Biological consequences of overexpressing or eliminating N-acetylglucosaminyltransferase-TIII in the mouse

β1-6 Branching of Asn-Linked Oligosaccharides Is Directly Associated with Metastasis

1987 • 929 citations

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

1999 • 751 citations

Characterization of the structural determinants required for the high affinity interaction of asparagine-linked oligosaccharides with immobilized Phaseolus vulgaris leukoagglutinating and erythroagglutinating lectins.

1982 • 536 citations

Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection.

1995 • 276 citations

Control of glycoprotein synthesis. UDP-GlcNAc:glycopeptide beta 4-N-acetylglucosaminyltransferase III, an enzyme in hen oviduct which adds GlcNAc in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-glycosyl oligosaccharides.

1982 • 225 citations

Aberrant Glycosylation of E-cadherin Enhances Cell-Cell Binding to Suppress Metastasis

1996 • 203 citations

Genetic remodeling of protein glycosylation in vivo induces autoimmune disease

2001 • 186 citations

N-acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis.

1993 • 116 citations

cDNA Cloning, Expression, and Chromosomal Localization of Human N-Acetylglucosaminyltransferase III (GnT-III)1

1993 • 111 citations

Isolation, characterization and inactivation of the mouse Mgat3 gene: the bisecting N-acetylglucosamine in asparagine-linked oligosaccharides appears dispensable for viability and reproduction

1997 • 102 citations

A dominant mutation to ricin resistance in Chinese hamster ovary cells induces UDP-GlcNAc:glycopeptide beta-4-N-acetylglucosaminyltransferase III activity.

1984 • 100 citations

Expression of N-acetylglucosaminyltransferase III in hepatic nodules during rat liver carcinogenesis promoted by orotic acid.

1988 • 95 citations

The Addition of Bisecting N-Acetylglucosamine Residues to E-cadherin Down-regulates the Tyrosine Phosphorylation of β-Catenin

2001 • 94 citations

The biosynthesis of highly branched N-glycans: studies on the sequential pathway and functional role of N-actylglucosaminyltransferases I, II, III, IV, V and VI

1988 • 94 citations

Bisecting N-acetylglucosamine on K562 cells suppresses natural killer cytotoxicity and promotes spleen colonization.

1996 • 93 citations

Overexpression of N-Acetylglucosaminyltransferase III Enhances the Epidermal Growth Factor-induced Phosphorylation of ERK in HeLaS3 Cells by Up-regulation of the Internalization Rate of the Receptors

2001 • 91 citations

Gene Transfection-mediated Overexpression of β1,4-N-Acetylglucosamine Bisecting Oligosaccharides in Glioma Cell Line U373 MG Inhibits Epidermal Growth Factor Receptor Function

1997 • 81 citations

Overexpression of N-Acetylglucosaminyltransferase III Disrupts the Tyrosine Phosphorylation of Trk with Resultant Signaling Dysfunction in PC12 Cells Treated with Nerve Growth Factor

1997 • 74 citations

N-Glycosylation is requisite for the enzyme activity and Golgi retention of N-acetylglucosaminyltransferase III

1997 • 66 citations

Characterization of cis-Acting Elements of the Gene for Macrophage-stimulating Protein from the Human

1996 • 63 citations

N-Acetylglucosaminyltransferase III in human serum, and liver and hepatoma tissues: Increased activity in liver cirrhosis and hepatoma patients

1989 • 56 citations

Ectopic expression of N -acetylglucosaminyltransferase III in transgenic hepatocytes disrupts apolipoprotein B secretion and induces aberrant cellular morphology with lipid storage

1998 • 54 citations

High expression of an N-acetylglucosaminyltransferase III in 3′-methyl DAB-induced hepatoma and ascites hepatoma

1988 • 51 citations

Tetracycline-Regulated overexpression of glycosyltransferases in Chinese hamster ovary cells

1999 • 48 citations

The relation of three-dimensional structure to biosynthesis in the N-linked oligosaccharides

1983 • 48 citations

Progression of hepatic neoplasms is severely retarded in mice lacking the bisecting N-acetylglucosamine on N-glycans: evidence for a glycoprotein factor that facilitates hepatic tumor progression.

1998 • 46 citations

Cloning and chromosomal mapping of the mouse Mgat3 gene encoding N-acetylglucosaminyltransferase III

1995 • 45 citations

Strain differences in hepatic tumor promotion by phenobarbital in diethylnitrosamine- and dimethylnitrosamine-initiated infant male mice

1989 • 35 citations

High expression of udp‐n‐acetylglucosamine: β‐d mannoside β‐1, 4‐n‐acetylglucosaminyltransferase III (GnT‐III) in chronic myelogenous leukemia in blast crisis

1995 • 35 citations

Synthesis of Bisected Glycoforms of Recombinant IFN‐β by Overexpression of β‐1,4‐N‐Acetylglucosaminyltransferase III in Chinese Hamster Ovary Cells

1998 • 34 citations

New evidence for an extra-hepatic role of N-acetylglucosaminyltransferase III in the progression of diethylnitrosamine-induced liver tumors in mice.

2000 • 32 citations

Remodeling of glycoconjugates on CD44 enhances cell adhesion to hyaluronate, tumor growth and metastasis in B16 melanoma cells expressing β1,4-N-acetylglucosaminyltransferase III

1997 • 32 citations

β-1,4-mannosyl-glycoprotein β-1,4-N-acetylglucosaminyltransferase III activity in human B and T lymphocyte lines and in tonsillar B and T lymphocytes

1988 • 25 citations

Lectin Receptors and Lectin Resistance in Chinese Hamster Ovary Cells

1977 • 24 citations

Human N‐Acetylglucosaminyltransferase III Gene is Transcribed from Multiple Promoters

1996 • 23 citations

Expression of N-acetylglucosaminyltransferase III in hepatic nodules generated by different models of rat liver carcinogenesis

1989 • 21 citations

Novel genetic instability associated with a developmental regulated glycosyltransferase locus in Chinese hamster ovary cells

1989 • 19 citations

Bisecting GlcNAc structure is implicated in suppression of stroma-dependent haemopoiesis in transgenic mice expressing N-acetylglucosaminyltransferase III

1998 • 15 citations

Cell Cycle-Dependent Regulation of N-Acetylglucosaminyltransferase-III in a Human Colon Cancer Cell Line, Colo201

2000 • 5 citations