Air pollutants, oxidative stress and human health

Lung Cancer, Cardiopulmonary Mortality, and Long-term Exposure to Fine Particulate Air Pollution

2002 • 8,253 citations

Air pollution and health

2002 • 4,454 citations

Casarett and Doull's Toxicology: The Basic Science of Poisons

1992 • 3,276 citations

Particulate Air Pollution as a Predictor of Mortality in a Prospective Study of U.S. Adults

1995 • 2,712 citations

Fine Particulate Air Pollution and Hospital Admission for Cardiovascular and Respiratory Diseases

2006 • 2,524 citations

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1985 • 2,154 citations

Association between mortality and indicators of traffic-related air pollution in the Netherlands: a cohort study

2002 • 1,577 citations

Pulmonary effects of inhaled ultrafine particles

2000 • 1,290 citations

Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults.

1995 • 1,159 citations

Epidemiology of fine particulate air pollution and human health: biologic mechanisms and who's at risk?

2000 • 907 citations

Oxidative Stress as a Regulator of Gene Expression in the Vasculature

1999 • 810 citations

Acute Effects of Particulate Air Pollution on Respiratory Admissions

2001 • 667 citations

Particulate Air Pollution and Hospital Emergency Room Visits for Asthma in Seattle

1993 • 656 citations

Daily Mortality and PM₁₀ Pollution in Utah Valley

1992 • 624 citations

Casarett and Doull's Toxicology: The Basic Science of Poisons

1981 • 622 citations

Long-Term Effects of Traffic-Related Air Pollution on Mortality in a Dutch Cohort (NLCS-AIR Study)

2007 • 590 citations

Air Pollution and Hospital Admissions for Cardiovascular Disease in Detroit, Michigan

1995 • 519 citations

Association of Low-Level Ozone and Fine Particles With Respiratory Symptoms in Children With Asthma

2003 • 480 citations

Role of transcription factors in inflammatory lung diseases

1998 • 455 citations

MORTALITY AND AIR POLLUTION J LONDON: A TIME SERIES ANALYSIS

1990 • 446 citations

Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema

1997 • 439 citations

Respiratory Hospital Admissions Associated with PM₁₀Pollution in Utah, Salt Lake, and Cache Valleys

1991 • 420 citations

Particulate Air Pollution and Daily Mortality in Steubenville, Ohio

1992 • 416 citations

Epidemiologic evidence of cardiovascular effects of particulate air pollution.

2001 • 414 citations

Epidemiology of Fine Particulate Air Pollution and Human Health: Biologic Mechanisms and Who's at Risk?

2000 • 392 citations

How Exposure to Environmental Tobacco Smoke, Outdoor Air Pollutants, and Increased Pollen Burdens Influences the Incidence of Asthma

2006 • 365 citations

Cecil Textbook of Medicine

1992 • 336 citations

Mitochondrial oxidative stress after carbon monoxide hypoxia in the rat brain.

1992 • 325 citations

Metabolic Polymorphisms and Susceptibility to Cancer

1999 • 318 citations

Cardiovascular diseases and the work environment. A critical review of the epidemiologic literature on chemical factors.

1989 • 306 citations

Effects of air pollutants on acute stroke mortality.

2002 • 299 citations

Air Pollution

2002 • 286 citations

The role of particulate size and chemistry in the association between summertime ambient air pollution and hospitalization for cardiorespiratory diseases.

1997 • 274 citations

Metabolic modulation of carbon monoxide toxicity

2002 • 271 citations

Effect of diet on cancer development: is oxidative DNA damage a biomarker?1,2 1This article is part of a series of reviews on “Oxidative DNA Damage and Repair.” The full list of papers may be found on the homepage of the journal. 2Guest Editor: Miral Dizdaroglu

2002 • 263 citations

Associations of daily mortality and air pollution in Los Angeles County

1991 • 257 citations

Molecular pathogenesis of emphysema

2008 • 248 citations

Linking exposure to environmental pollutants with biological effects

2003 • 233 citations

The effect of air pollution on inner-city children with asthma

2002 • 231 citations

Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease?

2001 • 219 citations

Short term fluctuations in air pollution and hospital admissions of the elderly for respiratory disease.

1995 • 219 citations

The Big Smoke: A History of Air Pollution in London since Medieval Times

1989 • 215 citations

Ambient air pollution and hospitalization for congestive heart failure among elderly people in seven large US cities.

