Ciliary neurotrophic factor is an axogenesis factor for retinal ganglion cells

Requirement for Phosphatidylinositol-3 Kinase in the Prevention of Apoptosis by Nerve Growth Factor

1995 • 1,400 citations

GAP-43: an intrinsic determinant of neuronal development and plasticity

1997 • 1,285 citations

GDNF: a Potent Survival Factor for Motoneurons Present in Peripheral Nerve and Muscle

1994 • 1,261 citations

Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth

1994 • 1,123 citations

Axonal Growth-Associated Proteins

1989 • 1,118 citations

A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration

1994 • 1,068 citations

Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection.

1987 • 1,012 citations

Intracellular Signaling Pathways Activated by Neuropathic Factors

1996 • 958 citations

The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor

1992 • 897 citations

Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading.

1988 • 876 citations

Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture

1995 • 847 citations

Effects of ocular injury and administration ofbrain-derived neurotrophic factor on survival and regrowth of axotomized retinalganglion cells.

1994 • 727 citations

CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130

1992 • 693 citations

Cytokine Receptors and Signal Transduction

1992 • 607 citations

Disruption of the CNTF gene results in motor neuron degeneration

1993 • 566 citations

Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo

1993 • 543 citations

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells

1986 • 519 citations

Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning

1988 • 510 citations

Neuropoietic cytokines in the hematopoietic fold

1991 • 474 citations

Lengthy regrowth of cut axons from ganglion cells after peripheral nerve transplantation into the retina of adult rats

1985 • 390 citations

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

1995 • 376 citations

Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration.

1992 • 365 citations

Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat

1992 • 355 citations

Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain.

1991 • 346 citations

Injury-induced upregulation of bFGF and CNTF mRNAS in the rat retina

1995 • 319 citations

Expression of the growth-associated protein GAP-43 in adult rat retinal ganglion cells following axon injury

1991 • 314 citations

Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo

1992 • 309 citations

The Neurotrophins and CNTF: Two Families of Collaborative Neurotrophic Factors

1996 • 282 citations

Peripheral nerve explants grafted into the vitreous body of the eye promote the regeneration of retinal ganglion cell axons severed in the optic nerve

1996 • 263 citations

Cytokine Receptors and Signal Transduction

1997 • 259 citations

Effect of NGF on the survival of rat retinal ganglion cells following optic nerve section

1989 • 253 citations

Injury‐induced Regulation of Ciliary Neurotrophic Factor mRNA in the Adult Rat Brain

1993 • 251 citations

Retrograde axonal transport of ciliary neurotrophic factor is increased by peripheral nerve injury

1993 • 230 citations

Survival and Axonal Elongation of Adult Rat Retinal Ganglion Cells

1989 • 210 citations

Brain-Derived Neurotrophic Factor and Neurotrophin-4/5 Stimulate Growth of Axonal Branches from Regenerating Retinal Ganglion Cells

1996 • 206 citations

Degenerative and regenerative responses of injured neurons in the central nervous system of adult mammals

1991 • 200 citations

Mitogen-activated Protein Kinase-independent Pathways Mediate the Effects of Nerve Growth Factor and cAMP on Neuronal Survival

1996 • 176 citations

Gap‐43 immunoreactivity and axon regeneration in retinal ganglion cells of the rat

1994 • 171 citations

Neurotrophin‐4/5 (NT‐4/5) increases adult rat retinal ganglion cell survival and neurite outgrowth in vitro

1994 • 169 citations

Acidic and basic fibroblast growth factors in the nervous system: distribution and differential alteration of levels after injury of central versus peripheral nerve

1991 • 161 citations

The survival of chick retinal ganglion cells in response to brain-derived neurotrophic factor depends on their embryonic age

1989 • 154 citations

Different forms of the neurotrophin receptor TrkB mRNA predominate in rat retina and optic nerve

1993 • 151 citations

Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis

1995 • 147 citations

Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system.

