Bone Morphogenetic Protein 4 Mediates Apoptosis of Capillary Endothelial Cells during Rat Pupillary Membrane Regression

Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis

1997 • 3,470 citations

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1993 • 3,111 citations

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

1996 • 1,959 citations

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

1997 • 1,774 citations

The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling

1997 • 1,328 citations

Smad6 inhibits signalling by the TGF-β superfamily

1997 • 1,026 citations

BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning.

1995 • 1,021 citations

Anchorage dependence, integrins, and apoptosis

1994 • 1,016 citations

Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

1993 • 908 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development

1997 • 705 citations

Bone Morphogenetic Proteins Promote Astroglial Lineage Commitment by Mammalian Subventricular Zone Progenitor Cells

1996 • 681 citations

Bone morphogenetic proteins in development

2004 • 678 citations

A human Mad protein acting as a BMP-regulated transcriptional activator

1996 • 674 citations

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase.

1997 • 569 citations

Requirement for BMP Signaling in Interdigital Apoptosis and Scale Formation

1996 • 552 citations

Hemodynamic forces are complex regulators of endothelial gene expression

1995 • 547 citations

The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest

1994 • 486 citations

Smads and early developmental signaling by the TGFβ superfamily

1998 • 485 citations

bcl-xLx is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria

1994 • 435 citations

BMP4 is essential for lens induction in the mouse embryo

1998 • 435 citations

Bone morphogenetic proteins in the nervous system

1997 • 409 citations

Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development

1997 • 339 citations

BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo

1999 • 330 citations

Activin signalling and response to a morphogen gradient

1994 • 328 citations

Role of TGFβs and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod

1996 • 324 citations

Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis.

1998 • 311 citations

BMP7 Null Mutation in Mice: Developmental Defects in Skeleton, Kidney, and Eye

1997 • 230 citations

Differential Inhibition of Smad6 and Smad7 on Bone Morphogenetic Protein- and Activin-mediated Growth Arrest and Apoptosis in B Cells

1999 • 225 citations

Apoptosis (Programmed Cell Death) in Arteries of the Neonatal Lamb

1995 • 200 citations

Problems and paradigms: Morphogens and pattern formation

1997 • 184 citations

Apoptosis during macrophage-dependent ocular tissue remodelling

1994 • 166 citations

Lack of Hemodynamic Forces Triggers Apoptosis in Vascular Endothelial Cells

1997 • 163 citations

BMP4 Mediates Apoptotic Cell Death in the Developing Chick Eye

2001 • 157 citations

Macrophages induce apoptosis in normal cells in vivo

1997 • 154 citations

Msx2 Is a Transcriptional Regulator in the BMP4-Mediated Programmed Cell Death Pathway

1997 • 153 citations

VEGF deprivation-induced apoptosis is a component of programmed capillary regression

1999 • 144 citations

Mechanism of deletion of endothelial cells during regression of the corpus luteum.

1984 • 143 citations

Smad7 Is an Activin-inducible Inhibitor of Activin-induced Growth Arrest and Apoptosis in Mouse B Cells

1998 • 139 citations

Ectopic Expression ofMsx-2in Posterior Limb Bud Mesoderm Impairs Limb Morphogenesis While InducingBMP-4Expression, Inhibiting Cell Proliferation, and Promoting Apoptosis

1998 • 105 citations

Endothelial cell apoptosis in capillary network remodeling

1999 • 103 citations

The ductus arteriosus

1973 • 96 citations

Apoptosis Occurs in Endothelial Cells during Hypertension-Induced Microvascular Rarefaction

1997 • 90 citations

Ductus arteriosus. Advanced differentiation of smooth muscle cells demonstrated by myosin heavy chain isoform expression in rabbits.

1993 • 84 citations

BMPs, Smads and metalloproteases: extracellular and intracellular modes of negative regulation

1998 • 75 citations

Detection of Multiple Bone Morphogenetic Protein Messenger Ribonucleic Acids and Their Signal Transducer, Smad1, During Mouse Decidualization1

2000 • 70 citations

Nerve Growth Factor Determines Survival and Death of PC12 Cells by Regulation of the bcl‐x, bax, and caspase‐3 Genes

1999 • 68 citations

Expression of Smad1 and Smad2 during embryogenesis suggests a role in organ development

1998 • 58 citations

BMP 7 Is Required for Nephrogenesis, Eye Development, and Skeletal Patterninga

1996 • 55 citations