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Molecular mechanisms of drug resistance in fungi

Data up to Jan 2025

Published1994
Citations254
References40

Total Citations Per Year

Abstract

References (40)

A Controlled Trial of Fluconazole to Prevent Fungal Infections in Patients Undergoing Bone Marrow Transplantation

1992 • 1,179 citations

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Amphotericin B-resistant yeast infection in severely immunocompromised patients

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Resistance of yeasts to azole-derivative antifungals

1993 • 228 citations

Characterization of an azole-resistant Candida glabrata isolate

1992 • 207 citations

Variations in fluconazole susceptibility and electrophoretic karyotype among oral isolates of Candida albicans from patients with AIDS and oral candidiasis

1994 • 205 citations

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1984 • 189 citations

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1984 • 169 citations

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1983 • 156 citations

Correlation of in vitro fluconazole resistance of Candida isolates in relation to therapy and symptoms of individuals seropositive for human immunodeficiency virus type 1

1993 • 155 citations

Aspergillus and Aspergillosis

1988 • 135 citations

Sterol biosynthesis inhibitors. Pharmaceutical and agrochemical aspects.

1988 • 135 citations

Fatal septicemia due to amphotericin B-resistant Candida lusitaniae

1983 • 131 citations

Candida albicans genotyping in studies with patients with AIDS developing resistance to fluconazole

1993 • 119 citations

Resistance of Candida albicans to azole antifungal agents

1993 • 119 citations

Mutation in cytochrome P-450-dependent 14α-demethylase results in decreased affinity for azole antifungals

1990 • 118 citations

The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization

1991 • 117 citations

Randomized comparison of oral fluconazole versus oral polyenes for the prevention of fungal infection in patients at risk of neutropenia

1993 • 116 citations

Role of cell defense against oxidative damage in the resistance of Candida albicans to the killing effect of amphotericin B

1988 • 114 citations

The Lipid Composition of Azole-sensitive and Azole-resistant Strains of Candida albicans

1986 • 100 citations

Azole resistance inCandida albicans

1984 • 98 citations

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1986 • 97 citations

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1984 • 89 citations

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1986 • 67 citations

The effects of azole and polyene antifungals on the plasma membrane enzymes ofCandida albicans

1987 • 65 citations

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1991 • 62 citations

Chemotherapy of Fungal Diseases

1990 • 50 citations

A comparison of the sterol content of multiple isolates of the Candida albicans Darlington strain with other clinically azole‐sensitive and ‐resistant strains

1990 • 46 citations

Drug resistance in human pathogenic fungi

1992 • 46 citations

Inhibition of 14 α-sterol demethylase activity inCandida albicansDarlington does not correlate with resistance to azole

1987 • 37 citations

Drug Resistance in Candida albicans and Candida glabrataa

1988 • 30 citations

Isolation and Characterization of Fluoropyrimidine‐Resistant Mutants in Two Candida Species

1988 • 23 citations

Mechanism of resistance to terbinafine in two isolates of Ustilago maydis

1990 • 17 citations

Mode of action of terbinafine in Ustilago maydis and characterization of resistant mutants

1990 • 14 citations

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