ATP sensitive potassium channels: Potential drug targets in neuropsychopharmacology

Ionic channels of excitable membranes

1985 • 7,199 citations

Ionic Channels of Excitable Membranes

1985 • 3,014 citations

Diversity and ubiquity of K channels

1988 • 1,342 citations

Cloning of a Membrane Protein That Induces a Slow Voltage-Gated Potassium Current

1988 • 511 citations

Antidiabetic sulfonylureas: localization of binding sites in the brain and effects on the hyperpolarization induced by anoxia in hippocampal slices

1989 • 237 citations

Potassium channel modulators: scientific applications and therapeutic promise

1990 • 212 citations

Control of insulin secretion by sulfonylureas, meglitinide and diazoxide in relation to their binding to the sulfonylurea receptor in pancreatic islets

1989 • 174 citations

Alternative splicing contributes to K+ channel diversity in the mammalian central nervous system.

1991 • 172 citations

Site-specific mutations in a minimal voltage-dependent K+ channel alter ion selectivity and open-channel block

1991 • 132 citations

K+ channel openers activate brain sulfonylurea-sensitive K+ channels and block neurosecretion.

1990 • 131 citations

Peptide Toxins and Potassium Channels

1990 • 126 citations

Recent progress in potassium channel opener pharmacology

1992 • 113 citations

A potassium channel activator modulates both excitatory noncholinergic and cholinergic neurotransmission in guinea pig airways.

1990 • 87 citations

Characterization of high affinity binding sites for charybdotoxin in synaptic plasma membranes from rat brain. Evidence for a direct association with an inactivating, voltage-dependent, potassium channel.

1990 • 87 citations

Peptide toxins and potassium channels

1990 • 78 citations

Activation by cromakalim of pre- and post-synaptic ATP-sensitive K+ channels in substantia nigra

1991 • 73 citations

K+ channel openers decrease seizures in genetically epileptic rats

1989 • 72 citations

Actions of BRL 34915 (Cromakalim) upon convulsive discharges in guinea pig hippocampal slices

1988 • 71 citations

Glucose-regulated potassium channels are sweet news for neurobiologists

1990 • 58 citations

Scyllatoxin, a blocker of calcium-activated potassium channels: structure-function relationships and brain localization of the binding sites

1992 • 58 citations

Potassium currents in rat cortical neurons in culture are enhanced by the antiepileptic drug carbamazepine

1990 • 57 citations

ATP-sensitive potassium channels counteract anoxia in neurones of the substantia nigra

1991 • 50 citations

Distribution in the rat central nervous system of acceptor sub-types for dendrotoxin, a K+ channel probe

1989 • 49 citations

Comparison of the distribution of binding sites for the potassium channel ligands [125I]Apamin, [125I]Charybdotoxin and [125I]Iodoglyburide in the rat brain

1993 • 48 citations

Subtypes of K+ channels differentiated by the effect of K+ channel openers upon K+ channel blocker-induced seizures

1989 • 44 citations

Pinacidil potentiates morphine analgesia

1992 • 38 citations

Distribution of acceptors for ß-bungarotoxin in the central nervous system of the rat

1988 • 37 citations

High affinity receptors for the bee venom MCD peptide. Quantitative autoradiographic localization at different stages of brain development and relationship with MCD neurotoxicity

1988 • 32 citations

Quantitative autoradiography of the binding sites for [125I] iodoglyburide, a novel high-affinity ligand for ATP-sensitive potassium channels in rat brain.

1991 • 27 citations

An endogenous ligand for the central sulfonylurea receptor

1988 • 25 citations

A Group of Potassium-Channel Blockers-Acetylcholine Releasers

1992 • 24 citations

Potassium Channel Blockers: Could They Work in Alzheimer Disease?

1991 • 15 citations

Latest developments in K-channel modulator pharmacology.

1991 • 11 citations

Effects of Potassium Channel Openers on Pentylenetetrazole‐Induced Seizures in Mice

1990 • 10 citations

Quantitative autoradiography of [125I] apamin binding sites in the central nervous system.

1984 • 7 citations

Autoradiographic localization of [125I]charybdotoxin binding sites in rat brain

1992 • 5 citations