Culture at High Density Increases Phosphoenolpyruvate Carboxykinase Messenger RNA in H4IIEC3 Hepatoma Cells

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

1982 • 1,333 citations

Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver.

1987 • 547 citations

Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes.

1988 • 534 citations

Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type

1983 • 511 citations

Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin.

1984 • 436 citations

A practical approach for quantitating specific mRNAs by solution hybridization

1983 • 427 citations

cAMP stimulates transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase in rat liver nuclei.

1982 • 410 citations

Changes in Liver-Specific Compared to Common Gene Transcription During Primary Culture of Mouse Hepatocytes

1983 • 316 citations

HEPATOMAS IN TISSUE CULTURE COMPARED WITH ADAPTING LIVER IN VIVO.

1964 • 314 citations

The control of mRNA production, translation and turnover in suspended and reattached anchorage-dependent fibroblasts

1978 • 293 citations

Dependence of liver-specific transcription on tissue organization.

1985 • 230 citations

Density-Dependent Growth Control of Adult Rat Hepatocytes in Primary Culture1

1983 • 199 citations

Cell adhesion induces expression of growth-associated genes in suspension-arrested fibroblasts.

1988 • 174 citations

Identification of basal and cyclic AMP regulatory elements in the promoter of the phosphoenolpyruvate carboxykinase gene.

1988 • 169 citations

Cyclic AMP stabilizes the mRNA for phosphoenolpyruvate carboxykinase (GTP) against degradation.

1988 • 165 citations

Posttranscriptional modulation of gene expression in cultured rat hepatocytes.

1984 • 161 citations

Nucleotide sequence of the human γ cytoskeletal actin mRNA: anomalous evolution of vertebrate non-muscle actin genes

1986 • 161 citations

Induction of albumin gene transcription in hepatocytes by extracellular matrix proteins.

1990 • 157 citations

Cell Shape: Determinants, Regulation, and Regulatory Role

1989 • 149 citations

A novel regulatory mechanism for whey acidic protein gene expression.

1989 • 137 citations

Characterization of the cAMP responsive elements from the genes for the alpha-subunit of glycoprotein hormones and phosphoenolpyruvate carboxykinase (GTP). Conserved features of nuclear protein binding between tissues and species.

1988 • 121 citations

Differential patterns of transcript accumulation during human myogenesis.

1987 • 120 citations

Persistence of liver-specific messenger RNA in cultured hepatocytes: different regulatory events for different genes.

1987 • 119 citations

Location and characterization of two widely separated glucocorticoid response elements in the phosphoenolpyruvate carboxykinase gene.

1988 • 113 citations

Transcriptional and post-transcriptional control of specific messenger RNAs in adult and embryonic liver

1984 • 113 citations

Liver-Specific RNA Metabolism in Hepatoma Cells: Variations in Transcription Rates and mRNA Levels

1985 • 91 citations

N6,O2'-dibutyryl cycle AMP and glucose regulate the amount of messenger RNA coding for hepatic phosphoenolpyruvate carboxykinase (GTP).

1982 • 91 citations

Thyroid hormone regulates transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase (GTP) in rat liver

1985 • 88 citations

The effect of phorbol esters and diacylglycerol on expression of the phosphoenolpyruvate carboxykinase (GTP) gene in rat hepatoma H4IIE cells.

1986 • 80 citations

Regulation of growth and differentiation of a rat hepatoma cell line by the synergistic interactions of hormones and collagenous substrata.

1983 • 79 citations

Extracellular matrix components influence DNA synthesis of rat hepatocytes in primary culture

1986 • 75 citations

Effects of Extracellular Matrix on Hepatocyte Growth and Gene Expression: Implications for Hepatic Regeneration and the Repair of Liver Injury

1990 • 74 citations

Construction and cloning of rat albumin structural gene sequences.

1979 • 58 citations

Macrophage-mediated modulation of hepatic function in multiple-system failure

1985 • 46 citations

The structure of tyrosine aminotransferase

1989 • 38 citations

Regulation of Expression of the Messenger Ribonucleic Acid Encoding the Cytosolic Form of Phosphoenolpyruvate Carboxykinase in Liver and Small Intestine of Lactating Rats*

1989 • 26 citations

The 5′ region of the rat phosphoenolpyruvate carboxykinase gene confers pH sensitivity to chimeric genes expressed in renal and liver cell lines capable of expressing pepck

1989 • 18 citations

Insulin Decreases H4IIE Cell PEPCK mRNA by a Mechanism That Does Not Involve cAMP

1986 • 15 citations

Cell Shape and Cell Contacts: Molecular Approaches to Cytoskeleton Expression

1989 • 13 citations