Xeroderma pigmentosum variant cells are less likely than normal cells to incorporate dAMP opposite photoproducts during replication of UV-irradiated plasmids.

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

MUTAGENESIS BY APURINIC/APYRIMIDINIC SITES

1986 • 884 citations

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats

1985 • 829 citations

Xeroderma Pigmentosum

1974 • 755 citations

Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation.

1975 • 617 citations

Effect of physiologic hyperinsulinemia on skeletal muscle protein synthesis and breakdown in man.

1987 • 519 citations

Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts

1988 • 448 citations

Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cells

1976 • 331 citations

A shuttle vector plasmid for studying carcinogen-induced point mutations in mammalian cells

1985 • 259 citations

Xeroderma Pigmentosum: Variants with Normal Dna Repair and Normal Sensitivity to Ultraviolet Light

1972 • 244 citations

Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells.

1986 • 215 citations

Sequence specificity of point mutations induced during passage of a UV-irradiated shuttle vector plasmid in monkey cells.

1986 • 167 citations

Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.

1987 • 132 citations

Repair of UV-endonuclease-susceptible sites in the 7 complementation groups of xeroderma pigmentosum a through G

1979 • 132 citations

Mechanisms of inhibition of DNA replication by ultraviolet light in normal human and xeroderma pigmentosum fibroblasts

1981 • 121 citations

Spontaneous activation of a human proto-oncogene.

1983 • 114 citations

Postreplication repair: questions of its definition and possible alteration in xeroderma pigmentosum cell strains.

1979 • 101 citations

Kinds of mutations formed when a shuttle vector containing adducts of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene replicates in human cells.

1987 • 98 citations

Rapid repair kinetics of pyrimidine(6–4)pyrimidone photoproducts in human cells are due to excision rather than conformational change

1990 • 92 citations

Identification of the altered bases in mutated single-stranded DNA

1964 • 84 citations

Extent of excision repair before DNA synthesis determines the mutagenic but not the lethal effect of UV radiation

1982 • 82 citations

Ultraviolet mutagenesis of normal and xeroderma pigmentosum variant human fibroblasts

1979 • 76 citations

Error-prone mutagenesis detected in mammalian cells by a shuttle vector containing the supF gene of Escherichia coli.

1984 • 75 citations

Xeroderma pigmentosum variants have a slow recovery of DNA synthesis after irradiation with ultraviolet light

1979 • 73 citations

Defective postreplication repair in xeroderma pigmentosum variant fibroblasts.

1990 • 70 citations

In vitro bypass of UV-induced lesions by Escherichia coli DNA polymerase I: specificity of nucleotide incorporation.

1983 • 67 citations

XERODERMA PIGMENTOSUM FIBROBLASTS INCLUDING CELLS FROM XP VARIANTS ARE ABNORMALLY SENSITIVE TO THE MUTAGENIC AND CYTOTOXIC ACTION OF BROAD SPECTRUM SIMULATED SUNLIGHT

1984 • 51 citations

Excision repair of UV- or benzo[a]pyrene diol epoxide-induced lesions in xeroderma pigmentosum variant cells is ‘error free’

1985 • 50 citations

DNA excision repair in cell extracts from human cell lines exhibiting hypersensitivity to DNA-damaging agents.

1991 • 39 citations

Modification of MCDB 110 medium to support prolonged growth and consistent high cloning efficiency of diploid human fibroblasts

1987 • 38 citations

Ultraviolet-induced dimerization of non-adjacent pyrimidines

1988 • 35 citations

The development of transient SV40 based shuttle vectors for mutagenesis studies: Problems and solutions

1989 • 34 citations

Error-Prone Mutagenesis Detected in Mammalian Cells by a Shuttle Vector Containing the supF Gene of Escherichia coli

1984 • 20 citations

Xeroderma Pigmentosum Variant Cells Are Not Defective in the Repair of (6–4) Photoproducts

1987 • 19 citations

Detection and repair of a UV-induced photosensitive lesion in the DNA of human cells

1986 • 13 citations