Insulin-Like Growth Factors are Mitogenic for Human Keratinocytes and a Squamous Cell Carcinoma

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*

1989 • 1,796 citations

Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes

1977 • 1,063 citations

Insulin-like growth factor II receptor as a multifunctional binding protein

1987 • 858 citations

The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor.

1982 • 709 citations

An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I.

1987 • 682 citations

Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium.

1986 • 559 citations

Growth hormone-dependent insulin-like growth factor (IGF) binding protein both inhibits and potentiates IGF-I-stimulated DNA synthesis in human skin fibroblasts

1988 • 488 citations

Role of platelet-derived growth factor in wound healing: synergistic effects with other growth factors.

1987 • 421 citations

Cloning and Expression of the Growth Hormone-Dependent Insulin-Like Growth Factor-Binding Protein

1988 • 367 citations

Isolation of an inhibitory insulin-like growth factor (IGF) binding protein from bone cell-conditioned medium: a potential local regulator of IGF action.

1989 • 358 citations

Insulin-Like Growth Factor (IGF) Binding Protein from Human Decidua Inhibits the Binding and Biological Action of IGF-I in Cultured Choriocarcinoma Cells**

1988 • 347 citations

Expression and characterization of a functional human insulin-like growth factor I receptor.

1988 • 313 citations

Insulinlike Growth Factor-Binding Proteins

1990 • 291 citations

Demonstration of Specific Plasma Protein Binding Sites For Somatomedin

1977 • 272 citations

Binding of nonsuppressible insulinlike activity to human serum

1975 • 253 citations

Cloning, characterization, and expression of a human insulin-like growth factor binding protein

1988 • 249 citations

Soluble 34K Binding Protein Inhibits the Binding of Insulin-like Growth Factor I to Its Cell Receptors in Human Secretory Phase Endometrium: Evidence for Autocrine/Paracrine Regulation of Growth Factor Action*

1988 • 249 citations

Cloning, sequence analysis and expression of a cDNA encoding a novel insulin-like growth factor binding protein (IGFBP-2).

1989 • 240 citations

Purification of a 31,000-dalton insulin-like growth factor binding protein from human amniotic fluid. Isolation of two forms with different biologic actions.

1988 • 233 citations

Insulin-Like Growth Factor (IGF) Binding Protein Complementary Deoxyribonucleic Acid from Human HEP G2 Hepatoma Cells: Predicted Protein Sequence Suggests an IGF Binding Domain Different from Those of the IGF-I and IGF-II Receptors

1988 • 232 citations

Cultured fibroblast monolayers secrete a protein that alters the cellular binding of somatomedin-C/insulinlike growth factor I.

1986 • 231 citations

Structure of the Receptor for Insulin-Like Growth Factor II: The Puzzle Amplified

1988 • 206 citations

Heterogeneity of insulin‐like growth factor binding proteins and relationships between structure and affinity

1987 • 173 citations

Stimulation of Growth of Keratinocytes by Basic Fibroblast Growth Factor

1988 • 172 citations

Modulation of insulinlike growth factor I binding to human fibroblast monolayer cultures by insulinlike growth factor carrier proteins released to the incubation media.

1986 • 130 citations

Control of growth and differentiation in vitro of human keratinocytes cultured in serum-free medium

1987 • 119 citations

Identification of an insulin‐like growth factor‐binding protein in human cerebrospinal fluid with a selective affinity for IGF‐II

1986 • 118 citations

Insulin-like growth factor binding proteins from cultured human fibroblasts. Characterization and hormonal regulation.

1989 • 116 citations

Isolation from human cerebrospinal fluid of a new insulin‐like growth factor‐binding protein with a selective affinity for IGF‐II

1989 • 116 citations

The somatomedin-binding protein isolated from a human hepatoma cell line is identical to the human amniotic fluid somatomedin-binding protein

1985 • 99 citations

Effect of an anti-insulin-like growth factor I receptor antibody on insulin-like growth factor II stimulation of DNA synthesis in human fibroblasts

1986 • 98 citations

Basic fibroblast growth factor and insulin‐like growth factor I are strong mitogens for cultured mouse keratinocytes

1988 • 92 citations

Insulin-Like Growth Factor-Binding Proteins (IGF-BPs) Produced by Human Skin Fibroblasts: Immunological Relationship to Other Human IGF-BPs*

1988 • 78 citations

Stimulation of Thymidine Incorporation in Keratinocytes by Insulin, Epidermal Growth Factor, and Placental Extract: Comparison With Cell Number to Assess Growth

1988 • 73 citations

Characterization of Insulin-Like Growth Factor Binding Proteins from Human Breast Cancer Cells

1989 • 70 citations

Comparative effects of somatomedin C and insulin on the metabolism and growth of cultured human fibroblasts

1985 • 66 citations

Receptors for Insulin-Like Growth Factors and Growth Effects of Multiplication-Stimulating Activity (Rat Insulin-Like Growth Factor II) in Rat Embryo Fibroblasts*

1983 • 64 citations

Structural and Immunological Comparison of Insulin-Like Growth Factor Binding Proteins of Cerebrospinal and Amniotic Fluids*

1989 • 63 citations

The insulin-like growth factor-binding protein superfamily

2000 • 56 citations

Characterization of Insulin-Like Growth Factor-I/Somatomedin-C Receptors on Human Keratinocyte Monolayers

1986 • 51 citations

Insulin Binding Properties of Normal and Transformed Human Epidermal Cultured Keratinocytes

1985 • 47 citations

Keratinocyte proliferation in wound healing and skin diseases

1988 • 46 citations

Selective Enrichment of Human Epidermal Cell Subpopulations Using Monoclonal Antibodies

1983 • 45 citations

Spontaneous establishment and characterization of mouse keratinocyte cell lines in serum-free medium

1988 • 35 citations

Somatomedin Receptors: Structure, Function, and Regulation

1986 • 27 citations

Further Characterization of the Keratinocyte Somatomedin-C/Insulin-like Growth Factor I (SM-C/IGF-I) Receptor and the Biological Responsiveness of Cultured Keratinocytes to SM-C/IGF-I

1988 • 23 citations

Transiently Increased Insulin-Like Growth Factor. I. Immunoreactivity in UVB-irradiated Mouse Skin

1988 • 20 citations