Endothelium‐dependent increase in vascular sensitivity to phenylephrine in long‐term streptozotocin diabetic rat aorta

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

1989 • 2,183 citations

Regulatory Functions of the Vascular Endothelium

1990 • 1,899 citations

Drugs which inhibit prostaglandin biosynthesis.

1974 • 1,325 citations

The Role of Endothelium in the Responses of Vascular Smooth Muscle to Drugs

1984 • 937 citations

Endothelium-dependent relaxation of coronary arteries by noradrenaline and serotonin

1983 • 855 citations

Drugs producing diabetes through damage of the insulin secreting cells.

1970 • 733 citations

Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

1978 • 715 citations

The nature of endothelium-derived vascular relaxant factor

1984 • 591 citations

Log-normal distribution of equiefective doses of norepinephrine and acetylcholine in several tissues.

1972 • 430 citations

Depression of contractile responses in rat aorta by spontaneously released endothelium-derived relaxing factor.

1986 • 381 citations

Attenuation of endothelium-dependent relaxation in aorta from diabetic rats

1986 • 350 citations

Mediators produced by the endothelial cell.

1988 • 329 citations

Impairment of endothelium‐dependent relaxation in aortae from spontaneously diabetic rats

1988 • 255 citations

Enhanced responsiveness of rat isolated aorta to clonidine after removal of the endothelial cells

1984 • 225 citations

Diabetes and hypertensive vascular disease

1973 • 208 citations

Decreased vascular prostacyclin in experimental diabetes

1978 • 203 citations

The dopamine autoreceptor agonist B-HT 920 stimulates denervated postsynaptic brain dopamine receptors in rodent and primate models of Parkinson's disease: a novel approach to treatment

1986 • 183 citations

Inhibition of rat mesangial cell mitogenesis by nitric oxide-generating vasodilators

1989 • 166 citations

Enhancement of alpha-1 and alpha-2 adrenergic agonist-induced vasoconstriction by removal of endothelium in rat aorta.

1985 • 163 citations

Endothelium-Dependent Relaxation in Aorta of BB Rat

1987 • 151 citations

Vascular reactivity in diabetes mellitus: role of the endothelial cell

1983 • 134 citations

A Contrasting effect of the diabetic state upon the contractile responses of aortic preparations from the rat and rabbit

1987 • 115 citations

Influence of the endothelium on contractile responses of arteries from diabetic rats

1988 • 106 citations

The influence of chronic experimental diabetes on contractile responses of rat isolated blood vessels

1985 • 100 citations

Modulation of vascular tonus by the endothelium in experimental diabetes

1987 • 88 citations

Vascular Disease in Diabetes

1979 • 79 citations

Endothelium-dependent relaxation in aorta of BB rat

1987 • 76 citations

Endothelial mediated inhibition of contraction and increase in cyclic GMP levels evoked by the α‐adrenoceptor agonist B‐HT 920 in rat isolated aorta

1984 • 73 citations

Insulin reversal of diabetes-induced inhibition of vascular contractility in the rat

1982 • 68 citations

Enhanced vascular alpha-adrenergic neuroeffector system in diabetes: importance of calcium

1988 • 68 citations

Vascular responses to agonists in rat mesenteric artery from diabetic rats

1987 • 66 citations

Nifedipine and alpha adrenoceptors in rat aorta. II. Role of extracellular calcium in enhanced alpha-2 adrenoceptor-mediated contraction in diabetes.

1984 • 59 citations

The modulatory role of vascular endothelium in the interaction of agonists and antagonists with α‐adrenoceptors in the rat aorta

1988 • 55 citations

Vascular responsiveness and eicosanoid production in diabetic rats

1983 • 51 citations

Aortic endothelium of alloxan diabetic rabbits: A quantitative study using scanning electron microscopy

1982 • 39 citations

Injury of arterial endothelial cells in diabetic, sucrose-fed and aged rats

1984 • 39 citations

SUPERSENSITIVITY OF ISOLATED MESENTERIC ARTERIES TO NORADRENALINE IN THE LONG‐TERM EXPERIMENTAL DIABETIC RAT

1981 • 35 citations

Impact of Insulin or Tolbutamide Treatment on 14C-Arachidonic Acid Conversion to Prostacyclin and/or Thromboxane in Lungs, Aortas, and Platelets of Streptozotocin-induced Diabetic Rats

1983 • 33 citations

Role of efficacy in the assessment of the actions of α-adrenoceptor agonists in rat aorta with endothelium

1986 • 33 citations

Differences in vascular responses to vasoactive agents of basilar artery and aorta from rabbits with alloxan-induced diabetes

1990 • 33 citations

Augmented thromboxane generation by mesenteric arteries from pancreatectomized diabetic dogs is coincident with the vascular tone enhancement evoked by Na arachidonate and prostacyclin

1984 • 26 citations

Impact of insulin or tolbutamide treatment on 14C-arachidonic acid conversion to prostacyclin and/or thromboxane in lungs, aortas, and platelets of streptozotocin-induced diabetic rats

1983 • 21 citations

Altered Responsiveness of Diabetic Dog Renal Arteries to Acetylcholine and Phenylephrine: Role of Endothelium

1989 • 15 citations

Differential contractile responsiveness of femoral arteries from healthy and diabetic dogs: role of endothelium.

1987 • 13 citations

Pharmacological studies on the responsiveness of cardiovascular tissues from diabetic rats

1991 • 1 citations

Heart rate and blood pressure response to methacholine in long term streptozotocin diabetic rats.

1988 • 1 citations