SDHD mutations in head and neck paragangliomas result in destabilization of complex II in the mitochondrial respiratory chain with loss of enzymatic activity and abnormal mitochondrial morphology

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

1998 • 1,864 citations

Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma

2000 • 1,604 citations

Gene Mutations in the Succinate Dehydrogenase Subunit SDHB Cause Susceptibility to Familial Pheochromocytoma and to Familial Paraganglioma

2001 • 1,082 citations

Histochemistry, Theoretical and Applied.

1972 • 960 citations

Mutations in SDHC cause autosomal dominant paraganglioma, type 3

2000 • 877 citations

Gastric Stromal Sarcoma, Pulmonary Chondroma, and Extra-adrenal Paraganglioma (Carney Triad): Natural History, Adrenocortical Component, and Possible Familial Occurrence

1999 • 435 citations

Cellular oxygen sensing by mitochondria: old questions, new insight

2000 • 392 citations

A role for mitochondrial enzymes in inherited neoplasia and beyond

2003 • 387 citations

The R22X Mutation of the SDHD Gene in Hereditary Paraganglioma Abolishes the Enzymatic Activity of Complex II in the Mitochondrial Respiratory Chain and Activates the Hypoxia Pathway

2001 • 356 citations

Oxygen sensing by the carotid body chemoreceptors

2000 • 276 citations

Hereditary paraganglioma targets diverse paraganglia

2002 • 226 citations

Functional Consequences of aSDHBGene Mutation in an Apparently Sporadic Pheochromocytoma

2002 • 210 citations

Nearly all hereditary paragangliomas in The Netherlands are caused by two founder mutations in the SDHD gene

2001 • 166 citations

Up-Regulation of PTHrP and Bcl-2 Expression Characterizes the Progression of Osteochondroma towards Peripheral Chondrosarcoma and Is a Late Event in Central Chondrosarcoma

2000 • 143 citations

Progress in understanding structure–function relationships in respiratory chain complex II

2000 • 131 citations

Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas

2003 • 111 citations

Molecular Genetics of Succinate:Quinone Oxidoreductase in Eukaryotes

1998 • 110 citations

Analysis of a second family with hereditary non-chromaffin paragangliomas locates the underlying gene at the proximal region of chromosome 11q

1993 • 92 citations

Cytopathies involving mitochondrial complex II

2002 • 81 citations

The Structural Analysis of Adhesions Mediated by Ep-CAM

1999 • 80 citations

Anti-biotin Antibodies Offer Superior Organelle-specific Labeling of Mitochondria over Avidin or Streptavidin

1997 • 80 citations

Phenotypic dichotomy in mitochondrial complex II genetic disorders

2001 • 76 citations

Deficiency of complex II of the mitochondrial respiratory chain in late‐onset optic atrophy and ataxia

1996 • 74 citations

Assessment of Problems in Diagnostic and Research Immunohistochemistry Associated With Epitope Instability in Stored Paraffin Sections

2000 • 66 citations

Isolation and characterization of the Saccharomyces cerevisiae SDH4 gene encoding a membrane anchor subunit of succinate dehydrogenase.

1994 • 64 citations

Expression of Angiogenic Growth Factors in Paragangliomas

2000 • 63 citations

Malignant carotid body paraganglioma: Light and electron microscopic study of the tumor and its metastases

1980 • 47 citations

Paragangliomas of the head and neck region show complete loss of heterozygosity at 11 q22-q23 in chief cells and the flow-sorted dna aneuploid fraction

1998 • 43 citations

A Chinese Hamster Mutant Cell Line with a Defect in the Integral Membrane Protein CII-3 of Complex II of the Mitochondrial Electron Transport Chain

1995 • 40 citations

Tissue culture, electron microscopic and enzyme histochemical investigations of extraadrenal paragangliomas.

1976 • 27 citations