Effects of glucose, insulin or aldose reductase inhibition on responses to endothelin‐1 of aortic rings from streptozotocin‐induced diabetic rats

Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.

1977 • 2,105 citations

Drugs producing diabetes through damage of the insulin secreting cells.

1970 • 733 citations

Enhanced secretion of endothelin‐1 by elevated glucose levels from cultured bovine aortic endothelial cells

1990 • 196 citations

Effect of glucose and insulin on immunoreactive endothelin-1 release from cultured porcine aortic endothelial cells

1991 • 116 citations

A Contrasting effect of the diabetic state upon the contractile responses of aortic preparations from the rat and rabbit

1987 • 115 citations

Attenuated responses to endothelin‐1, KCl and CaCl₂, but not noradrenaline, of aortae from rats with streptozotocin‐induced diabetes mellitus

1991 • 82 citations

Endothelium-derived vasoactive substances: potential role in hypertension, atherosclerosis, and vascular occlusion.

1989 • 66 citations

Glucose-induced microvascular functional changes in nondiabetic rats are stereospecific and are prevented by an aldose reductase inhibitor.

1990 • 63 citations

Endothelium-Derived Vasoactive Substances

1989 • 55 citations

Activation of human erythrocyte, brain, aorta, muscle, and ocular tissue aldose reductase

1986 • 46 citations

The effect of elevated glucose levels on myo-inositol metabolism in cultured bovine aortic endothelial cells

1989 • 40 citations

Comparative pharmacology of rat and porcine endothelin in rat aorta and pulmonary artery

1989 • 39 citations

Prevention of peripheral nerve dysfunction by an aldose reductase inhibitor in streptozotocin-diabetic rats

1984 • 37 citations

Introduction: Evidence for the role of the polyol pathway in the pathophysiology of diabetic complications

1986 • 30 citations

Streptozotocin‐induced diabetes reduces the density of [¹²⁵I]‐endothelin‐binding sites in rat cardiac membranes

1989 • 29 citations

Modulation by endothelium of the responses induced by endothelin‐1 and by some of its analogues in rat isolated aorta

1991 • 25 citations

Chapter 17. Chronic Complications of Diabetes

1978 • 13 citations

Effects of an aldose reductase inhibitor, ONO-2235, insulin and their combination on the altered responsiveness to the nerve stimulation and agonists of the isolated atria of diabetic rats.

1990 • 12 citations