigenesis by a single application of croton oil before or soon after initiation by urethan.
1973 • 35 citations
Mechanism of Experimental Tumorigenesis. I. Epidermal Hyperplasia in Mouse Caused by Locally Applied Tumor Initiator and Dipole-Type Tumor Promotor<xref ref-type="fn" rid="FN1">2</xref>
1959 • 34 citations
98. The synthesis of 5 : 6-dimethyl-1 : 2-benzanthraquinone, a degradation product of deoxycholic acid
1934 • 33 citations
Medical Radiation Biology
1957 • 33 citations
The production of cancer by pure hydrocarbons. VI
1942 • 32 citations
RNA synthesis induction in cell culture by a tumor promoter.
1970 • 31 citations
The binding of 7,12-dimethylbenz(a)anthracene to replicating and non-replicating DNA in cell culture
1969 • 26 citations
Anticarcinogenesis�an Alternative
2015 • 26 citations
Dimethyl sulfoxide-induced enhancement of 7,12-dimethylbenz(a)anthracene metabolism and DNA binding in differentiating mouse epidermal cell cultures.
1976 • 24 citations
In Vitro Neoplastic Transformation of Mouse Skin Cells: Morphology and Ultrastructure of Cells and Tumors
1974 • 21 citations
Interactions of phorbol esters with cellular membranes in vitro.
1973 • 20 citations
Carcinogenesis By Ultraviolet Light
1960 • 18 citations
Effects of carcinogenic, noncarcinogenic, and cocarcinogenic agents on the biosynthesis of nucleic acids in mouse skin.
1969 • 18 citations
In vitro binding of labeled 20-methylcholanthrene to a specific cytosol-protein
1973 • 17 citations
Guanine-specific DNA repair after treatment of mouse skin cells with N-methyl-N'-nitro-N-nitrosoguanidine.
1976 • 16 citations
Replication of DNA After Binding of the Carcinogen 7,12-Dimethylbenz [<italic>a</italic>] anthracene
1970 • 15 citations
In Vitro Cultivation of a Chemically Induced Epidermal Carcinoma: Establishment of Three Cell Lines and Isolation of Murine Leukemia Virus
1973 • 12 citations
Purine-Specific Repair of β-Propiolactone-Induced Dna Damage in Mouse Skin Cells
1974 • 11 citations
Factors Influencing the Incidence of Epidermal Methylcholanthrene Tumors in Mice Treated with Cortisone
1955 • 11 citations
MELANOMAS OF THE SKIN OF GUINEA PIGS FOLLOWING THE APPLICATION OF A SOLUTION OF 9,10-DIMETHYL-1,2-BENZANTHRACENE IN BENZENE.
1963 • 10 citations
Factors Influencing the Incidence of Epidermal Methylcholanthrene Tumors in Mice Treated with Cortisone
1955 • 9 citations
Features of tumor enhancement by croton oil.
1968 • 8 citations