1995 • 214 citations

The Effect of Dose and Timing of Dose on the Association between Airborne Particles and Survival

2007 • 214 citations

Ozone Concentration and Pulmonary Response Relationships for 6.6-Hour Exposures with Five Hours of Moderate Exercise to 0.08, 0.10, and 0.12 ppm

1990 • 213 citations

Air Pollution and Emergency Room Admissions for Chronic Obstructive Pulmonary Disease: A 5-year Study

1993 • 212 citations

Association between Ambient Carbon Monoxide Levels and Hospitalizations for Congestive Heart Failure in the Elderly in 10 Canadian Cities

1997 • 199 citations

Inhaled particles, III

1972 • 196 citations

Air Pollution and Hospital Admissions for Cardiovascular Disease in Tucson

1997 • 187 citations

The relationship of daily mortality to suspended particulates in Santa Clara County, 1980-1986.

1990 • 187 citations

Air pollution and hospital admissions in Sydney, Australia, 1990 to 1994.

1998 • 177 citations

Association between lung cancer and microsomal epoxide hydrolase genotypes.

1998 • 176 citations

Association of Tumor Necrosis Factor α Gene Promoter Polymorphism with the Presence of Chronic Obstructive Pulmonary Disease

2001 • 170 citations

Air pollution and acute respiratory illness in five german communities

1991 • 169 citations

Effects of Urban Air Pollution on Emergency Room Admissions for Chronic Obstructive Pulmonary Disease

1991 • 157 citations

Air Pollution and Lung Cancer in Trieste, Italy

1995 • 147 citations

Effects of acute controlled exposure to SO₂ on respiratory mechanics in healthy male adults

1962 • 143 citations

Epidemiologic Evidence of Cardiovascular Effects of Particulate Air Pollution

2001 • 141 citations

GSTM1 and GSTP1 and respiratory health in asthmatic children exposed to ozone

2006 • 141 citations

Genetics and pulmonary medicine bullet 9: Molecular genetics of chronic obstructive pulmonary disease

1999 • 139 citations

7 Genotyping for human whole-genome scans: Past, present, and future

2001 • 136 citations

HEART DISEASE MORTALITY AMONG BRIDGE AND TUNNEL OFFICERS EXPOSED TO CARBON MONOXIDE1

1988 • 131 citations

Pathogenesis of Chronic Obstructive Pulmonary Disease

2007 • 131 citations

Cecil Textbook of Medicine : 19th edition

1992 • 127 citations

Tyrosine Nitration of c-SRC Tyrosine Kinase in Human Pancreatic Ductal Adenocarcinoma

2000 • 118 citations

A new direction in the pathogenesis of idiopathic pulmonary fibrosis?

2001 • 116 citations

The Effects of Ozone and Nitrogen Dioxide on Pulmonary Function in Healthy and in Asthmatic Adolescents

1987 • 110 citations

The role of reactive oxygen species and oxidative stress in mediating particulate matter injury.

2006 • 109 citations

The big smoke, a history of air pollution in London since medieval times

1988 • 103 citations

Peroxynitrite Induces Covalent Dimerization of Epidermal Growth Factor Receptors in A431 Epidermoid Carcinoma Cells

1998 • 100 citations

Experimental Study of Hypersecretion of Mucus in the Bronchial Tree

1963 • 100 citations

N-acetyltranferase NAT1 and NAT2 genotypes and lung cancer risk

1998 • 98 citations

Oxidative and nitrosative stress markers in bus drivers

2007 • 95 citations

Effects of Ambient Ozone on Respiratory Function in Healthy Adults Exercising Outdoors

1988 • 92 citations

Ozone-induced production of nitric oxide and TNF-α and tissue injury are dependent on NF-κB p50

2004 • 92 citations

Gene-Air Pollution Interactions in Asthma

2007 • 90 citations

Effect of short-term exposure to low levels of gaseous pollutants on chronic obstructive pulmonary disease hospitalizations

2004 • 89 citations

Acute elevation of blood carboxyhemoglobin to 6% impairs exercise performance and aggravates symptoms in patients with ischemic heart disease

1988 • 86 citations

Relation of Daily Mortality to Air Pollution: An Analysis of 14 London Winters, 1958/59–1971/72

1982 • 85 citations

A search for a threshold in the relationship of air pollution to mortality: a reanalysis of data on London winters.

1984 • 82 citations

The Relation of Air Pollution to Mortality

1976 • 74 citations

CARDIOVASCULAR DISEASE HOSPITALIZATION AND AMBIENT LEVELS OF CARBON MONOXIDE

1998 • 71 citations

Fate and distribution of inhaled nitrogen dioxide in rhesus monkeys.

