Loss of interleukin 4 receptor-associated molecule gp200-MR6 in human breast cancer: prognostic significance

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

Identification of a T cell-derived b cell growth factor distinct from interleukin 2.

1982 • 1,095 citations

Murine interleukin-4 displays potent anti-tumor activity in vivo

1989 • 790 citations

Treatment of Established Renal Cancer by Tumor Cells Engineered to Secrete Interleukin-4

1991 • 733 citations

IL-4 regulates endothelial cell activation by IL-1, tumor necrosis factor, or IFN-gamma.

1990 • 311 citations

Receptors for B-cell stimulatory factor-1 expressed on cells of haematopoietic lineage

1987 • 280 citations

Inhibition of colon and breast carcinoma cell growth by interleukin-4.

1992 • 169 citations

Loss of transporter in antigen processing 1 transport protein and major histocompatibility complex class I molecules in metastatic versus primary breast cancer.

1995 • 137 citations

Expression of high-affinity IL-4 receptors on human melanoma, ovarian and breast carcinoma cells

1994 • 127 citations

The human thymus microenvironment: heterogeneity detected by monoclonal anti-epithelial cell antibodies.

1985 • 124 citations

Receptors for Interleukin (IL)-4 Do Not Associate with the Common γChain, and IL-4 Induces the Phosphorylation of JAK2 Tyrosine Kinase in Human Colon Carcinoma Cells

1995 • 117 citations

Interleukin-4 is a potent mitogen for capillary endothelium

1991 • 100 citations

Lymphokine regulation of inflammatory processes: Interleukin-4 stimulates fibroblast proliferation

1988 • 98 citations

Quantitative assays of epidermal growth factor receptor in human breast cancer: Cut‐off points of clinical relevance

1988 • 95 citations

A wide range of human cancers express interleukin 4 (IL4) receptors that can be targeted with chimeric toxin composed of IL4 and Pseudomonas exotoxin

1993 • 69 citations

Interleukin 4 alone and with gamma-interferon or alpha-tumor necrosis factor inhibits cell growth and modulates cell surface antigens on human renal cell carcinomas.

1991 • 64 citations

Expression of high-affinity interleukin 4 receptors on murine sarcoma cells and receptor-mediated cytotoxicity of tumor cells to chimeric protein between interleukin 4 and Pseudomonas exotoxin.

1991 • 49 citations

Interleukin 4 receptor expression on human lung tumors and normal lung.

1991 • 38 citations

Interleukin 4 potentiates the antiproliferative effects of tumor necrosis factor on various tumor cell lines.

1991 • 36 citations

Human tumour-associated NK cells secrete increased amounts of interferon-γ and interleukin-4

1991 • 32 citations

Elevated expression of the interleukin 4 receptor in carcinoma: a target for immunotherapy?

1989 • 31 citations

Functional evidence for a monoclonal antibody that binds to the human IL-4 receptor.

1988 • 30 citations

Interleukin-4 receptor and epidermal growth factor receptor expression in colorectal cancer

1992 • 27 citations

A computer model of the interleukin‐4/receptor complex

1993 • 23 citations

Analysis of the fine distribution of thymic epithelial microenvironmental molecules by immuno-electron microscopy.

1989 • 23 citations

Inhibition of alloreactivity by mAb MR6: differential effects on IL-2- and IL-4-producing human T cells

1994 • 21 citations

Tumour-associated upregulation of the IL-4 receptor complex.

1990 • 15 citations

Structure of the IL4 receptor and signal transduction mechanism of IL4

1993 • 13 citations

Bladder carcinomas and normal urothelium universally express gp200-MR6, a molecule functionally associated with the interleukin 4 receptor (CD 124)

1996 • 10 citations

IL-2 inhibits the induction of systemic antitumour immunity by IL-4 in the peritumoural treatment of experimental melanoma.

1993 • 5 citations

[Induction of tumor immunity by cytokine cDNA transfected Lewis lung carcinoma].

1992 • 2 citations