Protection against blood–brain barrier disruption in focal cerebral ischemia by the type IV phosphodiesterase inhibitor BBB022: a quantitative study

Reversible middle cerebral artery occlusion without craniectomy in rats.

1989 • 6,875 citations

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

1986 • 2,584 citations

FINE STRUCTURAL LOCALIZATION OF A BLOOD-BRAIN BARRIER TO EXOGENOUS PEROXIDASE

1967 • 2,534 citations

Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors

1990 • 860 citations

Middle Cerebral Artery Occlusion in the Rat by Intraluminal Suture

1996 • 772 citations

A cell culture model of the blood-brain barrier.

1991 • 753 citations

Occludin as a possible determinant of tight junction permeability in endothelial cells

1997 • 626 citations

Development of the blood-brain barrier

1990 • 533 citations

Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats

1996 • 500 citations

Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes

1991 • 468 citations

THE BINDING OF T-1824 AND STRUCTURALLY RELATED DIAZO DYES BY THE PLASMA PROTEINS

1943 • 353 citations

Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats.

1989 • 349 citations

Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in rats.

1994 • 329 citations

Evidence that tyrosine phosphorylation may increase tight junction permeability

1995 • 318 citations

Ischemic brain edema following occlusion of the middle cerebral artery in the rat. I: The time courses of the brain water, sodium and potassium contents and blood-brain barrier permeability to 125I-albumin.

1985 • 300 citations

Quantitative Evaluation of Vascular Permeability in the Gerbil Brain after Transient Ischemia Using Evans Blue Fluorescence

1988 • 271 citations

Role of cyclic adenosine monophosphate in the induction of endothelial barrier properties

1989 • 251 citations

Selective Vulnerability of the Blood-Brain Barrier in Chemically Induced Lesions^*

1966 • 223 citations

Evaluation of the dye-protein tracers in pathophysiology of the blood-brain barrier

1981 • 219 citations

Hypoxia-induced increased permeability of endothelial monolayers occurs through lowering of cellular cAMP levels

1992 • 197 citations

The blood-brain barrier. Transport across the cerebral endothelium.

1985 • 184 citations

Increased permeability of cerebral vessels to horseradish peroxidase induced by ischemia in Mongolian Gerbils.

1976 • 135 citations

Isolated microvessels: the blood-brain barrier in vitro.

1978 • 126 citations

Nitric oxide and endothelin secretion by brain microvessel endothelial cells: Regulation by cyclic nucleotides

1993 • 123 citations

Cell adhesion, cell junctions and the blood—brain barrier

1996 • 110 citations

HU-211, a Novel Noncompetitive N -Methyl- <scp>d-</scp> Aspartate Antagonist, Improves Neurological Deficit and Reduces Infarct Volume After Reversible Focal Cerebral Ischemia in the Rat

1995 • 97 citations

Could isoenzyme-selective phosphodiesterase inhibitors render bronchodilator therapy redundant in the treatment of bronchial asthma?

1992 • 97 citations

Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor

1994 • 70 citations

Prostaglandin synthesis and oedema formation during reperfusion following experimental brain ischaemia in the gerbil.

1984 • 69 citations

Recovery of sensorimotor function after distal middle cerebral artery photothrombotic occlusion in rats.

1994 • 67 citations

The Physiology of the Blood-Brain Barrier

1990 • 66 citations

Rolipram, a cyclic AMP-selective phosphodiesterase inhibitor, reduces neuronal damage following cerebral ischemia in the gerbil

1995 • 61 citations

Effects of dexamethasone on brain edema induced by kainic acid seizures

1986 • 48 citations

Morphofunctional Aspects of the Normal and Pathological Blood-Brain Barrier

1983 • 41 citations

Disruption of blood-brain barrier following bilateral carotid artery occlusion in spontaneously hypertensive rats. A quantitative study.

1983 • 23 citations

The influence of the calcium antagonist nimodipine and induced hypertension on the behavior of the cerebral pial arteries, the blood-brain barrier, cerebral edema, and cerebral infarction in cats with one-hour occlusion of the middle cerebral artery

1991 • 22 citations

The Influence of the Calcium Antagonist Nimodipine and Induced Hypertension on the Behavior of the Cerebral Pial Arteries, the Blood-Brain Barrier, Cerebral Edema, and Cerebral Infarction in Cats with One-Hour Occlusion of the Middle Cerebral Artery

1991 • 15 citations