Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1985 • 29,733 citations

Global and societal implications of the diabetes epidemic

2001 • 5,825 citations

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

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A DATA-BASED APPROACH TO DIET QUESTIONNAIRE DESIGN AND TESTING

1986 • 2,156 citations

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

2008 • 1,814 citations

Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and β‐cell dysfunction

2002 • 1,264 citations

Insulin sensitivity: modulation by nutrients and inflammation

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Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

2008 • 1,126 citations

Disordered Lipid Metabolism and the Pathogenesis of Insulin Resistance

2007 • 1,040 citations

Reversal of Nonalcoholic Hepatic Steatosis, Hepatic Insulin Resistance, and Hyperglycemia by Moderate Weight Reduction in Patients With Type 2 Diabetes

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Ceramides in insulin resistance and lipotoxicity

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Plasma Amino Acid Levels and Insulin Secretion in Obesity

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Accelerated Loss of Skeletal Muscle Strength in Older Adults With Type 2 Diabetes

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Relationship between obesity, insulin resistance, and coronary heart disease risk

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Sarcopenic obesity and inflammation in the InCHIANTI study

2006 • 547 citations

Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism

2007 • 464 citations

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

2004 • 448 citations

Relationships Between Circulating Metabolic Intermediates and Insulin Action in Overweight to Obese, Inactive Men and Women

2009 • 399 citations

Prediction of hypertension, diabetes, dyslipidaemia or albuminuria using simple anthropometric indexes in Hong Kong Chinese

1999 • 381 citations

Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in insulin-dependent diabetes.

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Sarcopenic Obesity: Does Muscle Loss Cause Fat Gain?: Lessons from Rheumatoid Arthritis and Osteoarthritis^a

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Relationship of Fat Distribution to Glucose Tolerance: Results of Computed Tomography in Male Participants of the Normative Aging Study

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Insulin resistance: a contributing factor to age-related muscle mass loss?

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Physical Inactivity and Obesity Underlie the Insulin Resistance of Aging

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Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling

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Prevalence of diabetes and ethnic differences in cardiovascular risk factors. The 1992 Singapore National Health Survey.

1999 • 208 citations

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Plasma Amino Acid Levels and Insulin Secretion in Obesity

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Cardiovascular diseases in Chinese, Malays, and Indians in Singapore. II. Differences in risk factor levels.

1990 • 184 citations

Insulin Resistance of Protein Metabolism in Type 2 Diabetes

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Adjuvant arthritis as a model of inflammatory cachexia

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High heritability of metabolomic profiles in families burdened with premature cardiovascular disease

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Levels of cardiovascular disease risk factors in Singapore following a national intervention programme.

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Impaired plasma fatty acid oxidation in extremely obese women

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Insulin Resistance and Muscle Strength in Older Persons

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Whole-body protein anabolic response is resistant to the action of insulin in obese women

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Whole-body protein anabolic response is resistant to the action of insulin in obese women

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ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease

2004 • 101 citations

Determinants of Whole-Body Protein Metabolism in Subjects With and Without Type 2 Diabetes

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Should Central Obesity Be an Optional or Essential Component of the Metabolic Syndrome?

2007 • 74 citations

Ethnicity modifies the association between diabetes mellitus and ischaemic heart disease in Chinese, Malays and Asian Indians living in Singapore

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Regional muscle and adipose tissue amino acid metabolism in lean and obese women

2002 • 66 citations

Is There a Clear Threshold for Fasting Plasma Glucose That Differentiates Between Those With and Without Neuropathy and Chronic Kidney Disease?: The Singapore Prospective Study Program

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Muscle Strength is a Marker of Insulin Resistance in Patients with Type 2 Diabetes: A Pilot Study

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Whole-body skeletal muscle mass is not related to glucose tolerance or insulin sensitivity in overweight and obese men and women

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Validation of a semiquantitative food frequency questionnaire for estimation of intakes of energy, fats and cholesterol among Singaporeans

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Homeostasis model assessment in a population with mixed ethnicity: the 1992 Singapore National Health Survey

2000 • 48 citations

Weight Reduction and the Impaired Plasma-Derived Free Fatty Acid Oxidation in Type 2 Diabetic Subjects¹

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Can dietary factors explain differences in serum cholesterol profiles among different ethnic groups (Chinese, Malays and Indians) in Singapore?

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Diabetes mellitus and its chronic complications in Singapore: an increasing healthcare problem.

1990 • 20 citations

Diabetes Mellitus, Lipidus Et... Proteinus!

2002 • 10 citations