Prostaglandin H synthase and hydroperoxides: Peroxidase reaction and inactivation kinetics

Mechanism for irreversible self-deactivation of prostaglandin synthetase.

1976 • 600 citations

Prostaglandin hydroperoxidase, an integral part of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes.

1979 • 375 citations

Oxygenation of polyunsaturated fatty acids during prostaglandin biosynthesis by sheep vesicular glands

1972 • 362 citations

THE KINETICS OF THE ENZYME-SUBSTRATE COMPOUND OF PEROXIDASE

1943 • 331 citations

The kinetics and stoichiometry of the transition from the primary to the secondary peroxidase peroxide complexes

1952 • 281 citations

Requirements for hydroperoxide by the cyclooxygenase and peroxidase activities of prostaglandin H synthase

1983 • 277 citations

Co-oxygenation of organic substrates by the prostaglandin synthetase of sheep vesicular gland.

1975 • 209 citations

FACTORS REGULATING THE BIOSYNTHESIS OF VARIOUS PROSTAGLANDINS

1971 • 203 citations

Spectral properties of the higher oxidation states of prostaglandin H synthase.

1985 • 159 citations

Chemical Nature of the Secondary Hydrogen Peroxide Compound Formed by Cytochrome-C Peroxidase and Horseradish Peroxidase

1952 • 153 citations

Oxygen Radicals in Chemistry and Biology

1984 • 121 citations

Studies on Cytochrome c Peroxidase

1966 • 119 citations

The substrate profiles of the acidic and slightly basic horseradish peroxidases

1974 • 87 citations

The cytochrome c peroxidase-catalyzed oxidation of ferrocytochrome c by hydrogen peroxide. Steady state kinetic mechanism.

1982 • 45 citations

Quantitative similarities in the several actions of cyanide on prostaglandin H synthase

1985 • 42 citations

Prostaglandin H synthase: An example of enzymic symbiosis

1985 • 37 citations

Peroxidative oxidation of bilirubin during prostaglandin biosynthesis

1985 • 21 citations