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Behavioral effects of a novel kappa opioid analgesic, U-50488, in rats and rhesus monkeys

Data up to Jan 2025

Published1985
Citations81
References21

Total Citations Per Year

Abstract

References (21)

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

U-50,488: a selective and structurally novel non-Mu (kappa) opioid agonist.

1983 • 795 citations

Experimental Morphine Addiction: Method for Automatic Intravenous Injections in Unrestrained Rats

1962 • 638 citations

Bremazocine: A potent, long-acting opiate kappa-agonist

1980 • 314 citations

Prediction of abuse liability of drugs using IV self-administration by rats

1983 • 234 citations

Long-term intravenous infusion

1972 • 234 citations

A kappa opioid effect: increased urination in the rat.

1983 • 224 citations

An opioid benzodiazepine

1982 • 201 citations

Properties of a selective kappa agonist, U-50,488H

1982 • 195 citations

Long-term Intravenous Infusion

1972 • 169 citations

Relative involvement of mu, kappa and delta receptor mechanisms in opiate-mediated antinociception in mice.

1983 • 153 citations

U-50,488, a selective kappa opioid agonist: Comparison to other reputed kappa agonists

1982 • 102 citations

Multiple opiate receptors: [3H]ethylketocyclazocine receptor binding and ketocyclazocine analgesia.

1980 • 91 citations

Induction of physical dependence on morphine, codeine and meperidine in the rat by continuous infusion.

1974 • 85 citations

Pharmacological analysis of the discriminative stimulus characteristics of ethylketazocine in the rhesus monkey.

1981 • 70 citations

Multiplicity of opiate receptors in different species

1982 • 53 citations

Dose and physical dependence as factors in the self-administration of morphine by rats

1979 • 35 citations

Discriminative effects of ethylketazocine in the rat: Stereospecificity and antagonism by naloxone

1982 • 32 citations

Discriminative stimulus properties of stereoisomers of cyclazocine in phencyclidine-trained squirrel monkeys

1982 • 25 citations

Discriminative stimulus properties of nalorphine in the rhesus monkeys.

1983 • 24 citations

Annual report: dependence studies of new compounds in the rhesus monkey (1980).

1981 • 11 citations

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