Strong Cytotoxic T Cell and Weak Neutralizing Antibody Responses in a Subset of Persons with Stable Nonprogressing HIV Type 1 Infection

Rapid and simple method for purification of nucleic acids

1990 • 5,273 citations

Quantitation of Human Immunodeficiency Virus Type 1 in the Blood of Infected Persons

1989 • 1,090 citations

Virologic and Immunologic Characterization of Long-Term Survivors of Human Immunodeficiency Virus Type 1 Infection

1995 • 1,044 citations

Absence of Intact nef Sequences in a Long-Term Survivor with Nonprogressive HIV-1 Infection

1995 • 1,008 citations

Studies in Subjects with Long-Term Nonprogressive Human Immunodeficiency Virus Infection

1995 • 750 citations

Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics.

1995 • 650 citations

Rapid and simple PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasma: application to acute retroviral infection

1994 • 576 citations

High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors

1995 • 519 citations

Long-term HIV-1 infection without immunologic progression

1994 • 382 citations

Antigenic oscillations and shifting immunodominance in HIV-1 infections

1995 • 325 citations

Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression

1995 • 289 citations

Long-term culture and fine specificity of human cytotoxic T-lymphocyte clones reactive with human immunodeficiency virus type 1.

1989 • 241 citations

A Model-Based Estimate of the Mean Incubation Period for AIDS in Homosexual Men

1988 • 240 citations

Long-term symptomless HIV-1 infection in recipients of blood products from a single donor

1992 • 239 citations

T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS

1994 • 235 citations

Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire.

1994 • 232 citations

HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells and cloned effector cells.

1991 • 191 citations

Application OF Branched DNA Signal Amplification to Monitor Human Immunodeficiency Virus Type 1 Burden in Human Plasma

1994 • 175 citations

Virus Burden in Long-Term Survivors of Human Immunodeficiency Virus (HIV) Infection Is a Determinant of Anti-HIV CD8+ Lymphocyte Activity

1995 • 157 citations

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells.

1993 • 134 citations

Bi-specific monoclonal antibodies: selective binding and complement fixation to cells that express two different surface antigens.

1987 • 114 citations

Limiting dilution analysis of cytotoxic T lymphocytes to human immunodeficiency virus gag antigens in infected persons: in vitro quantitation of effector cell populations with p17 and p24 specificities.

1991 • 111 citations

High frequency of memory and effector gag specific cytotoxic T lymphocytes in HIV seropositive individuals

1990 • 110 citations

Detection of a vigorous HIV-1-specific cytotoxic T lymphocyte response in cerebrospinal fluid from infected persons with AIDS dementia complex.

1992 • 107 citations

Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus

1995 • 91 citations

Absence of Recoverable Infectious Virus and Unique Immune Responses in an Asymptomatic HIV⁺Long-Term Survivor

1994 • 75 citations

Normal Immune Function and Inability to Isolate Virus in Culture in an Individual with Long-Term Human Immunodeficiency Virus Type 1 Infection*

1994 • 65 citations

A Novel Method for Detection andex VivoExpansion of HIV Type 1-Specific Cytolytic T Lymphocytes

1994 • 50 citations

Ex Vivo Expansion of CD4 Lymphocytes from Human Immunodeficiency Virus Type 1-Infected Persons in the Presence of Combination Antiretroviral Agents

1995 • 41 citations