1996 • 140 citations

Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system

1996 • 133 citations

Bcl-2 affects survival but not neuronal differentiation of PC12 cells

1993 • 129 citations

Evidence for Multiple, Local Functions of Ciliary Neurotrophic Factor (CNTF) in Retinal Development: Expression of CNTF and Its Receptor and In Vitro Effects on Target Cells

1997 • 125 citations

Effects of GGF/neuregulins on neuronal survival and neurite outgrowth correlate with erbB2/neu expression in developing rat retina

1996 • 119 citations

Expression of NGF receptor and NGF receptor mRNA in the developing and adult rat retina

1991 • 109 citations

Differential inhibition of nerve growth factor responses by purine analogues: correlation with inhibition of a nerve growth factor-activated protein kinase.

1989 • 101 citations

Induction of Neurite Outgrowth by Interleukin-6 Is Accompanied by Activation of Stat3 Signaling Pathway in a Variant PC12 Cell (E2) Line

1996 • 100 citations

Axon Outgrowth Is Regulated by an Intracellular Purine-sensitive Mechanism in Retinal Ganglion Cells

1998 • 99 citations

Cross-linking identifies leukemia inhibitory factor-binding protein as a ciliary neurotrophic factor receptor component.

1993 • 95 citations

Localization of cholinergic differentiation factor/leukemia inhibitory factor mRNA in the rat brain and peripheral tissues.

1991 • 83 citations

Schwann Cells Secrete a PDGF‐like Factor: Evidence for an Autocrine Growth Mechanism involving PDGF

1990 • 77 citations

Retinal ganglion cell survival is promoted by genetically modified astrocytes designed to secrete brain-derived neurotrophic factor (BDNF)

1994 • 72 citations

Role of neurotrophins in the control of neural development: Neurotrophin-3 promotes both neuron differentiation and survival of cultured chick retinal cells

1994 • 72 citations

Changes in rapidly transported proteins in developing hamster retinofugal axons

1988 • 71 citations

Characterization of interleukin-11 receptor and protein tyrosine phosphorylation induced by interleukin-11 in mouse 3T3-L1 cells.

1992 • 69 citations

Nerve growth factor reduces apoptosis of axotomized retinal ganglion cells in the neonatal rat

1994 • 66 citations

Two factors secreted by the goldfish optic nerve induce retinal ganglion cells to regenerate axons in culture

1995 • 59 citations

Purine analogs inhibit nerve growth factor-promoted neurite outgrowth by sympathetic and sensory neurons

1990 • 58 citations

Injury induced expression of growth-associated protein-43 in adult mouse retinal ganglion cells In vitro

1994 • 55 citations

Characterization of the sprouting response of axon-like processes from retinal ganglion cells after axotomy in adult hamsters: a model using intravitreal implantation of a peripheral nerve

1992 • 50 citations

Influence of peripheral nerve grafts on the expression of GAP-43 in regenerating retinal ganglion cells in adult hamsters

1995 • 46 citations

Rat ciliary neurotrophic factor (CNTF): Gene structure and regulation of mRNA levels in glial cell cultures

1993 • 43 citations

Expression of ciliary neurotrophic factor receptor mRNA and protein in the early postnatal and adult rat nervous system

1994 • 41 citations

Ciliary neurotrophic factor stimulates neurite outgrowth from spinal cord neurons

1996 • 41 citations

Developmental expression of trkB and low-affinity NGF receptor in the rat retina

1993 • 39 citations

Developing Rat Retinal Ganglion Cells Express the Functional NGF Receptor p140trkA

1993 • 37 citations

Intravitreal Transplantation of a Segment of Peripheral Nerve Enhances Axonal Regeneration of Retinal Ganglion Cells Following Distal Axotomy

1994 • 29 citations

Expression and characterization of recombinant human ciliary neurotrophic factor from Escherichia coli

1991 • 27 citations

Choroid coat extract and ciliary neurotrophic factor strongly promote neurite outgrowth in the embryonic chick retina

1994 • 13 citations

Regeneration and plasticity in the mammalian visual system

1992 • 11 citations