1977 • 69 citations

Chronic Bronchitis, Emphysema, and Low-Level Air Pollution in Helsinki, 1987-1989

1994 • 66 citations

Release of glutathione from erythrocytes and other markers of oxidative stress in carbon monoxide poisoning

1997 • 64 citations

Nitric oxide release from S-nitrosoglutathione (GSNO)

1999 • 62 citations

Toxicological mechanisms underlying oxidant pollutant-induced airway injury.

1998 • 61 citations

Particulate Air Pollution and Asthma: A Review of Epidemiological and Biological Studies

1999 • 58 citations

Factors affecting the response of lung clearance systems to acid aerosols: role of exposure concentration, exposure time, and relative acidity.

1989 • 58 citations

Seasonal variability of oxidative stress markers in city bus drivers

2008 • 57 citations

Asthma, Genes, and Air Pollution

2005 • 57 citations

Ambient particulate matter causes activation of the c-jun kinase/stress-activated protein kinase cascade and DNA synthesis in lung epithelial cells.

1998 • 56 citations

Metabolic genetic polymorphisms and susceptibility to lung cancer

2001 • 56 citations

Effects of Inhalation of 0.25 ppm Ozone on the Terminal Bronchioles of Juvenile and Adult Rats

1988 • 51 citations

Genomics and proteomics: importance for the future of nutrition research

2002 • 49 citations

Pollution and allergic airways disease

2001 • 48 citations

Lack of Effect of Low Levels of Carboxyhemoglobin on Cardiovascular Function in Patients with Ischemic Heart Disease

1987 • 47 citations

Reactive uptake governs the pulmonary air space removal of inhaled nitrogen dioxide

1990 • 46 citations

Pollution and allergic airways disease

2001 • 45 citations

Genomics and proteomics: importance for the future of nutrition research

2002 • 41 citations

The British museum book of ancient Egypt

1993 • 39 citations

Pulmonary disposition of inhaled NO2-nitrogen in isolated rat lungs

1989 • 37 citations

The Effect of Air Pollution upon Mortality: A Consideration of Distributed Lag Models

1978 • 35 citations

Fate of inhaled nitrogen dioxide in isolated perfused rat lung

1981 • 35 citations

Effect of air pollution on lung cancer: a Poisson regression model based on vital statistics.

1994 • 32 citations

Effects of Air Pollution

1996 • 31 citations

AIR PARTICULATE POLLUTION AND HOSPITAL ADMISSIONS FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN RENO, NEVADA

2000 • 30 citations

Estimation of the Natural Background of Ozone Present at Surface Rural Locations

1987 • 25 citations

Early alveolar clearance of particles in rabbits undergoing acute and subchronic exposure to ozone

1986 • 25 citations

Pollution atmosphérique et maladies respiratoires allergiques

2007 • 24 citations

Genetic polymorphisms in lung disease: bandwagon or breakthrough?

2002 • 23 citations

Update on the health effects of outdoor air pollution

2002 • 22 citations

Familial Aggregation of Severe, Early-Onset COPD

2000 • 22 citations

Maximal aerobic capacity at several ambient concentrations of CO at several altitudes

1988 • 21 citations

Inhalation toxicology. Research methods, applications and evaluation

1988 • 21 citations

Epidemiologic studies on the health effects of ambient particulate air pollution.

2000 • 21 citations

Longman Dictionary of Environmental Science

1998 • 21 citations

The British Museum book of ancient Egypt

1999 • 20 citations

Fumifugium, or, The inconveniencie of the aer and smoak of London dissipated : together with some remedies humbly proposed by J.E. Esq., to His Sacred Majestie, and to the Parliament now assembled

1977 • 18 citations

Effects on Canine Pulmonary Function

1969 • 16 citations

Post-genomic opportunities for understanding nutrition: the nutritionist's perspective

2002 • 14 citations

Carbon monoxide levels in cardiac patients in an urban emergency department

1986 • 13 citations

A MATCHED PAIRS COMPARISON OF CYCLE ERGOMETRY AND TREADMILL EXERCISE TESTING IN THE EVALUATION OF CORONARY HEART DISEASE

1987 • 11 citations

Acute Effects of Air Pollutants on the Lungs

1968 • 11 citations

The Effect of Air Pollution Upon Mortality: A Consideration of Distributed Lag Models

1978 • 9 citations

A COMPARISON OF TWO STATISTICAL MODELS FOR ANALYZING THE ASSOCIATION BETWEEN PM<SUB>10</SUB> AND HOSPITAL ADMISSIONS FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE

2001 • 1 citations